STRINGSTRING
AKB11942.1 AKB11942.1 gap gap eno eno gpmA gpmA AKB12519.1 AKB12519.1 AKB12585.1 AKB12585.1 AKB12780.1 AKB12780.1 AKB12797.1 AKB12797.1 pgk pgk pfkC pfkC AKB12816.1 AKB12816.1 AKB12867.1 AKB12867.1 AKB12927.1 AKB12927.1 AKB13039.1 AKB13039.1 gpmI gpmI aroA-2 aroA-2 tpiA tpiA AKB13600.1 AKB13600.1 AKB13601.1 AKB13601.1 AKB13602.1 AKB13602.1 AKB13603.1 AKB13603.1 apgM apgM AKB13802.1 AKB13802.1 AKB13880.1 AKB13880.1 aroA-3 aroA-3 AKB14072.1 AKB14072.1 AKB14073.1 AKB14073.1 AKB14283.1 AKB14283.1 AKB14284.1 AKB14284.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB11942.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (803 aa)
gapNAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (335 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (238 aa)
AKB12519.1Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa)
AKB12585.1Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (561 aa)
AKB12780.1Acetyl-CoA synthetase (ADP-forming) alpha chain. (455 aa)
AKB12797.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (247 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa)
pfkCADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (490 aa)
AKB12816.1ADP-dependent glucokinase. (466 aa)
AKB12867.1Fructose-1,6-bisphosphatase, GlpX type. (385 aa)
AKB12927.1Glucose-6-phosphate isomerase. (242 aa)
AKB13039.1Glucose-6-phosphate isomerase. (246 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (515 aa)
aroA-22-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (265 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa)
AKB13600.1Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa)
AKB13601.1Pyruvate:ferredoxin oxidoreductase, alpha subunit. (402 aa)
AKB13602.1Pyruvate:ferredoxin oxidoreductase, delta subunit. (111 aa)
AKB13603.1Pyruvate:ferredoxin oxidoreductase, gamma subunit. (182 aa)
apgM2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (398 aa)
AKB13802.1Phosphomannomutase; Belongs to the phosphohexose mutase family. (420 aa)
AKB13880.1Pyruvate,phosphate dikinase. (883 aa)
aroA-32-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (286 aa)
AKB14072.1Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
AKB14073.1Fructose-bisphosphate aldolase/6-deoxy-5-ketofructose 1-phosphate synthase. (307 aa)
AKB14283.12-oxoglutarate oxidoreductase, beta subunit. (283 aa)
AKB14284.12-oxoglutarate oxidoreductase, alpha subunit. (579 aa)
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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