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| | Sdel_0873 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (135 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (157 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (441 aa) |
| | Sdel_0004 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (355 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (770 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (224 aa) |
| | Sdel_0010 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (317 aa) |
| | Sdel_0027 | PFAM: SirA family protein; KEGG: gbm:Gbem_3433 SirA family protein; Belongs to the sulfur carrier protein TusA family. (70 aa) |
| | Sdel_0031 | KEGG: eba:ebA5899 hypothetical protein. (240 aa) |
| | Sdel_0032 | PFAM: SMC domain protein; SMART: AAA ATPase; KEGG: psb:Psyr_0419 hypothetical protein. (440 aa) |
| | Sdel_0046 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cco:CCC13826_0910 single-stranded-DNA- specific exonuclease RecJ. (527 aa) |
| | Sdel_0049 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (340 aa) |
| | Sdel_0051 | KEGG: cff:CFF8240_0023 hypothetical protein. (54 aa) |
| | Sdel_0052 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: tdn:Suden_1239 anaerobic ribonucleoside triphosphate reductase. (701 aa) |
| | Sdel_0054 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (788 aa) |
| | Sdel_0056 | PFAM: pseudouridine synthase; KEGG: nis:NIS_0055 ribosomal large subunit pseudouridine synthase D. (302 aa) |
| | rlmN | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (358 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (281 aa) |
| | rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (664 aa) |
| | Sdel_0065 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; KEGG: cco:CCC13826_1885 putative peptide ABC transporter, permease protein; Belongs to the pseudouridine synthase RsuA family. (261 aa) |
| | Sdel_0066 | PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: cco:CCC13826_1825 recombination factor protein RarA. (396 aa) |
| | thrS | TIGRFAM: threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Threonyl/alanyl tRNA synthetase SAD; KEGG: cha:CHAB381_0611 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (605 aa) |
| | Sdel_0086 | KEGG: sun:SUN_0071 hypothetical protein. (222 aa) |
| | Sdel_0106 | PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: wsu:WS1033 hypothetical protein. (218 aa) |
| | nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (280 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (298 aa) |
| | Sdel_0162 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (222 aa) |
| | rsmI | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (270 aa) |
| | Sdel_0165 | TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: ccv:CCV52592_0830 RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (227 aa) |
| | Sdel_0170 | PFAM: protein of unknown function UPF0102; KEGG: nis:NIS_1551 hypothetical protein; Belongs to the UPF0102 family. (108 aa) |
| | queH | Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (362 aa) |
| | Sdel_0190 | KEGG: nam:NAMH_1680 hypothetical protein. (146 aa) |
| | Sdel_0198 | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cco:CCC13826_1574 peptide chain release factor 2. (214 aa) |
| | Sdel_0241 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: nam:NAMH_1550 MgpA protein. (314 aa) |
| | Sdel_0249 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (125 aa) |
| | Sdel_0261 | PFAM: Radical SAM domain protein; protein of unknown function DUF752; SMART: Elongator protein 3/MiaB/NifB; KEGG: glo:Glov_3168 conserved hypothetical radical SAM protein. (564 aa) |
| | xseA | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (417 aa) |
| | Sdel_0296 | TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: ccv:CCV52592_0370 flagellar biosynthesis sigma factor. (237 aa) |
| | Sdel_0316 | PFAM: Radical SAM domain protein; KEGG: nis:NIS_0485 MoaA/NifB/PqqE family protein. (303 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (846 aa) |
| | Sdel_0324 | PFAM: protein of unknown function DUF1568; KEGG: sun:SUN_1021 hypothetical protein. (252 aa) |
| | Sdel_0333 | PFAM: protein of unknown function DUF86; KEGG: hha:Hhal_0685 hypothetical protein. (142 aa) |
| | nusG | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (176 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1385 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1507 aa) |
| | rsmG | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (189 aa) |
| | Sdel_0387 | KEGG: xom:XOO_4008 hypothetical protein. (242 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (340 aa) |
| | argS | KEGG: nis:NIS_1495 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (528 aa) |
| | Sdel_0414 | PFAM: DNA/RNA non-specific endonuclease; SMART: DNA/RNA non-specific endonuclease; KEGG: noc:Noc_1834 DNA/RNA non-specific endonuclease. (277 aa) |
| | nusA | Transcription termination factor NusA; Participates in both transcription termination and antitermination. (374 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (438 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (331 aa) |
| | rimO | MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (436 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (546 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (447 aa) |
| | Sdel_0451 | PFAM: integrase family protein; KEGG: abu:Abu_2104 phage integrase; Belongs to the 'phage' integrase family. (416 aa) |
| | Sdel_0471 | TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: tdn:Suden_0387 hypothetical protein. (83 aa) |
| | Sdel_0473 | TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: tdn:Suden_0812 plasmid stabilization system protein. (84 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (918 aa) |
| | Sdel_0488 | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (64 aa) |
