STRINGSTRING
AKB11896.1 AKB11896.1 mobA mobA AKB11928.1 AKB11928.1 mptE mptE AKB12513.1 AKB12513.1 AKB12842.1 AKB12842.1 AKB13210.1 AKB13210.1 AKB13273.1 AKB13273.1 mptA mptA AKB13496.1 AKB13496.1 AKB13533.1 AKB13533.1 moaA moaA mptD mptD AKB13713.1 AKB13713.1 AKB13926.1 AKB13926.1 AKB14010.1 AKB14010.1 AKB14051.1 AKB14051.1 queE queE queC queC moaC moaC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB11896.1Tetrahydromethanopterin:alpha-L-glutamate ligase. (328 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (225 aa)
AKB11928.1Molybdopterin-guanine dinucleotide biosynthesis protein MobB. (281 aa)
mptE6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (213 aa)
AKB12513.1Molybdenum cofactor biosynthesis protein MoaA. (264 aa)
AKB12842.1Dihydropteroate synthase; Alternative dihydrofolate reductase 2. (408 aa)
AKB13210.1Molybdopterin biosynthesis MoeA protein. (397 aa)
AKB13273.1Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (320 aa)
mptAGTP cyclohydrolase I type 2; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (319 aa)
AKB13496.17,8 dihydropteroate synthase (methanopterin). (220 aa)
AKB13533.1Molybdopterin biosynthesis protein MoeA; Periplasmic molybdate-binding domain. (642 aa)
moaAMolybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (332 aa)
mptDDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). (122 aa)
AKB13713.1Molybdenum cofactor biosynthesis protein MoaB. (179 aa)
AKB13926.1Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (321 aa)
AKB14010.1Indolepyruvate oxidoreductase subunit IorA. (223 aa)
AKB14051.1Queuosine biosynthesis QueD, PTPS-I. (116 aa)
queEQueuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (255 aa)
queCQueuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (231 aa)
moaCMolybdenum cofactor biosynthesis enzyme; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (141 aa)
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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