STRINGSTRING
AKB11781.1 AKB11781.1 AKB11782.1 AKB11782.1 AKB11783.1 AKB11783.1 AKB11784.1 AKB11784.1 ribL ribL AKB12084.1 AKB12084.1 mptE mptE AKB12745.1 AKB12745.1 AKB12746.1 AKB12746.1 AKB12747.1 AKB12747.1 AKB12748.1 AKB12748.1 AKB12842.1 AKB12842.1 AKB13198.1 AKB13198.1 AKB13199.1 AKB13199.1 AKB13200.1 AKB13200.1 AKB13201.1 AKB13201.1 AKB13202.1 AKB13202.1 AKB13203.1 AKB13203.1 AKB13204.1 AKB13204.1 htpX-2 htpX-2 AKB13496.1 AKB13496.1 AKB13497.1 AKB13497.1 AKB13518.1 AKB13518.1 AKB13576.1 AKB13576.1 AKB13577.1 AKB13577.1 mptD mptD purP purP ribK ribK ribB ribB AKB14050.1 AKB14050.1 AKB14051.1 AKB14051.1 queE queE AKB14053.1 AKB14053.1 queC queC AKB14106.1 AKB14106.1 AKB14181.1 AKB14181.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB11781.1Putative manganese-dependent inorganic pyrophosphatase. (186 aa)
AKB11782.1Serine--glyoxylate aminotransferase. (383 aa)
AKB11783.1Riboflavin synthase archaeal. (154 aa)
AKB11784.16,7-dimethyl-8-ribityllumazine synthase. (134 aa)
ribLFMN adenylyltransferase, type 3 archaeal; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (139 aa)
AKB12084.1Hypothetical protein. (491 aa)
mptE6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (213 aa)
AKB12745.1Phosphopantothenoylcysteine synthetase. (455 aa)
AKB12746.1Pantoate kinase, archaeal. (337 aa)
AKB12747.1Phosphopantothenate synthetase, archaeal. (253 aa)
AKB12748.1Metal-dependent phosphohydrolase. (227 aa)
AKB12842.1Dihydropteroate synthase; Alternative dihydrofolate reductase 2. (408 aa)
AKB13198.1Small primase-like proteins (Toprim domain); Belongs to the UPF0292 family. (146 aa)
AKB13199.1Hypothetical protein; Belongs to the UPF0235 family. (105 aa)
AKB13200.1Hypothetical protein. (39 aa)
AKB13201.1Pyrimidine deaminase archaeal predicted. (369 aa)
AKB13202.1Universal stress protein. (150 aa)
AKB13203.1Inosine-5'-monophosphate dehydrogenase. (284 aa)
AKB13204.15-amino-6-(5-phosphoribosylamino)uracil reductase. (239 aa)
htpX-2Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. (287 aa)
AKB13496.17,8 dihydropteroate synthase (methanopterin). (220 aa)
AKB13497.1Transcriptional repressor of nif and glnA operons. (322 aa)
AKB13518.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase. (223 aa)
AKB13576.1Sugar phosphate isomerase/epimerase. (257 aa)
AKB13577.1DUF54 conserved in archaea; Belongs to the UPF0201 family. (162 aa)
mptDDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). (122 aa)
purPPhosphoribosylaminoimidazolecarboxamide formyltransferase(alternate form); Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (356 aa)
ribKDNA-binding HTH domain in riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (225 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (246 aa)
AKB14050.1Nitrogenase FeMo-cofactor synthesis FeS core scaffold and assembly protein NifB. (323 aa)
AKB14051.1Queuosine biosynthesis QueD, PTPS-I. (116 aa)
queEQueuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (255 aa)
AKB14053.1Hypothetical protein. (202 aa)
queCQueuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (231 aa)
AKB14106.1Exopolyphosphatase-related protein. (335 aa)
AKB14181.15-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase. (387 aa)
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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