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| | fbp | Fructose-1,6-bisphosphatase; Locus tag in AE006468 is STM4415; fbp; Belongs to the FBPase class 1 family. (332 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa) |
| | ilvA | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) |
| | fabV | Short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (374 aa) |
| | fadB | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (771 aa) |
| | EHY67603.1 | NAD binding domain of 6-phosphogluconate dehydrogenase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (298 aa) |
| | hydN_1 | 4Fe-4S binding domain protein; KEGG: eci:UTI89_C4115 4.9e-63 ysaA, yiaI, b3573; putative electron transport protein YsaA; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3666; ysaA. (157 aa) |
| | kdgK | Kinase, PfkB family; KEGG: sty:STY4191 3.3e-160 kdgK; 2-dehydro-3-deoxygluconokinase; K00874 2-dehydro-3-deoxygluconokinase; locus tag in AE006468 is STM3612; kdgK. (309 aa) |
| | nikR | Nickel-responsive transcriptional regulator NikR; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. (133 aa) |
| | gntK | Shikimate kinase; KEGG: sty:STY4269 2.9e-81 gntK; gluconate kinase 1 K00851; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3542; gntK. (164 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | EHY67819.1 | KEGG: sew:SeSA_A3680 6.6e-116 rpe; ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3483; rpe. (225 aa) |
| | EHY67800.1 | Phosphoribulokinase / Uridine kinase family protein; KEGG: spt:SPA3330 2.0e-155 prkB; phosphoribulokinase; K00855 phosphoribulokinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3464; prkB. (289 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | EHY68849.1 | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (329 aa) |
| | tdcG | KEGG: sek:SSPA2901 4.0e-235 L-serine dehydratase; K01752 L-serine dehydratase; locus tag in AE006468 is STM3240; tdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | hybA | Tat pathway signal sequence; KEGG: eci:UTI89_C3418 4.1e-178 hybA; hydrogenase 2 protein HybA; Psort location: CytoplasmicMembrane, score: 9.99; locus tag in AE006468 is STM3149; hybA. (328 aa) |
| | tkt-2 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa) |
| | EHY68640.1 | Transketolase, thiamine diphosphate binding domain protein; KEGG: kpu:KP1_1544 7.7e-129 putative transketolase N-terminal subunit; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96. (276 aa) |
| | EHY68639.1 | Transketolase protein; KEGG: efe:EFER_2514 6.5e-132 putative transketolase C-terminal section; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96. (312 aa) |
| | pgk | Phosphoglycerate kinase; KEGG: seh:SeHA_C3306 3.5e-197 pgk; phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3069; pgk. (387 aa) |
| | fba | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | EHY68623.1 | KEGG: ses:SARI_04585 0. methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase; Psort location: Cytoplasmic, score: 8.96. (714 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa) |
| | serA | KEGG: spq:SPAB_03816 2.1e-213 D-3-phosphoglycerate dehydrogenase; K00058 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3062; serA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa) |
| | sdhE | TPR repeat region; KEGG: lhk:LHK_02418 2.0e-05 sdhB; SdhB; locus tag in AE006468 is STM3047; ygfY. (88 aa) |
| | thlA_1 | KEGG: sei:SPC_3078 3.1e-205 yqeF; acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3019; yqeF; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | sdaB | KEGG: see:SNSL254_A3194 1.2e-240 L-serine ammonia-lyase K01752; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2971; sdaB; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | EHY68511.1 | Hypothetical protein; KEGG: sbo:SBO_2660 4.3e-32 eno; phosphopyruvate hydratase K01689; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM2952; eno. (75 aa) |
| | hycB | 4Fe-4S binding domain protein; Locus tag in AE006468 is STM2852; hycB. (202 aa) |
| | hydN_2 | 4Fe-4S binding domain protein; Locus tag in AE006468 is STM2843; hydN. (181 aa) |
