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| | Sdel_1098 | TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cco:CCC13826_1096 hydrogenase accessory protein HypB. (278 aa) |
| | Sdel_0020 | TIGRFAM: nickel ABC transporter, periplasmic nickel- binding protein; PFAM: extracellular solute-binding protein family 5; KEGG: wsu:WS0984 putative NikA protein. (539 aa) |
| | Sdel_0030 | PFAM: MOSC domain containing protein; KEGG: tdn:Suden_0548 MOSC. (230 aa) |
| | Sdel_0034 | PFAM: AMMECR1 domain protein; KEGG: nis:NIS_1597 hypothetical protein. (180 aa) |
| | rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (664 aa) |
| | nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (280 aa) |
| | nuoB | NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (169 aa) |
| | nuoI | NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (204 aa) |
| | clpX | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (412 aa) |
| | Sdel_0282 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (328 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (214 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1507 aa) |
| | Sdel_0387 | KEGG: xom:XOO_4008 hypothetical protein. (242 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (918 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (370 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) |
| | Sdel_0534 | PFAM: zinc finger DksA/TraR C4-type; KEGG: cco:CCC13826_0939 TraR/DksA family transcriptional regulator. (119 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (622 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (376 aa) |
| | ybeY | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (140 aa) |
| | Sdel_0703 | Conserved hypothetical protein; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process; Belongs to the multiheme cytochrome c family. (690 aa) |
| | napA | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (929 aa) |
| | Sdel_0810 | PFAM: regulatory protein LysR; TOBE domain protein; KEGG: abu:Abu_0013 molybdenum-binding protein. (260 aa) |
| | Sdel_0813 | PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: ppd:Ppro_2088 formylmethanofuran dehydrogenase, subunit E region. (175 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (731 aa) |
| | htpX | PFAM: peptidase M48 Ste24p; KEGG: cha:CHAB381_0401 M48 family peptidase; Belongs to the peptidase M48B family. (283 aa) |
| | pepA | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (483 aa) |
| | mqnC | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (350 aa) |
| | ribB-2 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. (340 aa) |
| | Sdel_1021 | PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: cco:CCC13826_0703 adenylosuccinate lyase. (276 aa) |
| | Sdel_1037 | SMART: AAA ATPase; KEGG: cha:CHAB381_1055 hypothetical protein. (269 aa) |
| | cysS | KEGG: abu:Abu_0245 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa) |
| | hypA | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa) |
| | Sdel_1097 | TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: cla:Cla_0790 hydrogenase assembly chaperone HypC. (89 aa) |
| | Sdel_1100 | NikR nickel binding protein; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (137 aa) |
| | Sdel_1101 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (744 aa) |
| | Sdel_1102 | KEGG: abu:Abu_1424 hypothetical protein. (554 aa) |
| | Sdel_1104 | TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: cla:Cla_0714 Ni/Fe hydrogenase, cytochrome b subunit. (225 aa) |
| | Sdel_1105 | PFAM: nickel-dependent hydrogenase large subunit; KEGG: cff:CFF8240_0939 quinone-reactive Ni/Fe- hydrogenase large chain; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (584 aa) |
| | Sdel_1109 | PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: abu:Abu_0778 radical SAM domain-containing protein. (571 aa) |
| | Sdel_1185 | PFAM: Desulfoferrodoxin ferrous iron-binding region; KEGG: tdn:Suden_0990 hypothetical protein. (130 aa) |
| | Sdel_1195 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1059 carbon monoxide-induced hydrogenase, iron-sulfur cluster-binding subunit. (139 aa) |
| | Sdel_1197 | NADH dehydrogenase (quinone); PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: nam:NAMH_1057 carbon monoxide-induced hydrogenase, large subunit. (362 aa) |
| | hypA-2 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (115 aa) |
| | Sdel_1229 | Ferritin Dps family protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (172 aa) |
| | Sdel_1230 | PFAM: homocysteine S-methyltransferase; KEGG: spe:Spro_3471 homocysteine methyltransferase. (311 aa) |
| | Sdel_1278 | PFAM: protein of unknown function DUF111; KEGG: wsu:WS0139 hypothetical protein; Belongs to the LarC family. (408 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (311 aa) |
| | Sdel_1319 | PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; Desulfoferrodoxin Dfx domain protein; KEGG: cju:C8J_0011 rubrerythrin. (216 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) |
| | Sdel_1339 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa) |
| | Sdel_1475 | PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: sfu:Sfum_1310 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. (907 aa) |
| | Sdel_1483 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: wsu:WS1357 cytosine deaminase. (146 aa) |
| | Sdel_1488 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1156 aa) |
| | Sdel_1507 | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (216 aa) |
| | Sdel_1549 | PFAM: Ferritin Dps family protein; KEGG: hhe:HH0210 starvation-inducible DNA-binding protein Dps; Belongs to the Dps family. (145 aa) |
| | Sdel_1554 | PFAM: FeoA family protein; KEGG: abu:Abu_1853 ferrous iron transport protein A. (74 aa) |
| | Sdel_1584 | PFAM: FeoA family protein; KEGG: sun:SUN_0804 ferrous iron transport protein A. (75 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (354 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (611 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (846 aa) |
| | mqnE | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (354 aa) |
| | Sdel_1718 | PFAM: TOBE domain protein; KEGG: sun:SUN_2104 hypothetical protein. (133 aa) |
| | Sdel_1738 | KEGG: tdn:Suden_0396 C-type cytochrome, putative. (112 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (643 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (188 aa) |
| | Sdel_1815 | TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Polynucleotide kinase 3 phosphatase central region; KEGG: nis:NIS_1450 D-glycero-D-manno-heptose 1,7- bisphosphate phosphatase. (169 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (496 aa) |
| | Sdel_1841 | PFAM: AAA ATPase central domain protein; peptidase M41; SMART: AAA ATPase; KEGG: nis:NIS_1070 hypothetical protein. (806 aa) |
| | Sdel_1848 | KEGG: abu:Abu_1549 CiaB protein. (621 aa) |
| | Sdel_1866 | PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: wsu:WS1838 hydrogenase 4 subunit. (579 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (222 aa) |
| | luxS | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (168 aa) |
| | Sdel_1895 | PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: tdn:Suden_1230 heat shock protein DnaJ-like. (91 aa) |
| | Sdel_1898 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase. (1187 aa) |
| | Sdel_1940 | PFAM: nitrogen-fixing NifU domain protein; KEGG: nis:NIS_0251 hypothetical protein. (93 aa) |
| | map | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (252 aa) |
| | rpsZ | Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | Sdel_1971 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (182 aa) |
| | Sdel_1972 | PFAM: FeoA family protein; KEGG: cju:C8J_1311 hypothetical protein. (75 aa) |
| | Sdel_1977 | KEGG: ccv:CCV52592_2067 TPR repeat-containing protein. (347 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (552 aa) |
| | Sdel_2068 | PFAM: TOBE domain protein; regulatory protein LysR; KEGG: wsu:WS1811 molybdenum-pterin-binding protein. (257 aa) |
| | Sdel_2153 | Nitrogen-fixing NifU domain protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (329 aa) |
| | folE | GTP cyclohydrolase I; KEGG: cff:CFF8240_1694 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. (193 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | Sdel_2225 | PFAM: Radical SAM domain protein; KEGG: pca:Pcar_2884 Fe-S oxidoreductase. (286 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (283 aa) |
| | tsaD | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (334 aa) |
| | Sdel_2243 | KEGG: tdn:Suden_0682 hypothetical protein. (197 aa) |
| | Sdel_2254 | methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (151 aa) |
