STRINGSTRING
Sdel_1262 Sdel_1262 Sdel_0137 Sdel_0137 Sdel_2287 Sdel_2287 Sdel_2155 Sdel_2155 Sdel_2143 Sdel_2143 Sdel_2083 Sdel_2083 uppP uppP Sdel_1994 Sdel_1994 Sdel_1910 Sdel_1910 Sdel_1297 Sdel_1297 Sdel_1310 Sdel_1310 rppH rppH Sdel_1400 Sdel_1400 htpG htpG Sdel_1410 Sdel_1410 ftsZ ftsZ Sdel_1435 Sdel_1435 Sdel_1595 Sdel_1595 uvrB uvrB Sdel_1626 Sdel_1626 Sdel_1633 Sdel_1633 Sdel_1650 Sdel_1650 Sdel_1665 Sdel_1665 Sdel_1706 Sdel_1706 Sdel_1739 Sdel_1739 ftsH ftsH Sdel_1819 Sdel_1819 Sdel_1841 Sdel_1841 Sdel_1880 Sdel_1880 hisI hisI clpX clpX Sdel_0232 Sdel_0232 infB infB Sdel_0278 Sdel_0278 Sdel_0293 Sdel_0293 lepA lepA tuf tuf fusA fusA Sdel_0397 Sdel_0397 ruvB ruvB mutS2 mutS2 obg obg Sdel_0554 Sdel_0554 guaA guaA ychF ychF Sdel_0767 Sdel_0767 Sdel_0769 Sdel_0769 Sdel_0801 Sdel_0801 lon lon Sdel_0868 Sdel_0868 ftsY ftsY Sdel_0956 Sdel_0956 Sdel_1031 Sdel_1031 era era ruvA ruvA Sdel_1098 Sdel_1098
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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Sdel_1262PFAM: AAA ATPase central domain protein; peptidase M41; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: ccv:CCV52592_1068 putative cell division protease FtsH-like protein; Belongs to the AAA ATPase family. (553 aa)
Sdel_0137PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: nis:NIS_0287 AAA family ATPase. (577 aa)
Sdel_2287TIGRFAM: GTP-binding protein TypA; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: ccv:CCV52592_2046 GTP-binding protein TypA/BipA. (599 aa)
Sdel_2155Flagellar protein export ATPase FliI; KEGG: ccv:CCV52592_1495 flagellum-specific ATP synthase; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase. (434 aa)
Sdel_2143Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
Sdel_2083TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: nam:NAMH_1325 selenocysteine-specific translation elongation factor. (611 aa)
uppPUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (255 aa)
Sdel_1994PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: hhe:HH1306 hypothetical protein. (173 aa)
Sdel_1910PFAM: UvrD/REP helicase; KEGG: tdn:Suden_0090 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (907 aa)
Sdel_1297PFAM: Ppx/GppA phosphatase; KEGG: sun:SUN_1826 Ppx/GppA family phosphatase. (302 aa)
Sdel_1310KEGG: cco:CCC13826_0148 hypothetical protein. (783 aa)
rppHNUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (156 aa)
Sdel_1400PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: nis:NIS_0876 ATP-dependent Clp protease, ATP- binding subunit ClpB; Belongs to the ClpA/ClpB family. (856 aa)
htpGHeat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity. (623 aa)
Sdel_1410PFAM: UvrD/REP helicase; KEGG: ccv:CCV52592_1083 acyl carrier protein. (676 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (371 aa)
Sdel_1435PFAM: protein of unknown function DUF59; KEGG: nis:NIS_1811 hypothetical protein. (99 aa)
Sdel_1595Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (476 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa)
Sdel_1626KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP- binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. (732 aa)
Sdel_1633PFAM: UvrD/REP helicase; KEGG: nis:NIS_1473 ATP-dependent DNA helicase UvrD. (681 aa)
Sdel_1650KEGG: cco:CCC13826_1434 signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase. (446 aa)
Sdel_1665TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: nis:NIS_1525 Maf-like protein; Belongs to the Maf family. (184 aa)
Sdel_1706ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (375 aa)
Sdel_1739TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: ppd:Ppro_3226 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (900 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (643 aa)
Sdel_1819TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sun:SUN_1930 heavy-metal transporting P-type ATPase. (806 aa)
Sdel_1841PFAM: AAA ATPase central domain protein; peptidase M41; SMART: AAA ATPase; KEGG: nis:NIS_1070 hypothetical protein. (806 aa)
Sdel_1880PFAM: dUTPase; KEGG: cco:CCC13826_2153 dUTPase. (232 aa)
hisITIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: nis:NIS_1544 histidine biosynthesis bifunctional protein HisI; In the N-terminal section; belongs to the PRA-CH family. (227 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (412 aa)
Sdel_0232PFAM: Ppx/GppA phosphatase; KEGG: nis:NIS_0408 guanosine pentaphosphate phosphohydrolase. (488 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (888 aa)
Sdel_0278Inorganic diphosphatase; PFAM: DHHA2 domain protein; phosphoesterase RecJ domain protein; KEGG: sun:SUN_1298 putative manganese-dependent inorganic pyrophosphatase. (305 aa)
Sdel_0293KEGG: cco:CCC13826_0367 flagellar biosynthesis regulator FlhF; TIGRFAM: flagellar biosynthetic protein FlhF; PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase. (423 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (597 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (692 aa)
Sdel_0397PFAM: Dynamin family protein; KEGG: abu:Abu_0298 ATP/GTP-binding protein. (789 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (340 aa)
mutS2Smr protein/MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (733 aa)
obgGTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (368 aa)
Sdel_0554Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (938 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (511 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
Sdel_0767Hypothetical protein. (185 aa)
Sdel_0769Hypothetical protein. (105 aa)
Sdel_0801TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: wsu:WS1121 heavy metal-transporting ATPase. (682 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (807 aa)
Sdel_0868TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: nam:NAMH_1151 septum site-determining protein MinD. (269 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (294 aa)
Sdel_0956KEGG: intracellular protein transport protein USO1. (1234 aa)
Sdel_1031Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (441 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (296 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (186 aa)
Sdel_1098TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cco:CCC13826_1096 hydrogenase accessory protein HypB. (278 aa)
Your Current Organism:
Sulfurospirillum deleyianum
NCBI taxonomy Id: 525898
Other names: S. deleyianum DSM 6946, Sulfurospirillum deleyianum DSM 6946, Sulfurospirillum deleyianum str. DSM 6946, Sulfurospirillum deleyianum strain DSM 6946
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