| | yfhH | Transcriptional regulator, RpiR family; KEGG: hip:CGSHiEE_02570 5.5e-25 N-acetylmannosamine kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2572; yfhH. (282 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | arsC | Arsenate reductase; KEGG: sty:STY2736 1.1e-56 putative arsenate reductase (arsenical pump modifier); K00537 arsenate reductase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2495; yfgD. (119 aa) |
| | yffB | Transcriptional regulator, Spx/MgsR family; KEGG: bme:BMEI1557 4.0e-29 arsenate reductase K00540; locus tag in AE006468 is STM2482; yffB; Belongs to the ArsC family. (118 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa) |
| | EHY71550.1 | Malate dehydrogenase; KEGG: sew:SeSA_A2705 0. maeB; malic enzyme K00029; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2472; maeB. (759 aa) |
| | cysK | Cysteine synthase A; KEGG: see:SNSL254_A2623 1.7e-165 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2430; cysK; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) |
| | glk | Glucokinase; KEGG: sec:SC2406 1.5e-171 glk; glucokinase K00845; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2403; glk; Belongs to the bacterial glucokinase family. (321 aa) |
| | fadJ | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa) |
| | tktA_2 | Transketolase, thiamine diphosphate binding domain protein; KEGG: ses:SARI_00559 5.9e-147 hypothetical protein; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2341. (276 aa) |
| | EHY71406.1 | Transketolase protein; KEGG: sea:SeAg_B2481 4.6e-163 transketolase domain protein; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2340. (317 aa) |
| | EHY67616.1 | KEGG: ses:SARI_03632 1.1e-113 formate dehydrogenase-O subunit gamma; K00127 formate dehydrogenase, gamma subunit; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM4035; fdoI. (211 aa) |
| | EHY71403.1 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | EHY71268.1 | Phage prohead protease, HK97 family; Psort location: Cytoplasmic, score: 8.96. (200 aa) |
| | fghA | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (285 aa) |
| | fbaB | Deoxyribose-phosphate aldolase; KEGG: spt:SPA0711 1.1e-184 fbaB; fructose-bisphosphate aldolase K01623; locus tag in AE006468 is STM2141; fbaB. (350 aa) |
| | wcaB | Bacterial transferase hexapeptide repeat protein; KEGG: spq:SPAB_00916 4.0e-84 putative colanic acid biosynthesis acetyltransferase WcaB; K03819 putative colanic acid biosynthesis acetyltransferase WcaB; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM2114; wcaB; Belongs to the transferase hexapeptide repeat family. (162 aa) |
| | EHY71101.1 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | EHY71060.1 | Molybdenum cofactor synthesis domain protein; KEGG: psp:PSPPH_2159 2.0e-105 isocitrate/isopropylmalate family dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97. (725 aa) |
| | EHY70889.1 | ribose/Galactose Isomerase; KEGG: cja:CJA_2965 3.3e-82 rpiB2; sugar-phosphate isomerase; locus tag in AE006468 is STM1933. (212 aa) |
| | pyk | Pyruvate kinase; Locus tag in AE006468 is STM1888; pykA; Belongs to the pyruvate kinase family. (480 aa) |
| | ybbH_1 | Transcriptional regulator, RpiR family; Locus tag in AE006468 is STM1887; yebK. (289 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) |
| | eda | KHG/KDPG aldolase; Locus tag in AE006468 is STM1884; eda. (213 aa) |
| | EHY70772.1 | L-serine ammonia-lyase; KEGG: spq:SPAB_01388 7.4e-243 hypothetical protein; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1826; sdaA. (454 aa) |
| | EHY70743.1 | KEGG: sek:SSPA1002 6.2e-159 ldcA; L,D-carboxypeptidase A; K01297 muramoyltetrapeptide carboxypeptidase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1800; ycgQ. (304 aa) |
| | gdhA_1 | KEGG: see:SNSL254_A1932 2.8e-227 glutamate dehydrogenase K00261; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1795; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa) |
| | nifJ | KEGG: sew:SeSA_A1770 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM1651; nifJ. (1174 aa) |
| | EHY70532.1 | S-(hydroxymethyl)glutathione synthase; Locus tag in AE006468 is STM1643. (149 aa) |
| | EHY70515.1 | KEGG: sea:SeAg_B1530 1.4e-202 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; K00001 alcohol dehydrogenase K00121; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1627; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa) |
