node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKB12709.1 | AKB13908.1 | MSTHT_0951 | MSTHT_2150 | Homoserine dehydrogenase. | Aspartate-semialdehyde dehydrogenase. | 0.989 |
AKB12709.1 | aroE | MSTHT_0951 | MSTHT_1783 | Homoserine dehydrogenase. | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.452 |
AKB12709.1 | dapB | MSTHT_0951 | MSTHT_1669 | Homoserine dehydrogenase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.683 |
AKB12709.1 | ilvC | MSTHT_0951 | MSTHT_2354 | Homoserine dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.552 |
AKB12709.1 | proA | MSTHT_0951 | MSTHT_1438 | Homoserine dehydrogenase. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.528 |
AKB13908.1 | AKB12709.1 | MSTHT_2150 | MSTHT_0951 | Aspartate-semialdehyde dehydrogenase. | Homoserine dehydrogenase. | 0.989 |
AKB13908.1 | aroE | MSTHT_2150 | MSTHT_1783 | Aspartate-semialdehyde dehydrogenase. | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.593 |
AKB13908.1 | dapB | MSTHT_2150 | MSTHT_1669 | Aspartate-semialdehyde dehydrogenase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.774 |
AKB13908.1 | gap | MSTHT_2150 | MSTHT_0429 | Aspartate-semialdehyde dehydrogenase. | NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. | 0.583 |
AKB13908.1 | ilvC | MSTHT_2150 | MSTHT_2354 | Aspartate-semialdehyde dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.588 |
AKB13908.1 | proA | MSTHT_2150 | MSTHT_1438 | Aspartate-semialdehyde dehydrogenase. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.410 |
aroE | AKB12709.1 | MSTHT_1783 | MSTHT_0951 | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Homoserine dehydrogenase. | 0.452 |
aroE | AKB13908.1 | MSTHT_1783 | MSTHT_2150 | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Aspartate-semialdehyde dehydrogenase. | 0.593 |
dapB | AKB12709.1 | MSTHT_1669 | MSTHT_0951 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Homoserine dehydrogenase. | 0.683 |
dapB | AKB13908.1 | MSTHT_1669 | MSTHT_2150 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Aspartate-semialdehyde dehydrogenase. | 0.774 |
dapB | proA | MSTHT_1669 | MSTHT_1438 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.482 |
gap | AKB13908.1 | MSTHT_0429 | MSTHT_2150 | NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. | Aspartate-semialdehyde dehydrogenase. | 0.583 |
ilvC | AKB12709.1 | MSTHT_2354 | MSTHT_0951 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Homoserine dehydrogenase. | 0.552 |
ilvC | AKB13908.1 | MSTHT_2354 | MSTHT_2150 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Aspartate-semialdehyde dehydrogenase. | 0.588 |
proA | AKB12709.1 | MSTHT_1438 | MSTHT_0951 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Homoserine dehydrogenase. | 0.528 |