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ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (553 aa) | ||||
AKB11785.1 | Aspartate aminotransferase. (380 aa) | ||||
AKB12190.1 | Coenzyme B synthesis from 2-oxoglutarate: steps 1, 6, and 10; Belongs to the alpha-IPM synthase/homocitrate synthase family. (405 aa) | ||||
leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (431 aa) | ||||
AKB12595.1 | Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase. (370 aa) | ||||
AKB12619.1 | Acetolactate synthase; Belongs to the TPP enzyme family. (544 aa) | ||||
argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (337 aa) | ||||
argJ | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (395 aa) | ||||
AKB13345.1 | 2-isopropylmalate synthase. (442 aa) | ||||
AKB13346.1 | 3-isopropylmalate dehydrogenase. (342 aa) | ||||
AKB13375.1 | GCN5-related N-acetyltransferase. (151 aa) | ||||
ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa) | ||||
argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa) | ||||
AKB13551.1 | 2-isopropylmalate synthase. (430 aa) | ||||
argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa) | ||||
AKB13670.1 | Aspartokinase; Belongs to the aspartokinase family. (472 aa) | ||||
leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (167 aa) | ||||
AKB13795.1 | Aconitate hydratase. (934 aa) | ||||
AKB13796.1 | Citrate synthase (si). (355 aa) | ||||
AKB13804.1 | N-acetylglutamate synthase. (146 aa) | ||||
AKB13908.1 | Aspartate-semialdehyde dehydrogenase. (342 aa) | ||||
cimA | (R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. (483 aa) | ||||
AKB14110.1 | Acetolactate synthase large subunit. (587 aa) | ||||
AKB14111.1 | Acetolactate synthase small subunit. (161 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa) | ||||
hacB | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] (166 aa) | ||||
AKB14136.1 | Coenzyme B synthesis from 2-oxoglutarate: steps 5, 9, and 13. (330 aa) | ||||
leuC-2 | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (413 aa) |