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fadI fadI EFK37479.1 EFK37479.1 accD accD mce mce acnB acnB mutB_2 mutB_2 yfeX yfeX scpA_1 scpA_1 accA accA accC accC accB accB sucC sucC EFK32962.1 EFK32962.1 sucD sucD EFK33356.1 EFK33356.1 pdhB pdhB lpdA lpdA EFK34073.1 EFK34073.1 yhdH yhdH yhfP yhfP lpdA-2 lpdA-2 EFK34415.1 EFK34415.1 mutB_1 mutB_1 thlA_2 thlA_2 fdhA fdhA thlA_1 thlA_1 acsA_2 acsA_2 acsA acsA lpdA-3 lpdA-3 yqhD yqhD bfmBAB_2 bfmBAB_2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
fadIacetyl-CoA C-acetyltransferase; COG: COG0183; Pfam: PF00108,PF02803; InterPro: IPR002155; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
EFK37479.1LD-carboxypeptidase; COG: COG1619; Pfam: PF02016; InterPro: IPR003507. (309 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (284 aa)
mcemethylmalonyl-CoA epimerase; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. (132 aa)
acnBAconitate hydratase 2 domain protein; COG: COG1049; Pfam: PF06434,PF00330; InterPro: IPR015937. (927 aa)
mutB_2B12 binding domain protein; COG: COG1884; Pfam: PF01642,PF02310; InterPro: IPR006098. (705 aa)
yfeXDyp-type peroxidase family protein; COG: COG2837; Pfam: PF04261; InterPro: IPR006314. (312 aa)
scpA_1B12 binding domain protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1115 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (468 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa)
sucCsuccinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
EFK32962.1Hypothetical protein. (132 aa)
sucDsuccinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
EFK33356.1Hypothetical protein; COG: COG3564; Pfam: PF05610; InterPro: IPR008497; 5.1.3.2. (127 aa)
pdhBTransketolase, C-terminal domain protein; COG: COG0022; Pfam: PF00676,PF02779,PF02780; InterPro: IPR015941. (810 aa)
lpdADihydrolipoyl dehydrogenase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006258. (462 aa)
EFK34073.1Dyp-type peroxidase family protein; InterPro: IPR006314. (452 aa)
yhdHQuinone oxidoreductase, YhdH/YhfP family; COG: COG0604; Pfam: PF08240; InterPro: IPR014188. (188 aa)
yhfPHypothetical protein; COG: COG0604; InterPro: IPR016040. (128 aa)
lpdA-2Dihydrolipoyl dehydrogenase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006258. (467 aa)
EFK34415.1Hypothetical protein; Pfam: PF02222. (404 aa)
mutB_1methylmalonyl-CoA mutase domain protein; COG: COG1884; Pfam: PF01642; InterPro: IPR014348. (387 aa)
thlA_2acetyl-CoA C-acetyltransferase; COG: COG0183; Pfam: PF00108,PF02803; InterPro: IPR002155; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
fdhAGroES-like protein; COG: COG1063; Pfam: PF08240,PF00107; InterPro: IPR002085. (388 aa)
thlA_1acetyl-CoA C-acetyltransferase; COG: COG0183; Pfam: PF00108,PF02803; InterPro: IPR002155; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
acsA_2AMP-binding enzyme; COG: COG0365; Pfam: PF00501; InterPro: IPR000873. (628 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
lpdA-3Dihydrolipoyl dehydrogenase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006258. (466 aa)
yqhDAlcohol dehydrogenase, iron-dependent; COG: COG1979; Pfam: PF00465; InterPro: IPR001670. (387 aa)
bfmBAB_2Transketolase, pyridine binding domain protein; COG: COG0022; Pfam: PF00676,PF02779,PF02780; InterPro: IPR001017. (690 aa)
Your Current Organism:
Chryseobacterium gleum
NCBI taxonomy Id: 525257
Other names: C. gleum ATCC 35910, Chryseobacterium gleum ATCC 35910, Chryseobacterium gleum CCUG 14555, Chryseobacterium gleum str. ATCC 35910, Chryseobacterium gleum strain ATCC 35910
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