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| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa) |
| | EHY68003.1 | KEGG: sec:SC3622 1.1e-143 cysE; serine acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3699; cysE; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | yhhQ | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (221 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (161 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (342 aa) |
| | EHY67819.1 | KEGG: sew:SeSA_A3680 6.6e-116 rpe; ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3483; rpe. (225 aa) |
| | argD | N-succinyldiaminopimelate- aminotransferase/acetylornithine transaminase protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (390 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | yhdE | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa) |
| | EHY68919.1 | KEGG: spq:SPAB_04154 4.9e-253 gltD; glutamate synthase subunit beta; K00266 glutamate synthase (NADPH/NADH) small chain; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3331; gltD. (472 aa) |
| | EHY68918.1 | Class II glutamine amidotransferase; KEGG: stt:t3247 0. gltB; glutamate synthase subunit alpha K00265; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3330; gltB. (1486 aa) |
| | sfsB | Putative sugar fermentation stimulation protein B; Locus tag in AE006468 is STM3306; nlp. (95 aa) |
| | argG | KEGG: ses:SARI_04334 4.0e-235 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3290; argG; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (447 aa) |
| | yhbQ | GIY-YIG catalytic domain protein; KEGG: eli:ELI_05635 1.3e-05 rRNA methylase; K02533 tRNA/rRNA methyltransferase; locus tag in AE006468 is STM3271; yhbQ; Belongs to the UPF0213 family. (120 aa) |
| | EHY68849.1 | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (329 aa) |
| | gpmA | Phosphoglycerate mutase 1 family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | EHY69716.1 | Glycosyl transferase family, helical bundle domain protein; KEGG: mms:mma_0486 6.3e-63 trpD2; glycosyl transferase family protein; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0822; ybiB. (324 aa) |
| | EHY69810.1 | Glycine hydroxymethyltransferase; KEGG: see:SNSL254_A0969 3.9e-173 ltaE; low-specificity L-threonine aldolase K01620; locus tag in AE006468 is STM0934; ltaA. (333 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (399 aa) |
| | aspC | Aminotransferase, class I/II; KEGG: spq:SPAB_02515 1.6e-208 aromatic amino acid aminotransferase; K00813 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0998; aspC. (396 aa) |
| | sxy | TfoX protein; KEGG: hip:CGSHiEE_09150 0.00062 def; peptide deformylase K07343; locus tag in AE006468 is STM1072; yccR. (201 aa) |
| | EHY69957.1 | Transcriptional regulator, RpiR family; KEGG: hip:CGSHiEE_02570 3.9e-79 N-acetylmannosamine kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1127. (293 aa) |
| | ycdX | KEGG: vfi:VF_A0065 1.5e-52 putative hydrolase K04477; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1136; ycdX; Belongs to the PHP family. (245 aa) |
| | rimJ | KEGG: ses:SARI_01830 4.7e-106 ribosomal-protein-S5-alanine N-acetyltransferase; K03790 ribosomal-protein-alanine N-acetyltransferase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1167; rimJ. (194 aa) |
| | EHY70021.1 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (194 aa) |
| | EHY70079.1 | Isocitrate dehydrogenase, NADP-dependent; KEGG: spq:SPAB_02276 6.2e-223 isocitrate dehydrogenase; K00031 isocitrate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1238; icdA. (416 aa) |
| | EHY70096.1 | Hypothetical protein. (51 aa) |
| | EHY70097.1 | Hypothetical protein. (58 aa) |
| | EHY70098.1 | Transposase, IS116/IS110/IS902 family. (324 aa) |
| | aroQ | Putative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (181 aa) |
| | EHY70161.1 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: sek:SSPA1445 3.4e-174 glyceraldehyde 3-phosphate dehydrogenase A; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 10.00; locus tag in AE006468 is STM1290; gapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | pfkB | Hexose kinase, 1-phosphofructokinase family; KEGG: sew:SeSA_A1423 3.1e-157 pfkB; 6-phosphofructokinase 2 K00850; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1326; pfkB; Belongs to the carbohydrate kinase PfkB family. (310 aa) |
| | aroH | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (348 aa) |
| | aroD | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (233 aa) |
| | pykF | Pyruvate kinase; KEGG: sei:SPC_2351 8.4e-242 pykF; pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1378; pykF. (470 aa) |
| | EHY70327.1 | Maltose regulon modulator MalY; KEGG: sew:SeSA_A1562 1.8e-207 protein MalY K01760; Psort location: Cytoplasmic, score: 8.96. (390 aa) |
| | EHY70423.1 | Aminotransferase, class I/II; KEGG: set:SEN1498 2.0e-217 putative aminotransferase; K00842 aminotransferase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1557. (400 aa) |
