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AKB11785.1 AKB11785.1 ala ala AKB11915.1 AKB11915.1 AKB12117.1 AKB12117.1 AKB12140.1 AKB12140.1 carA carA carB carB argG argG AKB12440.1 AKB12440.1 purQ purQ AKB12595.1 AKB12595.1 AKB12618.1 AKB12618.1 argH argH AKB12781.1 AKB12781.1 purF purF AKB13302.1 AKB13302.1 AKB13320.1 AKB13320.1 pyrB pyrB pyrI pyrI AKB14013.1 AKB14013.1 purA purA AKB14118.1 AKB14118.1 AKB14275.1 AKB14275.1 glmS glmS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB11785.1Aspartate aminotransferase. (380 aa)
alaOrnithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (326 aa)
AKB11915.1Asparagine synthetase (glutamine-hydrolyzing). (488 aa)
AKB12117.1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (417 aa)
AKB12140.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (369 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1090 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (394 aa)
AKB12440.1Glutamine synthetase type I. (506 aa)
purQPhosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (232 aa)
AKB12595.1Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase. (370 aa)
AKB12618.1Succinate-semialdehyde dehydrogenase [NADP+]. (454 aa)
argHArgininosuccinate lyase. (491 aa)
AKB12781.1Glutamate dehydrogenase 2; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (377 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (483 aa)
AKB13302.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
AKB13320.1Glutamine synthetase type I. (452 aa)
pyrBAspartate carbamoyltransferase. (298 aa)
pyrIAspartate carbamoyltransferase regulatory chain (PyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
AKB14013.1Succinate-semialdehyde dehydrogenase [NADP+]. (411 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (424 aa)
AKB14118.1Glutamate synthase [NADPH] small chain. (469 aa)
AKB14275.1Succinate-semialdehyde dehydrogenase [NADP+]. (454 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (617 aa)
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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