| | EHY70505.1 | Hypothetical protein; KEGG: stt:t1526 1.6e-27 epimerase K01795; locus tag in AE006468 is STM1617. (61 aa) |
| | EHY70442.1 | S-(hydroxymethyl)glutathione synthase; KEGG: xcb:XC_0776 0.0025 glutathione-dependent formaldehyde-activating enzyme; K03396 S-(hydroxymethyl)glutathione synthase; locus tag in AE006468 is STM1573. (146 aa) |
| | fdnG | KEGG: set:SEN1485 0. fdnG; formate dehydrogenase, nitrate-inducible, major subunit (formate dehydrogenase-n alpha subunit) (fdh-n alpha subunit) (anaerobic formate dehydrogenase major subunit) K08348; Psort location: Periplasmic, score: 10.00; locus tag in AE006468 is STM1570; fdnG. (803 aa) |
| | sfcA | Malic enzyme, NAD binding domain protein; KEGG: ses:SARI_01403 3.5e-291 malate dehydrogenase; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM1566; sfcA. (546 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | EHY70332.1 | Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (525 aa) |
| | rsxC | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (669 aa) |
| | pykF | Pyruvate kinase; KEGG: sei:SPC_2351 8.4e-242 pykF; pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1378; pykF. (470 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa) |
| | pfkB | Hexose kinase, 1-phosphofructokinase family; KEGG: sew:SeSA_A1423 3.1e-157 pfkB; 6-phosphofructokinase 2 K00850; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1326; pfkB; Belongs to the carbohydrate kinase PfkB family. (310 aa) |
| | EHY70189.1 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (750 aa) |
| | EHY70161.1 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: sek:SSPA1445 3.4e-174 glyceraldehyde 3-phosphate dehydrogenase A; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 10.00; locus tag in AE006468 is STM1290; gapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | EHY70079.1 | Isocitrate dehydrogenase, NADP-dependent; KEGG: spq:SPAB_02276 6.2e-223 isocitrate dehydrogenase; K00031 isocitrate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1238; icdA. (416 aa) |
| | EHY69957.1 | Transcriptional regulator, RpiR family; KEGG: hip:CGSHiEE_02570 3.9e-79 N-acetylmannosamine kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1127. (293 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
| | EHY69755.1 | Hypothetical protein. (87 aa) |
| | pgl | Putative 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa) |
| | EHY69661.1 | KEGG: shl:Shal_2748 5.4e-144 acetyl-CoA acetyltransferase K00626; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa) |
| | gpmA | Phosphoglycerate mutase 1 family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) |
| | sucC | succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa) |
| | sucA | KEGG: sea:SeAg_B0769 0. sucA; 2-oxoglutarate dehydrogenase E1 component K00164; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0736; sucA. (933 aa) |
| | sdhB | KEGG: spt:SPA2008 2.0e-130 sdhB; succinate dehydrogenase iron-sulfur subunit K00240; Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM0735; sdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa) |
| | sdhA | KEGG: spt:SPA2009 0. sdhA; succinate dehydrogenase flavoprotein subunit K00239; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM0734; sdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhD | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | sdhC | KEGG: sed:SeD_A0826 6.5e-45 sdhC; succinate dehydrogenase cytochrome b556 large membrane subunit; K00241 succinate dehydrogenase cytochrome b-556 subunit; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM0732; sdhC. (95 aa) |
| | gltA | Citrate (Si)-synthase; KEGG: sew:SeSA_A0887 1.4e-230 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0730; gltA. (427 aa) |
| | tcuA | Precorrin 3B synthase CobZ; KEGG: bpt:Bpet0773 1.3e-211 tricarballylate dehydrogenase; locus tag in AE006468 is STM0691. (467 aa) |
| | ybdR_1 | Oxidoreductase, zinc-binding dehydrogenase family protein; KEGG: seh:SeHA_C0728 2.1e-220 S-(hydroxymethyl)glutathione dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) (fdh) (faldh); Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0615; ybdR. (412 aa) |
| | EHY69515.1 | Hypothetical protein; Locus tag in AE006468 is STM0601; ybdD. (65 aa) |