| | rimL | Acetyltransferase, GNAT family; KEGG: sei:SPC_2124 9.8e-90 rimL; ribosomal-protein-serine acetyltransferase; K03817 ribosomal-protein-serine acetyltransferase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1611; rimL. (179 aa) |
| | EHY70498.1 | Transposase; Psort location: Cytoplasmic, score: 8.96. (333 aa) |
| | EHY70505.1 | Hypothetical protein; KEGG: stt:t1526 1.6e-27 epimerase K01795; locus tag in AE006468 is STM1617. (61 aa) |
| | EHY70579.1 | NmrA family protein; KEGG: afm:AFUA_6G00280 1.5e-61 NmrA-like family protein K00224; locus tag in AE006468 is STM1678. (309 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa) |
| | EHY70645.1 | KEGG: set:SEN1311 7.3e-275 trpE; anthranilate synthase component I; K01657 anthranilate synthase component I; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1723; trpE. (520 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (531 aa) |
| | trpF | KEGG: spq:SPAB_01520 6.2e-230 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; K01609 indole-3-glycerol phosphate synthase K01817; locus tag in AE006468 is STM1725; trpC; Belongs to the TrpC family. (452 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | EHY70772.1 | L-serine ammonia-lyase; KEGG: spq:SPAB_01388 7.4e-243 hypothetical protein; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1826; sdaA. (454 aa) |
| | ybbH_1 | Transcriptional regulator, RpiR family; Locus tag in AE006468 is STM1887; yebK. (289 aa) |
| | pyk | Pyruvate kinase; Locus tag in AE006468 is STM1888; pykA; Belongs to the pyruvate kinase family. (480 aa) |
| | EHY70889.1 | ribose/Galactose Isomerase; KEGG: cja:CJA_2965 3.3e-82 rpiB2; sugar-phosphate isomerase; locus tag in AE006468 is STM1933. (212 aa) |
| | EHY71060.1 | Molybdenum cofactor synthesis domain protein; KEGG: psp:PSPPH_2159 2.0e-105 isocitrate/isopropylmalate family dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97. (725 aa) |
| | EHY71073.1 | DNA-binding protein Ner family protein. (73 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (289 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa) |
| | hisC | KEGG: spq:SPAB_00960 1.2e-187 histidinol-phosphate aminotransferase; K00817 histidinol-phosphate aminotransferase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2073; hisC; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa) |
| | hisB | Histidinol-phosphatase; KEGG: sea:SeAg_B2199 2.4e-189 hisB; imidazole glycerol-phosphate dehydratase/histidinol phosphatase K01089; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2074; hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. (355 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisA | KEGG: see:SNSL254_A2255 7.9e-120 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2076; hisA. (245 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | hisI | phosphoribosyl-ATP diphosphatase; KEGG: sew:SeSA_A2306 7.9e-104 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein K11755; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2078; hisI; In the N-terminal section; belongs to the PRA-CH family. (203 aa) |
| | EHY71106.1 | KEGG: gur:Gura_1692 2.6e-82 imidazole glycerol phosphate synthase subunit HisF; K02500 cyclase HisF; Psort location: Cytoplasmic, score: 9.26. (262 aa) |
| | EHY71107.1 | KEGG: vvy:VV0355 1.5e-61 hisH; imidazole glycerol phosphate synthase subunit HisH; K02501 glutamine amidotransferase; Psort location: Cytoplasmic, score: 9.26. (204 aa) |
| | wcaB | Bacterial transferase hexapeptide repeat protein; KEGG: spq:SPAB_00916 4.0e-84 putative colanic acid biosynthesis acetyltransferase WcaB; K03819 putative colanic acid biosynthesis acetyltransferase WcaB; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM2114; wcaB; Belongs to the transferase hexapeptide repeat family. (162 aa) |
| | fbaB | Deoxyribose-phosphate aldolase; KEGG: spt:SPA0711 1.1e-184 fbaB; fructose-bisphosphate aldolase K01623; locus tag in AE006468 is STM2141; fbaB. (350 aa) |
| | EHY71268.1 | Phage prohead protease, HK97 family; Psort location: Cytoplasmic, score: 8.96. (200 aa) |
| | EHY71395.1 | Aminotransferase AlaT; KEGG: sei:SPC_1377 4.6e-218 yfbQ; aspartate aminotransferase; K10907 aminotransferase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2331; yfbQ. (404 aa) |
| | EHY71406.1 | Transketolase protein; KEGG: sea:SeAg_B2481 4.6e-163 transketolase domain protein; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2340. (317 aa) |
| | tktA_2 | Transketolase, thiamine diphosphate binding domain protein; KEGG: ses:SARI_00559 5.9e-147 hypothetical protein; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2341. (276 aa) |
| | EHY71437.1 | Semialdehyde dehydrogenase, dimerization domain protein; KEGG: see:SNSL254_A2557 2.7e-174 aspartate-semialdehyde dehydrogenase family protein; K00133 aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM2369; usg. (337 aa) |
| | EHY71442.1 | Helix-turn-helix protein; Locus tag in AE006468 is STM2374. (82 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | cysK | Cysteine synthase A; KEGG: see:SNSL254_A2623 1.7e-165 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2430; cysK; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) |
