STRINGSTRING
Sdel_0039 Sdel_0039 Sdel_0048 Sdel_0048 Sdel_0312 Sdel_0312 Sdel_0325 Sdel_0325 Sdel_0394 Sdel_0394 Sdel_0395 Sdel_0395 Sdel_0396 Sdel_0396 Sdel_0497 Sdel_0497 Sdel_0529 Sdel_0529 Sdel_0530 Sdel_0530 accD accD Sdel_0567 Sdel_0567 Sdel_0603 Sdel_0603 Sdel_0604 Sdel_0604 Sdel_0605 Sdel_0605 pckA pckA Sdel_0805 Sdel_0805 Sdel_0806 Sdel_0806 Sdel_0807 Sdel_0807 Sdel_0808 Sdel_0808 Sdel_0813 Sdel_0813 Sdel_0970 Sdel_0970 Sdel_0972 Sdel_0972 ackA ackA Sdel_1045 Sdel_1045 Sdel_1047 Sdel_1047 Sdel_1081 Sdel_1081 Sdel_1082 Sdel_1082 Sdel_1083 Sdel_1083 Sdel_1084 Sdel_1084 sucD sucD sucC sucC mdh mdh Sdel_1089 Sdel_1089 Sdel_1184 Sdel_1184 Sdel_1200 Sdel_1200 Sdel_1275 Sdel_1275 Sdel_1276 Sdel_1276 Sdel_1292 Sdel_1292 acsA acsA Sdel_1661 Sdel_1661 glmS glmS accA accA Sdel_1847 Sdel_1847 Sdel_1898 Sdel_1898 Sdel_2072 Sdel_2072 Sdel_2073 Sdel_2073 Sdel_2074 Sdel_2074 Sdel_2189 Sdel_2189 Sdel_2195 Sdel_2195 Sdel_2198 Sdel_2198 Sdel_2199 Sdel_2199 Sdel_2232 Sdel_2232
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Sdel_0039PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: tdn:Suden_1902 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (694 aa)
Sdel_0048PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: abu:Abu_1765 putative nitrilase/cyanide hydratase. (246 aa)
Sdel_0312PFAM: Aldehyde Dehydrogenase; KEGG: abu:Abu_0378 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa)
Sdel_0325PFAM: Lactate/malate dehydrogenase; KEGG: vpa:VPA0147 lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (309 aa)
Sdel_0394PFAM: Fumarate reductase respiratory complex; KEGG: abu:Abu_0301 fumarate reductase cytochrome b- 556 subunit. (260 aa)
Sdel_0395KEGG: ccv:CCV52592_2205 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (661 aa)
Sdel_0396TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_0424 fumarate reductase iron- sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (240 aa)
Sdel_0497Malate dehydrogenase (acceptor); PFAM: FAD dependent oxidoreductase; Malate:quinone- oxidoreductase; KEGG: sun:SUN_0432 malate:quinone oxidoreductase. (446 aa)
Sdel_0529PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: nis:NIS_1201 glutamate synthase (NADPH), large chain. (1474 aa)
Sdel_0530TIGRFAM: glutamate synthase, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tdn:Suden_1175 glutamate synthase subunit beta. (461 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
Sdel_0567PFAM: iron-containing alcohol dehydrogenase; KEGG: gur:Gura_3532 iron-containing alcohol dehydrogenase. (383 aa)
Sdel_0603PFAM: sodium pump decarboxylase gamma subunit; KEGG: sun:SUN_1434 Na+-transporting oxaloacetate decarboxylase, gamma subunit. (81 aa)
Sdel_0604PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. (601 aa)
Sdel_0605Sodium ion-translocating decarboxylase, beta subunit; KEGG: tdn:Suden_1258 pyruvate carboxylase/oxaloacetate decarboxylase biotin carboxyl carrier subunit alpha; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl- CoA/oxaloacetate decarboxylase beta subunit. (436 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (525 aa)
Sdel_0805PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: tdn:Suden_0820 formate dehydrogenase alpha subunit. (186 aa)
Sdel_0806PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase; KEGG: cco:CCC13826_0208 fumarate hydratase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (749 aa)
Sdel_0807PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1308 formate dehydrogenase subunit B. (199 aa)
Sdel_0808TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: dps:DP2988 formate dehydrogenase, gamma subunit. (299 aa)
Sdel_0813PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: ppd:Ppro_2088 formylmethanofuran dehydrogenase, subunit E region. (175 aa)
Sdel_0970TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; KEGG: nis:NIS_0828 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (853 aa)
Sdel_0972Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
Sdel_1045Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (702 aa)
Sdel_1047PFAM: acylphosphatase; KEGG: nam:NAMH_0944 acylphosphatase. (89 aa)
Sdel_1081PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: cha:CHAB381_1142 2-oxoglutarate-acceptor oxidoreductase subunit OorC. (185 aa)
Sdel_1082PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cff:CFF8240_0907 2-oxoglutarate-acceptor oxidoreductase subunit OorB. (277 aa)
Sdel_1083PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cla:Cla_0816 2-oxoglutarate:acceptor oxidoreductase, OorA subunit. (377 aa)
Sdel_1084PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sun:SUN_0578 2-oxoglutarate-acceptor oxidoreductase subunit OorD. (105 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)
Sdel_1089KEGG: son:SO_2629 isocitrate dehydrogenase, NADP- dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (745 aa)
Sdel_1184Heterodisulfide reductase subunit B-like protein; KEGG: sun:SUN_1202 succinate dehydrogenase/fumarate reductase, subunit C. (281 aa)
Sdel_1200PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: nam:NAMH_1054 glutamate synthase [NADPH] small chain. (473 aa)
Sdel_1275KEGG: sun:SUN_0573 fumarate/tartrate hydratase, alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (283 aa)
Sdel_1276TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: nam:NAMH_1232 C-terminal fumarate hydratase, class I. (187 aa)
Sdel_1292PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pca:Pcar_2295 putative oxidoreductase. (398 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
Sdel_1661TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: cff:CFF8240_1054 glutamine synthetase, type I. (476 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (603 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (312 aa)
Sdel_1847PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: abu:Abu_0605 acetyl CoA carboxylase, biotin carboxylase subunit. (481 aa)
Sdel_1898TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase. (1187 aa)
Sdel_2072TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: cjd:JJD26997_1861 formate dehydrogenase, cytochrome b subunit. (299 aa)
Sdel_2073PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_0209 cytoplasmic membrane protein. (210 aa)
Sdel_2074PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: dps:DP2986 formate dehydrogenase, chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (749 aa)
Sdel_2189Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sun:SUN_1928 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa)
Sdel_2195Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ccv:CCV52592_0547 malic enzyme NAD binding subunit. (424 aa)
Sdel_2198acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (443 aa)
Sdel_2199acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa)
Sdel_2232KEGG: cco:CCC13826_2287 citrate (Si)-synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (428 aa)
Your Current Organism:
Sulfurospirillum deleyianum
NCBI taxonomy Id: 525898
Other names: S. deleyianum DSM 6946, Sulfurospirillum deleyianum DSM 6946, Sulfurospirillum deleyianum str. DSM 6946, Sulfurospirillum deleyianum strain DSM 6946
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