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sdhA sdhA hemN hemN dusA dusA frdD frdD frdC frdC frdB frdB frdA frdA EHY67350.1 EHY67350.1 wecC wecC fabV fabV cobA cobA dusB dusB EHY68819.1 EHY68819.1 EHY68667.1 EHY68667.1 tyrA tyrA hemF hemF EHY71203.1 EHY71203.1 EHY71202.1 EHY71202.1 dusC dusC fabI fabI EHY70459.1 EHY70459.1 caiA_1 caiA_1 hpaB hpaB pyrD pyrD EHY69756.1 EHY69756.1 sdhB sdhB hemG hemG sdhD sdhD sdhC sdhC dhbA dhbA fadE fadE caiA caiA dapB dapB
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
sdhAKEGG: spt:SPA2009 0. sdhA; succinate dehydrogenase flavoprotein subunit K00239; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM0734; sdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
hemNKEGG: stm:STM4004 6.6e-242 hemN; coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4004; hemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa)
dusAtRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (339 aa)
frdDFumarate reductase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdBSuccinate dehydrogenase and fumarate reductase iron-sulfur protein; Locus tag in AE006468 is STM4342; frdB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdAFumarate reductase, flavoprotein subunit; Locus tag in AE006468 is STM4343; frdA. (596 aa)
EHY67350.1acyl-CoA dehydrogenase protein; Locus tag in AE006468 is STM4377; aidB. (540 aa)
wecCNucleotide sugar dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
fabVShort-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (374 aa)
cobAuroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (457 aa)
dusBTIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (281 aa)
EHY68819.12,4-dienoyl-CoA reductase; KEGG: sea:SeAg_B3406 0. FAD/FMN-binding/pyridine nucleotide-disulphide oxidoreductase family protein; K00219 2,4-dienoyl-CoA reductase (NADPH2); Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3219; fadH. (672 aa)
EHY68667.1Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
tyrAChorismate mutase; KEGG: spq:SPAB_03380 6.0e-193 tyrA; bifunctional chorismate mutase/prephenate dehydrogenase; K04092 chorismate mutase K04517; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2669; tyrA. (373 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (308 aa)
EHY71203.1KEGG: sec:SC2204 2.0e-224 yeiA; dihydropyrimidine dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2187; yeiA. (411 aa)
EHY71202.1Pyridine nucleotide-disulfide oxidoreductase; KEGG: eci:UTI89_C2419 4.7e-177 yeiT; putative oxidoreductase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2186. (413 aa)
dusCTIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (312 aa)
fabIOxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: ses:SARI_01263 1.9e-134 enoyl-(acyl carrier protein) reductase; K00208 enoyl-[acyl-carrier protein] reductase I; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM1700; fabI. (262 aa)
EHY70459.1Oxidoreductase, zinc-binding dehydrogenase family protein; KEGG: seg:SG1536 1.4e-184 yncB; putative NADP-dependent oxidoreductase K07119; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1589; yncB. (345 aa)
caiA_1KEGG: dsy:DSY4302 2.8e-115 putative acyl-CoA dehydrogenase; K08297 crotonobetainyl-CoA dehydrogenase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1356; ydiO. (383 aa)
hpaB4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; KEGG: ses:SARI_01904 1.6e-286 hypothetical protein; K00483 4-hydroxyphenylacetate-3-hydroxylase large chain; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1099; hpaB. (520 aa)
pyrDDihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa)
EHY69756.1KEGG: stm:STM0857 2.5e-210 putative acyl-CoA dehydrogenase K00249; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0857. (387 aa)
sdhBKEGG: spt:SPA2008 2.0e-130 sdhB; succinate dehydrogenase iron-sulfur subunit K00240; Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM0735; sdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa)
hemGKEGG: ses:SARI_03672 1.3e-94 hemG; protoporphyrinogen oxidase; K00230 protoporphyrinogen oxidase; locus tag in AE006468 is STM3987; hemG. (181 aa)
sdhDSuccinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
sdhCKEGG: sed:SeD_A0826 6.5e-45 sdhC; succinate dehydrogenase cytochrome b556 large membrane subunit; K00241 succinate dehydrogenase cytochrome b-556 subunit; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM0732; sdhC. (95 aa)
dhbAKEGG: ses:SARI_02338 6.4e-125 2,3-dihydroxybenzoate-2,3-dehydrogenase; K00216 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM0598; entA. (251 aa)
fadEKEGG: stm:STM0309 0. fadE; acyl-CoA dehydrogenase K06445; Psort location: CytoplasmicMembrane, score: 9.93; locus tag in AE006468 is STM0309; yafH. (814 aa)
caiAcrotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. (380 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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