STRINGSTRING
ampD ampD mtnN mtnN dgt dgt EHY69199.1 EHY69199.1 EHY69244.1 EHY69244.1 EHY69247.1 EHY69247.1 EHY69464.1 EHY69464.1 EHY69470.1 EHY69470.1 nagB nagB EHY69800.1 EHY69800.1 amiD_2 amiD_2 nanE nanE EHY70091.1 EHY70091.1 EHY70092.1 EHY70092.1 chbG chbG mpaA mpaA EHY70934.1 EHY70934.1 cdd cdd EHY71275.1 EHY71275.1 EHY71312.1 EHY71312.1 SBOV24401 SBOV24401 amiA amiA murQ murQ amiD_1 amiD_1 surE surE mazG mazG amiC amiC yqfB yqfB kbaZ kbaZ kbaY kbaY nanK nanK nanE-2 nanE-2 nanA nanA EHY67919.1 EHY67919.1 gpsA gpsA dut dut EHY68219.1 EHY68219.1 gppA gppA EHY68277.1 EHY68277.1 EHY67601.1 EHY67601.1 EHY67602.1 EHY67602.1 EHY67603.1 EHY67603.1 EHY67638.1 EHY67638.1 amiB amiB EHY67480.1 EHY67480.1 deoC deoC deoB deoB deoD deoD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ampDProtein AmpD; KEGG: ecf:ECH74115_0116 1.2e-89 ampD; N-acetyl-anhydromuranmyl-L-alanine amidase K03806; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0146; ampD. (187 aa)
mtnNMTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] (232 aa)
dgtPutative dGTPase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (505 aa)
EHY69199.1Chitinase class I; KEGG: swd:Swoo_1101 5.7e-165 chitinase; Psort location: Periplasmic, score: 9.84; locus tag in AE006468 is STM0233. (587 aa)
EHY69244.1Hypothetical protein; Psort location: Periplasmic, score: 9.83. (805 aa)
EHY69247.1Hypothetical protein. (733 aa)
EHY69464.1DNA transfer protein gp20 family protein; KEGG: bqu:BQ01690 0.0047 guaB; inosine 5'-monophosphate dehydrogenase K00088; Psort location: Extracellular, score: 9.64. (456 aa)
EHY69470.1Polysaccharide lyase family 8, super-sandwich domain protein; Broad-specificity glycosaminoglycan lyase. (1061 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
EHY69800.1Hypothetical protein; KEGG: cti:RALTA_A2225 5.2e-20 putative chitinase. (181 aa)
amiD_2KEGG: sea:SeAg_B0931 3.8e-143 N-acetylmuramoyl-L-alanine amidase AmiD K11066; Psort location: CytoplasmicMembrane, score: 9.76; locus tag in AE006468 is STM0931; ybjR. (276 aa)
nanEHypothetical protein; KEGG: ecw:EcE24377A_3705 3.6e-33 N-acetylmannosamine-6-phosphate 2-epimerase; K01788 N-acylglucosamine-6-phosphate 2-epimerase; locus tag in AE006468 is STM1129. (140 aa)
EHY70091.1Hypothetical protein; KEGG: cti:RALTA_A2225 2.7e-07 putative chitinase. (72 aa)
EHY70092.1Hypothetical protein; KEGG: cti:RALTA_A2225 1.5e-20 putative chitinase. (123 aa)
chbGYdjC-like protein; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the [...] (252 aa)
mpaAZinc carboxypeptidase; KEGG: eci:UTI89_C1597 8.7e-121 ycjI; murein peptide amidase A; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1680; ycjI. (242 aa)
EHY70934.1Hypothetical protein; KEGG: cti:RALTA_A2225 7.5e-28 putative chitinase. (204 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (294 aa)
EHY71275.1Hypothetical protein; KEGG: cti:RALTA_A2225 1.0e-30 putative chitinase. (205 aa)
EHY71312.1Phage lysozyme; KEGG: har:HEAR2266 5.5e-16 putative lysozyme (lysis protein) (muramidase) (endolysin); K01185 lysozyme. (161 aa)
SBOV24401Hypothetical protein; Locus tag in AE006468 is STM2375. (122 aa)
amiAKEGG: sed:SeD_A2816 4.0e-148 amiA; N-acetylmuramoyl-L-alanine amidase I K01448; locus tag in AE006468 is STM2450; amiA. (289 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (297 aa)
amiD_1KEGG: eic:NT01EI_3435 1.8e-120 N-acetylmuramoyl-L-alanine amidase AmiD; Psort location: Cytoplasmic, score: 9.97. (256 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. (250 aa)
mazGMazG family protein; KEGG: sea:SeAg_B3087 2.7e-133 mazG; nucleoside triphosphate pyrophosphohydrolase; K02428 nucleoside-triphosphate pyrophosphatase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2954; mazG. (263 aa)
amiCKEGG: set:SEN2833 3.8e-214 amiC; N-acetylmuramoyl-L-alanine amidase K01448; locus tag in AE006468 is STM2991; amiC. (417 aa)
yqfBASCH domain protein; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3050; yqfB; Belongs to the UPF0267 family. (103 aa)
kbaZD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity. (435 aa)
kbaYClass II aldolase, tagatose bisphosphate family protein; KEGG: ses:SARI_04361 1.6e-144 kbaY; tagatose-bisphosphate aldolase; K08302 tagatose 1,6-diphosphate aldolase; Psort location: Cytoplasmic, score: 8.96. (290 aa)
nanKROK family protein; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (291 aa)
nanE-2Putative N-acetylmannosamine-6-P epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (229 aa)
nanAN-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (297 aa)
EHY67919.1Hypothetical protein; KEGG: pct:PC1_0580 1.1e-12 lysozyme; locus tag in AE006468 is STM3605. (116 aa)
gpsAKEGG: seh:SeHA_C4025 3.7e-177 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; K00057 glycerol-3-phosphate dehydrogenase (NAD(P)+); Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3700; gpsA; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
dutdUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (152 aa)
EHY68219.1Phosphorylase family protein; KEGG: sea:SeAg_B4137 3.5e-110 uridine phosphorylase; K00757 uridine phosphorylase; Psort location: Cytoplasmic, score: 9.26. (221 aa)
gppAPpx/GppA phosphatase family protein; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. (499 aa)
EHY68277.1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (253 aa)
EHY67601.1N-acylglucosamine 2-epimerase; Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF). (413 aa)
EHY67602.1Deoxyribose-phosphate aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family. (292 aa)
EHY67603.1NAD binding domain of 6-phosphogluconate dehydrogenase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (298 aa)
EHY67638.1Putative fructose-1,6-bisphosphate aldolase; KEGG: kpe:KPK_5486 4.5e-133 fructose-bisphosphate aldolase, class II family; K01624 fructose-bisphosphate aldolase, class II; Psort location: Cytoplasmic, score: 8.96. (280 aa)
amiBN-acetylmuramoyl-L-alanine amidase; Locus tag in AE006468 is STM4358; amiB. (438 aa)
EHY67480.1Polysaccharide lyase family 8, super-sandwich domain protein. (785 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. (271 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa)
deoDPurine nucleoside phosphorylase; Locus tag in AE006468 is STM4570; deoD. (239 aa)
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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