STRINGSTRING
EHY68304.1 EHY68304.1 EHY71669.1 EHY71669.1 EHY71544.1 EHY71544.1 cysM cysM cysK cysK ubiX ubiX EHY71414.1 EHY71414.1 EHY71114.1 EHY71114.1 cmoB cmoB kdsA kdsA cobO cobO EHY70312.1 EHY70312.1 EHY70286.1 EHY70286.1 aroH aroH aroA aroA aroG aroG nadA nadA selU selU cyoE cyoE ispA ispA ribH ribH uppS uppS speE speE EHY68470.1 EHY68470.1 metK metK EHY68838.1 EHY68838.1 EHY68884.1 EHY68884.1 EHY68893.1 EHY68893.1 murA murA hemC hemC menA menA EHY67714.1 EHY67714.1 thiE thiE ubiA ubiA miaA miaA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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textmining
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EHY68304.13-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (356 aa)
EHY71669.1DTW domain protein; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2650; yfiP. (232 aa)
EHY71544.1cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: sea:SeAg_B2612 6.3e-134 eutT; ethanolamine utilization cobalamin adenosyltransferase K04032; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2467; eutT. (267 aa)
cysMCysteine synthase B; KEGG: sea:SeAg_B2585 1.3e-151 cysM; cysteine synthase B K12339; locus tag in AE006468 is STM2440; cysM; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa)
cysKCysteine synthase A; KEGG: see:SNSL254_A2623 1.7e-165 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2430; cysK; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (189 aa)
EHY71414.1KEGG: bur:Bcep18194_B2348 5.2e-52 glutathione S-transferase-like protein K00799; locus tag in AE006468 is STM2348; yfcF. (214 aa)
EHY71114.1N-acetylneuraminate synthase; KEGG: eck:EC55989_2295 2.0e-155 NnaB K01654; Psort location: Cytoplasmic, score: 8.96. (346 aa)
cmoBPutative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (323 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; KEGG: ses:SARI_01181 1.1e-147 2-dehydro-3-deoxyphosphooctonate aldolase; K01627 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1772; kdsA; Belongs to the KdsA family. (284 aa)
cobOcob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (196 aa)
EHY70312.1Glutathione S-transferase protein; KEGG: seh:SeHA_C1621 2.7e-103 gst; glutathionine S-transferase K00799; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1451; gst; Belongs to the GST superfamily. (201 aa)
EHY70286.1KEGG: spq:SPAB_01898 6.5e-109 riboflavin synthase subunit alpha; K00793 riboflavin synthase alpha chain; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1426; ribE. (213 aa)
aroH3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (348 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (399 aa)
aroG3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (393 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (347 aa)
selUtRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain. (362 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (295 aa)
ispAPolyprenyl synthetase; KEGG: sew:SeSA_A0483 1.6e-151 ispA; geranyltranstransferase K00795; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0423; ispA; Belongs to the FPP/GGPP synthase family. (299 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (156 aa)
uppSDi-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (229 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (286 aa)
EHY68470.13-octaprenyl-4-hydroxybenzoate carboxy-lyase; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase. (195 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (388 aa)
EHY68838.1Glutathione S-transferase protein; KEGG: ebd:ECBD_0637 5.0e-173 glutathione transferase K07393; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3233; yqjG. (328 aa)
EHY68884.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (282 aa)
EHY68893.1Polyprenyl synthetase; KEGG: sec:SC3243 1.2e-201 ispB; octaprenyl diphosphate synthase; K02523 octaprenyl-diphosphate synthase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3305; ispB; Belongs to the FPP/GGPP synthase family. (498 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa)
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (313 aa)
EHY67714.1O-succinylhomoserine (thiol)-lyase; KEGG: sew:SeSA_A4317 3.7e-200 metB; cystathionine gamma-synthase K01739; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4100; metB. (386 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa)
ubiA4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (290 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (301 aa)
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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