| | cysM | Cysteine synthase B; KEGG: sea:SeAg_B2585 1.3e-151 cysM; cysteine synthase B K12339; locus tag in AE006468 is STM2440; cysM; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa) |
| | ypeA | Acetyltransferase, GNAT family; KEGG: eta:ETA_10870 2.8e-60 acetyltransferase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2449; Belongs to the acetyltransferase family. YpeA subfamily. (141 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | yfhH | Transcriptional regulator, RpiR family; KEGG: hip:CGSHiEE_02570 5.5e-25 N-acetylmannosamine kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2572; yfhH. (282 aa) |
| | pheA | Chorismate mutase; KEGG: seg:SG2645 1.3e-199 pheA; bifunctional chorismate mutase/prephenate dehydratase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2667; pheA. (386 aa) |
| | tyrA | Chorismate mutase; KEGG: spq:SPAB_03380 6.0e-193 tyrA; bifunctional chorismate mutase/prephenate dehydrogenase; K04092 chorismate mutase K04517; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2669; tyrA. (373 aa) |
| | EHY68304.1 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (356 aa) |
| | luxS | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa) |
| | EHY68511.1 | Hypothetical protein; KEGG: sbo:SBO_2660 4.3e-32 eno; phosphopyruvate hydratase K01689; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM2952; eno. (75 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | sdaB | KEGG: see:SNSL254_A3194 1.2e-240 L-serine ammonia-lyase K01752; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2971; sdaB; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | argA | Amino-acid N-acetyltransferase; KEGG: stt:t2900 2.1e-229 argA; N-acetylglutamate synthase K00619; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2992; argA; Belongs to the acetyltransferase family. ArgA subfamily. (443 aa) |
| | lysA_1 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | serA | KEGG: spq:SPAB_03816 2.1e-213 D-3-phosphoglycerate dehydrogenase; K00058 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3062; serA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa) |
| | fba | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pgk | Phosphoglycerate kinase; KEGG: seh:SeHA_C3306 3.5e-197 pgk; phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3069; pgk. (387 aa) |
| | EHY68639.1 | Transketolase protein; KEGG: efe:EFER_2514 6.5e-132 putative transketolase C-terminal section; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96. (312 aa) |
| | EHY68640.1 | Transketolase, thiamine diphosphate binding domain protein; KEGG: kpu:KP1_1544 7.7e-129 putative transketolase N-terminal subunit; K00615 transketolase; Psort location: Cytoplasmic, score: 8.96. (276 aa) |
| | tkt-2 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (388 aa) |
| | EHY68700.1 | Transposase; Psort location: Cytoplasmic, score: 8.96. (333 aa) |
| | metC | Cystathionine beta-lyase; KEGG: sea:SeAg_B3335 3.0e-207 metC; cystathionine beta-lyase K01760; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3161; metC. (395 aa) |
| | tdcG | KEGG: sek:SSPA2901 4.0e-235 L-serine dehydratase; K01752 L-serine dehydratase; locus tag in AE006468 is STM3240; tdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | ksgA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (273 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (523 aa) |
| | EHY67434.1 | Hypothetical protein. (44 aa) |
| | EHY69078.1 | KEGG: spq:SPAB_00147 1.0e-300 acetolactate synthase 3 catalytic subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: CytoplasmicMembrane, score: 8.46; locus tag in AE006468 is STM0116; ilvI. (566 aa) |
| | serB | Phosphoserine phosphatase SerB; Locus tag in AE006468 is STM4578; serB. (294 aa) |
| | gpmB | Phosphoglycerate mutase family protein; Locus tag in AE006468 is STM4585; gpmB; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | acnB | Aconitate hydratase 2; KEGG: ses:SARI_02835 0. bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; K01682 aconitate hydratase 2; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0158; acnB; Belongs to the aconitase/IPM isomerase family. (839 aa) |
| | aroG | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (393 aa) |
| | gltA | Citrate (Si)-synthase; KEGG: sew:SeSA_A0887 1.4e-230 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0730; gltA. (427 aa) |
| | asnB | Asparagine synthase; KEGG: spq:SPAB_02863 1.1e-301 asnB; asparagine synthetase B; K01953 asparagine synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0680; asnB. (554 aa) |
| | EHY69517.1 | KEGG: sei:SPC_0615 8.8e-192 ybdL; putative aminotransferase; K10907 aminotransferase; locus tag in AE006468 is STM0603; ybdL. (364 aa) |
| | EHY69381.1 | Pyridoxal-phosphate dependent enzyme; KEGG: set:SEN0440 3.4e-190 putative lyase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0458. (351 aa) |
