STRINGSTRING
EFK55873.1 EFK55873.1 EFK57839.1 EFK57839.1 yajC yajC EFK58577.1 EFK58577.1 EFK57830.1 EFK57830.1 secD secD EFK57707.1 EFK57707.1 ftsY ftsY EFK59794.1 EFK59794.1 EFK57536.1 EFK57536.1 gspF gspF yidC yidC tatA-2 tatA-2 secE secE EFK57403.1 EFK57403.1 tolC tolC EFK57444.1 EFK57444.1 EFK58740.1 EFK58740.1 clpB clpB EFK58138.1 EFK58138.1 gspD gspD gspE gspE gspG gspG ffh ffh tatC tatC tatA tatA secY secY secG secG EFK59713.1 EFK59713.1 EFK59790.1 EFK59790.1 secA secA EFK56958.1 EFK56958.1 EFK56956.1 EFK56956.1 EFK56835.1 EFK56835.1 EFK56696.1 EFK56696.1 EFK56300.1 EFK56300.1 EFK55946.1 EFK55946.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFK55873.1Outer membrane efflux protein; Pfam: PF02321. (456 aa)
EFK57839.1Outer membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (434 aa)
yajCPreprotein translocase, YajC subunit; COG: COG1862; Pfam: PF02699; InterPro: IPR003849. (107 aa)
EFK58577.1Outer membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (452 aa)
EFK57830.1Septum formation initiator; Pfam: PF04977. (100 aa)
secDExport membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (993 aa)
EFK57707.1ATPase family associated with various cellular activities (AAA); COG: COG0542; Pfam: PF02861,PF00004,PF02151,PF07724; InterPro: IPR003593; Belongs to the ClpA/ClpB family. (849 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (324 aa)
EFK59794.1S23 ribosomal protein; Pfam: PF05635; InterPro: IPR008815. (117 aa)
EFK57536.1TraG family protein. (667 aa)
gspFBacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. (384 aa)
yidCMembrane protein insertase, YidC/Oxa1 family domain protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (607 aa)
tatA-2Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (69 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (64 aa)
EFK57403.1Outer membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (446 aa)
tolCOuter membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (433 aa)
EFK57444.1Hypothetical protein. (460 aa)
EFK58740.1Outer membrane efflux protein; Pfam: PF02321. (479 aa)
clpBATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (868 aa)
EFK58138.1Outer membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (445 aa)
gspDSecretin and TonB N terminus short domain protein; Pfam: PF07660,PF00263; InterPro: IPR004846; Belongs to the bacterial secretin family. (624 aa)
gspEType II/IV secretion system protein; COG: COG2804; Pfam: PF00437; InterPro: IPR001482. (484 aa)
gspGPrepilin-type cleavage/methylation N-terminal domain protein; Pfam: PF07963. (138 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (445 aa)
tatCTwin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (292 aa)
tatATwin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (167 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (446 aa)
secGPreprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (123 aa)
EFK59713.1Outer membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (438 aa)
EFK59790.1S23 ribosomal protein; Pfam: PF05635; InterPro: IPR008815. (91 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (1099 aa)
EFK56958.1Hypothetical protein. (427 aa)
EFK56956.1TraG family protein. (666 aa)
EFK56835.1Outer membrane efflux protein; Pfam: PF02321. (438 aa)
EFK56696.1Hypothetical protein. (461 aa)
EFK56300.1Outer membrane efflux protein; Pfam: PF02321; InterPro: IPR003423. (458 aa)
EFK55946.1Hypothetical protein; COG: COG3012; Pfam: PF02810. (128 aa)
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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