STRINGSTRING
iscS iscS AKB11928.1 AKB11928.1 iscS-2 iscS-2 AKB12513.1 AKB12513.1 AKB12566.1 AKB12566.1 AKB12683.1 AKB12683.1 AKB12684.1 AKB12684.1 thiI thiI AKB13050.1 AKB13050.1 AKB13052.1 AKB13052.1 AKB13211.1 AKB13211.1 moaA moaA AKB13713.1 AKB13713.1 AKB13789.1 AKB13789.1 moaC moaC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (396 aa)
AKB11928.1Molybdopterin-guanine dinucleotide biosynthesis protein MobB. (281 aa)
iscS-2Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa)
AKB12513.1Molybdenum cofactor biosynthesis protein MoaA. (264 aa)
AKB12566.1Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (243 aa)
AKB12683.1Uncharacterized protein involved in the oxidation of intracellular sulfur. (114 aa)
AKB12684.1Hypothetical protein. (126 aa)
thiItRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (506 aa)
AKB13050.1Hypothetical protein. (75 aa)
AKB13052.1Homocysteine desulfhydrase. (365 aa)
AKB13211.1Molybdopterin converting factor small subunit. (75 aa)
moaAMolybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (332 aa)
AKB13713.1Molybdenum cofactor biosynthesis protein MoaB. (179 aa)
AKB13789.1Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (247 aa)
moaCMolybdenum cofactor biosynthesis enzyme; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (141 aa)
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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