| | aroL | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (181 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | EHY69249.1 | Transposase; Psort location: Cytoplasmic, score: 8.96. (333 aa) |
| | dapD | KEGG: sed:SeD_A0234 5.6e-142 dapD; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase K00674; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0213; dapD; Belongs to the transferase hexapeptide repeat family. (274 aa) |
| | mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] (232 aa) |
| | thrA | Homoserine dehydrogenase; KEGG: set:SEN0001 0. thrA; bifunctional aspartokinase I/homeserine dehydrogenase I; K12524 bifunctional aspartokinase/homoserine dehydrogenase 1; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0002; thrA; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | EHY68979.1 | Threonine synthase; KEGG: sed:SeD_A0004 1.2e-224 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0004; thrC. (428 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | EHY69079.1 | KEGG: see:SNSL254_A0129 7.2e-78 ilvH; acetolactate synthase, small subunit, isozyme III K01653; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0117; ilvH. (164 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | EHY67433.1 | Hypothetical protein. (51 aa) |
| | EHY67430.1 | Acetyltransferase, GNAT family; Locus tag in AE006468 is STM4473; yjgM. (158 aa) |
| | argF-2 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa) |
| | vapC | Toxin-antitoxin system, toxin component, PIN family; Toxic component of a toxin-antitoxin (TA) system. A site- specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Its toxic effects are neutralized by expression of cognate antitoxin VapB; Belongs to the PINc/VapC protein family. (138 aa) |
| | fxsA | FxsA cytoplasmic membrane protein; Locus tag in AE006468 is STM4327; fxsA. (158 aa) |
| | tyrB | Aromatic-amino-acid transaminase TyrB; KEGG: ses:SARI_03430 1.5e-203 aromatic amino acid aminotransferase; K00832 aromatic-amino-acid transaminase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4248; tyrB. (397 aa) |
| | lysC | Aspartate kinase, monofunctional class; Locus tag in AE006468 is STM4220; lysC; Belongs to the aspartokinase family. (449 aa) |
| | EHY67160.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa) |
| | metAS | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (309 aa) |
| | argH | Argininosuccinate lyase; KEGG: spq:SPAB_05108 3.8e-239 argininosuccinate lyase; K01755 argininosuccinate lyase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM4123; argH. (457 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) |
| | argE | KEGG: set:SEN3915 1.6e-208 argE; acetylornithine deacetylase; K01438 acetylornithine deacetylase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM4120; argE. (383 aa) |
| | fsa | Fructose-6-phosphate aldolase; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily. (220 aa) |
| | metL | Homoserine dehydrogenase; KEGG: sty:STY3768 0. metL, metM; bifunctional aspartate kinase II/homoserine dehydrogenase II K12525; Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM4101; metL; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa) |
| | EHY67714.1 | O-succinylhomoserine (thiol)-lyase; KEGG: sew:SeSA_A4317 3.7e-200 metB; cystathionine gamma-synthase K01739; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4100; metB. (386 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | EHY67635.1 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (326 aa) |
| | EHY67610.1 | Thioesterase domain protein; KEGG: ecv:APECO1_2579 9.0e-167 yiiD; acetyltransferase; K00633 galactoside O-acetyltransferase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM4029; yiiD. (329 aa) |
| | glnA | KEGG: sec:SC3899 3.4e-254 glnA; glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4007; glnA. (469 aa) |
| | rdoA | Serine/threonine protein kinase RdoA; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (754 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa) |
| | ilvA | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) |
| | ilvD | KEGG: seh:SeHA_C4235 0. ilvD; dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3904; ilvD; Belongs to the IlvD/Edd family. (616 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa) |
| | ilvM | KEGG: sed:SeD_A4292 8.0e-40 ilvM; acetolactate synthase 2 regulatory subunit K11258; locus tag in AE006468 is STM3902; ilvM. (87 aa) |
| | EHY68204.1 | KEGG: ses:SARI_03751 1.0e-284 acetolactate synthase 2 catalytic subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3901; ilvG. (548 aa) |
| | asnA | Aspartate--ammonia ligase; KEGG: spq:SPAB_04821 5.4e-176 asparagine synthetase AsnA; K01914 aspartate--ammonia ligase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3877; asnA. (330 aa) |
| | ilvB | KEGG: sei:SPC_3877 5.4e-295 ilvB; acetolactate synthase large subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3796; ilvB. (562 aa) |
| | ilvN | KEGG: ses:SARI_03854 2.7e-46 acetolactate synthase 1 regulatory subunit; K01653 acetolactate synthase I/III small subunit; locus tag in AE006468 is STM3795; ilvN. (96 aa) |
