STRINGSTRING
AKB11785.1 AKB11785.1 AKB11787.1 AKB11787.1 AKB11788.1 AKB11788.1 AKB11995.1 AKB11995.1 AKB12096.1 AKB12096.1 AKB12097.1 AKB12097.1 AKB12102.1 AKB12102.1 metXA metXA AKB12181.1 AKB12181.1 AKB12595.1 AKB12595.1 AKB12709.1 AKB12709.1 dadD dadD AKB12751.1 AKB12751.1 AKB13041.1 AKB13041.1 AKB13088.1 AKB13088.1 AKB13189.1 AKB13189.1 AKB13252.1 AKB13252.1 ilvE ilvE AKB13611.1 AKB13611.1 AKB13612.1 AKB13612.1 AKB13629.1 AKB13629.1 AKB13670.1 AKB13670.1 AKB13687.1 AKB13687.1 mat mat AKB13865.1 AKB13865.1 AKB13908.1 AKB13908.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB11785.1Aspartate aminotransferase. (380 aa)
AKB11787.1Inosine-5'-monophosphate dehydrogenase. (500 aa)
AKB11788.1Ferredoxin. (128 aa)
AKB11995.15'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. (258 aa)
AKB12096.1Serine acetyltransferase; PaaD-like protein (DUF59) involved in Fe-S cluster assembly. (323 aa)
AKB12097.1Cysteine synthase. (308 aa)
AKB12102.1O-succinylhomoserine sulfhydrylase. (447 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (519 aa)
AKB12181.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (347 aa)
AKB12595.1Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase. (370 aa)
AKB12709.1Homoserine dehydrogenase. (332 aa)
dadDS-adenosylhomocysteine deaminase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon th [...] (432 aa)
AKB12751.1Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (411 aa)
AKB13041.1Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (307 aa)
AKB13088.1Archaeal S-adenosylmethionine synthetase. (410 aa)
AKB13189.1Serine O-acetyltransferase. (209 aa)
AKB13252.1Serine O-acetyltransferase. (141 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa)
AKB13611.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (348 aa)
AKB13612.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (344 aa)
AKB13629.1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (369 aa)
AKB13670.1Aspartokinase; Belongs to the aspartokinase family. (472 aa)
AKB13687.1Ribosomal RNA adenine dimethylase. (238 aa)
matArchaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (398 aa)
AKB13865.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (523 aa)
AKB13908.1Aspartate-semialdehyde dehydrogenase. (342 aa)
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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