| | EHY69475.1 | KEGG: eci:UTI89_C0327 1.2e-171 ykgC; pyridine nucleotide-disulfide oxidoreductase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM0564. (441 aa) |
| | folD | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | EHY69381.1 | Pyridoxal-phosphate dependent enzyme; KEGG: set:SEN0440 3.4e-190 putative lyase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0458. (351 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | acnB | Aconitate hydratase 2; KEGG: ses:SARI_02835 0. bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; K01682 aconitate hydratase 2; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0158; acnB; Belongs to the aconitase/IPM isomerase family. (839 aa) |
| | lpdA | Dihydrolipoyl dehydrogenase; KEGG: ses:SARI_02839 1.3e-252 dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0154; lpdA. (475 aa) |
| | aceF | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (625 aa) |
| | aceE | Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | caiD | carnitinyl-CoA dehydratase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. (261 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | EHY68003.1 | KEGG: sec:SC3622 1.1e-143 cysE; serine acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3699; cysE; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | gpmB | Phosphoglycerate mutase family protein; Locus tag in AE006468 is STM4585; gpmB; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | serB | Phosphoserine phosphatase SerB; Locus tag in AE006468 is STM4578; serB. (294 aa) |
| | EHY67514.1 | Hypothetical protein; Locus tag in AE006468 is STM4531; yjiX. (64 aa) |
| | EHY67444.1 | Carbohydrate kinase, thermoresistant glucokinase family protein; Locus tag in AE006468 is STM4485; idnK. (74 aa) |
| | arcC | Carbamate kinase; Locus tag in AE006468 is STM4466; Belongs to the carbamate kinase family. (310 aa) |
| | vapC | Toxin-antitoxin system, toxin component, PIN family; Toxic component of a toxin-antitoxin (TA) system. A site- specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Its toxic effects are neutralized by expression of cognate antitoxin VapB; Belongs to the PINc/VapC protein family. (138 aa) |
| | fdxH-2 | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa) |
| | fdnG-2 | KEGG: set:SEN3826 0. fdoG; formate dehydrogenase-O, major subunit K00123; Psort location: Periplasmic, score: 10.00; locus tag in AE006468 is STM4037; fdoG; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (804 aa) |
| | EHY67635.1 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (326 aa) |
| | EHY67641.1 | Hypothetical protein; KEGG: mlo:mlr3412 2.5e-43 glucokinase; K00845 glucokinase. (174 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | glpX | Fructose-1,6-bisphosphatase, class II; KEGG: stt:t3533 2.1e-167 glpX; fructose 1,6-bisphosphatase II K02446; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4085; glpX. (325 aa) |
| | metF | KEGG: stt:t3511 5.8e-156 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM4105; metF. (296 aa) |
| | fsa | Fructose-6-phosphate aldolase; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily. (220 aa) |
| | ppc | Phosphoenolpyruvate carboxykinase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (883 aa) |
| | EHY67154.1 | Malate synthase A; Locus tag in AE006468 is STM4183; aceB; Belongs to the malate synthase family. (534 aa) |
| | EHY67155.1 | Isocitrate lyase; Locus tag in AE006468 is STM4184; aceA. (434 aa) |
| | pgi | Glucose-6-phosphate isomerase; Locus tag in AE006468 is STM4221; pgi; Belongs to the GPI family. (549 aa) |
| | acs | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa) |
| | EHY67237.1 | Formate dehydrogenase, alpha subunit; Locus tag in AE006468 is STM4285; fdhF; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (559 aa) |
| | fumB | Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | frdD | Fumarate reductase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa) |
| | frdC | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa) |
| | frdB | Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Locus tag in AE006468 is STM4342; frdB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa) |
| | frdA | Fumarate reductase, flavoprotein subunit; Locus tag in AE006468 is STM4343; frdA. (596 aa) |
