(24 nodes) Bacterial-type flagellum organization network (Salmonella enterica houtenae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	flgA	Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa)
	flgD	Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein. (232 aa)
	flgJ	KEGG: ecc:c1350 3.9e-134 flgJ; flagellar rod assembly protein/muramidase FlgJ K02395; Psort location: Periplasmic, score: 10.00; locus tag in AE006468 is STM1182; flgJ. (316 aa)
	flgK	Flagellar hook-associated protein FlgK; Psort location: Extracellular, score: 9.96; locus tag in AE006468 is STM1183; flgK. (553 aa)
	flhe	FlhE protein; Locus tag in AE006468 is STM1912; flhE. (130 aa)
	flhA	Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (692 aa)
	flhB	Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (383 aa)
	flhC	Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (192 aa)
	flhD	Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (81 aa)
	fliS	Flagellar protein FliS; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1961; fliS. (135 aa)
	fliT	Flagellar protein; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (122 aa)
	fliH	Flagellar assembly protein FliH; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1971; fliH. (235 aa)
	fliI	Flagellar protein export ATPase FliI; KEGG: sed:SeD_A1270 1.0e-238 fliI; flagellum-specific ATP synthase K02412; Psort location: Cytoplasmic, score: 9.12; locus tag in AE006468 is STM1972; fliI. (456 aa)
	fliJ	Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (147 aa)
	EHY70998.1	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK. (406 aa)
	fliO	Flagellar biosynthetic protein FliO; KEGG: gtn:GTNG_1394 0.0012 subunit I of b(o/a)3-type cytochrome c oxidase; K02274 cytochrome c oxidase subunit I; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM1978; fliO. (125 aa)
	flgN	FlgN protein; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1171; flgN. (130 aa)
	fliP	Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (245 aa)
	fliQ	Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (83 aa)
	fliR	Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (264 aa)
	EHY68682.1	Hypothetical protein. (143 aa)
	bax	KEGG: cja:CJA_3125 1.5e-22 acm73A; endo-beta-N-acetylglucosaminidase, putative, acm73A K03796; locus tag in AE006468 is STM3663; bax. (190 aa)
	frdC	Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
	flgM	Anti-sigma-28 factor, FlgM; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1172; flgM. (97 aa)

Your Current Organism:

Salmonella enterica houtenae

NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHY70998.1	flgA	SEHO0A_02073	SEHO0A_01059	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	0.890
EHY70998.1	flgD	SEHO0A_02073	SEHO0A_01063	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.	0.993
EHY70998.1	flgJ	SEHO0A_02073	SEHO0A_01069	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	KEGG: ecc:c1350 3.9e-134 flgJ; flagellar rod assembly protein/muramidase FlgJ K02395; Psort location: Periplasmic, score: 10.00; locus tag in AE006468 is STM1182; flgJ.	0.989
EHY70998.1	flgK	SEHO0A_02073	SEHO0A_01070	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar hook-associated protein FlgK; Psort location: Extracellular, score: 9.96; locus tag in AE006468 is STM1183; flgK.	0.992
EHY70998.1	flgM	SEHO0A_02073	SEHO0A_01058	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Anti-sigma-28 factor, FlgM; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1172; flgM.	0.923
EHY70998.1	flgN	SEHO0A_02073	SEHO0A_01057	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	FlgN protein; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1171; flgN.	0.969
EHY70998.1	flhA	SEHO0A_02073	SEHO0A_01941	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.	0.964
EHY70998.1	flhB	SEHO0A_02073	SEHO0A_01942	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.	0.975
EHY70998.1	flhC	SEHO0A_02073	SEHO0A_01953	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.	0.464
EHY70998.1	flhD	SEHO0A_02073	SEHO0A_01954	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.	0.447
EHY70998.1	flhe	SEHO0A_02073	SEHO0A_01940	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	FlhE protein; Locus tag in AE006468 is STM1912; flhE.	0.631
EHY70998.1	fliH	SEHO0A_02073	SEHO0A_02070	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar assembly protein FliH; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1971; fliH.	0.996
EHY70998.1	fliI	SEHO0A_02073	SEHO0A_02071	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar protein export ATPase FliI; KEGG: sed:SeD_A1270 1.0e-238 fliI; flagellum-specific ATP synthase K02412; Psort location: Cytoplasmic, score: 9.12; locus tag in AE006468 is STM1972; fliI.	0.988
EHY70998.1	fliJ	SEHO0A_02073	SEHO0A_02072	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.	0.998
EHY70998.1	fliO	SEHO0A_02073	SEHO0A_02077	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar biosynthetic protein FliO; KEGG: gtn:GTNG_1394 0.0012 subunit I of b(o/a)3-type cytochrome c oxidase; K02274 cytochrome c oxidase subunit I; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM1978; fliO.	0.994
EHY70998.1	fliP	SEHO0A_02073	SEHO0A_02078	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.	0.964
EHY70998.1	fliQ	SEHO0A_02073	SEHO0A_02079	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.	0.955
EHY70998.1	fliR	SEHO0A_02073	SEHO0A_02080	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.	0.970
EHY70998.1	fliS	SEHO0A_02073	SEHO0A_02059	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar protein FliS; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1961; fliS.	0.980
EHY70998.1	fliT	SEHO0A_02073	SEHO0A_02060	Flagellar hook-length control protein; KEGG: msl:Msil_3820 0.0057 H+transporting two-sector ATPase B/B' subunit; K02109 F-type H+-transporting ATPase subunit b; Psort location: Extracellular, score: 10.00; locus tag in AE006468 is STM1974; fliK.	Flagellar protein; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.	0.758