STRINGSTRING
acpP acpP Sdel_1837 Sdel_1837 gpmI gpmI Sdel_0057 Sdel_0057 fabZ fabZ Sdel_2198 Sdel_2198 Sdel_2195 Sdel_2195 Sdel_2124 Sdel_2124 Sdel_2123 Sdel_2123 Sdel_2122 Sdel_2122 Sdel_2118 Sdel_2118 Sdel_2111 Sdel_2111 Sdel_2110 Sdel_2110 Sdel_2109 Sdel_2109 Sdel_2105 Sdel_2105 Sdel_1847 Sdel_1847 dxr dxr eno eno bioB bioB Sdel_2199 Sdel_2199 plsX plsX Sdel_2101 Sdel_2101 Sdel_2100 Sdel_2100 Sdel_2097 Sdel_2097 panD panD Sdel_1466 Sdel_1466 Sdel_1932 Sdel_1932 Sdel_1457 Sdel_1457 Sdel_1441 Sdel_1441 bioA bioA Sdel_1339 Sdel_1339 Sdel_1184 Sdel_1184 Sdel_1124 Sdel_1124 pgi pgi Sdel_1092 Sdel_1092 Sdel_1089 Sdel_1089 Sdel_1059 Sdel_1059 Sdel_0972 Sdel_0972 acpS acpS Sdel_0753 Sdel_0753 ispH ispH aroE aroE accD accD Sdel_0525 Sdel_0525 Sdel_0501 Sdel_0501 panC panC Sdel_0424 Sdel_0424 Sdel_0423 Sdel_0423 pgk pgk panB panB fabH fabH Sdel_1875 Sdel_1875 Sdel_1864 Sdel_1864 Sdel_1863 Sdel_1863 Sdel_1469 Sdel_1469 acsA acsA Sdel_1592 Sdel_1592 ispG ispG bioD bioD ispDF ispDF accA accA Sdel_1835 Sdel_1835
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa)
Sdel_18373-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (496 aa)
Sdel_0057PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: slo:Shew_1535 fumarylacetoacetate (FAA) hydrolase. (204 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (149 aa)
Sdel_2198acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (443 aa)
Sdel_2195Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ccv:CCV52592_0547 malic enzyme NAD binding subunit. (424 aa)
Sdel_2124KEGG: pca:Pcar_2651 acyl-carrier protein. (83 aa)
Sdel_2123PFAM: Beta-ketoacyl synthase; KEGG: afr:AFE_0796 3-oxoacyl-(acyl carrier protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (371 aa)
Sdel_2122KEGG: swp:swp_0307 hypothetical protein. (213 aa)
Sdel_2118PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu2164 3-oxoacyl-(acyl carrier protein) synthase III. (380 aa)
Sdel_2111KEGG: aap:NT05HA_1744 hypothetical protein. (244 aa)
Sdel_2110PFAM: Beta-ketoacyl synthase; KEGG: dar:Daro_2374 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (385 aa)
Sdel_2109KEGG: dar:Daro_2373 acyl carrier protein. (89 aa)
Sdel_2105KEGG: fph:Fphi_1084 aconitate hydratase. (393 aa)
Sdel_1847PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: abu:Abu_0605 acetyl CoA carboxylase, biotin carboxylase subunit. (481 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (355 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (283 aa)
Sdel_2199acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (330 aa)
Sdel_2101PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: dar:Daro_4188 3-ketoacyl-(acyl-carrier- protein) reductase. (229 aa)
Sdel_2100PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sbm:Shew185_0334 histidine ammonia-lyase. (506 aa)
Sdel_2097PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: ttu:TERTU_3274 FabA domain protein. (108 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (121 aa)
Sdel_1466PFAM: Phosphoglycerate mutase; KEGG: dat:HRM2_06990 putative molybdopterine- guanine dinucleotide biosynthesis protein MobA. (198 aa)
Sdel_1932TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: dal:Dalk_1233 HAD-superfamily hydrolase, subfamily IA, variant 1. (218 aa)
Sdel_1457PFAM: AMP-dependent synthetase and ligase; KEGG: dps:DP1333 long-chain-fatty-acid--CoA ligase. (629 aa)
Sdel_1441PFAM: thioesterase superfamily protein; KEGG: wsu:WS1541 acyl-CoA hydrolase. (161 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoateaminotr ansferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (434 aa)
Sdel_1339Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
Sdel_1184Heterodisulfide reductase subunit B-like protein; KEGG: sun:SUN_1202 succinate dehydrogenase/fumarate reductase, subunit C. (281 aa)
Sdel_1124Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: sun:SUN_1935 glucose-6-phosphate isomerase; Belongs to the GPI family. (422 aa)
Sdel_1092TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: nis:NIS_1852 HAD-superfamily hydrolase. (212 aa)
Sdel_1089KEGG: son:SO_2629 isocitrate dehydrogenase, NADP- dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (745 aa)
Sdel_1059PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cco:CCC13826_0121 7-alpha-hydroxysteroid dehydrogenase. (255 aa)
Sdel_0972Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa)
acpSHolo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (124 aa)
Sdel_0753PFAM: protein of unknown function DUF1121; KEGG: abu:Abu_1579 hypothetical protein. (198 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (277 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (263 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
Sdel_0525TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: abu:Abu_1586 malonyl coenzyme A-(acyl carrier protein) transacylase. (307 aa)
Sdel_0501Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (481 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (273 aa)
Sdel_0424PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cco:CCC13826_0513 enoyl-(acyl carrier protein) reductase. (273 aa)
Sdel_0423PFAM: triosephosphate isomerase; KEGG: abu:Abu_2134 triosephosphate isomerase. (237 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: cjr:CJE1589 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
panB3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (278 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (330 aa)
Sdel_1875PFAM: thioesterase superfamily protein; KEGG: cla:Cla_1269 conserved hypothetical protein, putative acyl-coA thioester hydrolase. (139 aa)
Sdel_1864PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: wsu:WS1840 hydrogenase 4 membrane subunit. (215 aa)
Sdel_1863PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: wsu:WS1841 hydrogenase-4 component C. (308 aa)
Sdel_1469KEGG: sfu:Sfum_1315 hypothetical protein. (431 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
Sdel_1592D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: cha:CHAB381_1615 glycolate oxidase, subunit GlcD. (459 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (354 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (224 aa)
ispDF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (374 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (312 aa)
Sdel_18353-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (402 aa)
Your Current Organism:
Sulfurospirillum deleyianum
NCBI taxonomy Id: 525898
Other names: S. deleyianum DSM 6946, Sulfurospirillum deleyianum DSM 6946, Sulfurospirillum deleyianum str. DSM 6946, Sulfurospirillum deleyianum strain DSM 6946
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