| | mutS2 | Smr protein/MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (733 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (319 aa) |
| | Sdel_0527 | PFAM: PP-loop domain protein; KEGG: cco:CCC13826_0928 PP-loop family protein; Belongs to the TtcA family. (250 aa) |
| | Sdel_0528 | KEGG: tdn:Suden_1177 hypothetical protein. (205 aa) |
| | rlmH | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (151 aa) |
| | Sdel_0536 | Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (312 aa) |
| | Sdel_0541 | KEGG: sun:SUN_0644 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. (254 aa) |
| | Sdel_0554 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (938 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (885 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (376 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (189 aa) |
| | lysS | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: nis:NIS_1177 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (506 aa) |
| | uvrC | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (599 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (746 aa) |
| | pheS | KEGG: cff:CFF8240_1254 phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (330 aa) |
| | pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: ccv:CCV52592_0517 phenylalanyl-tRNA synthetase subunit beta. (779 aa) |
| | Sdel_0623 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: abu:Abu_2261 4-methyl-5(beta-hydroxyethyl)- thiazole monophosphate synthesis protein ThiJ. (182 aa) |
| | Sdel_0624 | PFAM: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; KEGG: nis:NIS_0517 DNA mismatch repair ATPase MutS. (977 aa) |
| | Sdel_0632 | KEGG: wsu:WS1983 DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. (1182 aa) |
| | Sdel_0639 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (326 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (392 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (71 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (402 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (582 aa) |
| | Sdel_0658 | SMC domain protein; May be involved in recombinational repair of damaged DNA. (513 aa) |
| | Sdel_0660 | TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: tdn:Suden_1083 TatD-related deoxyribonuclease. (266 aa) |
| | ybeY | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (140 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (642 aa) |
| | Sdel_0680 | PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; KEGG: abu:Abu_1214 glutamylglutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (380 aa) |
| | Sdel_0681 | TIGRFAM: glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; Asn/Gln amidotransferase; KEGG: sun:SUN_1139 glutaminyl-tRNA synthetase. (748 aa) |
| | Sdel_0757 | PFAM: integrase family protein; KEGG: abu:Abu_1324 putative phage integrase; Belongs to the 'phage' integrase family. (419 aa) |
| | Sdel_0760 | Hypothetical protein. (129 aa) |
| | Sdel_0766 | PFAM: Relaxase/mobilization nuclease family protein; KEGG: sun:SUN_2446 DNA relaxase TraI. (521 aa) |
| | Sdel_0767 | Hypothetical protein. (185 aa) |
| | Sdel_0769 | Hypothetical protein. (105 aa) |
| | Sdel_0776 | PFAM: Protein of unknown function DUF2136; KEGG: vsa:VSAL_I1283 hypothetical protein. (99 aa) |
| | Sdel_0778 | PFAM: IstB domain protein ATP-binding protein; KEGG: pol:Bpro_1939 IstB-like ATP-binding protein. (250 aa) |
| | Sdel_0780 | PFAM: Integrase catalytic region; KEGG: maq:Maqu_1328 integrase catalytic subunit. (432 aa) |
| | Sdel_0782 | PFAM: plasmid stabilization system; KEGG: aby:p3ABAYE0047 reversible inhibitor of translation, co-repressor of RelB operon transcription (RelE-like). (98 aa) |
| | Sdel_0788 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (282 aa) |
| | Sdel_0828 | PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: nam:NAMH_1017 exonuclease. (203 aa) |
| | Sdel_0852 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: sun:SUN_1915 ATP-dependent DNA helicase RecG. (614 aa) |
| | Sdel_0862 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (166 aa) |
| | Sdel_0864 | PFAM: DNA polymerase III delta; KEGG: sun:SUN_0430 DNA polymerase III subunit delta. (328 aa) |
| | Sdel_0865 | PFAM: ribonuclease II; Ribonuclease B OB region domain; KEGG: nis:NIS_1162 ribonuclease. (648 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (450 aa) |
| | rny | YmdA/YtgF protein; Endoribonuclease that initiates mRNA decay. (505 aa) |
| | Sdel_0896 | TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: wsu:WS1648 hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (158 aa) |
| | Sdel_0901 | CRISPR-associated helicase Cas3; KEGG: pin:Ping_1586 hypothetical protein; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR- associated HD domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase. (737 aa) |
| | Sdel_0902 | CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (163 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (334 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (103 aa) |
| | Sdel_0908 | PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: nam:NAMH_0210 exonuclease. (292 aa) |
| | Sdel_0922 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_0923 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_0925 | PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: sun:SUN_1076 exonuclease. (246 aa) |
| | Sdel_0930 | PFAM: protein of unknown function DUF86; KEGG: gur:Gura_3202 hypothetical protein. (128 aa) |
| | Sdel_0933 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_0934 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_0941 | KEGG: tdn:Suden_0950 hypothetical protein. (192 aa) |
| | Sdel_0942 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_0943 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_0947 | PFAM: metallophosphoesterase; KEGG: sun:SUN_0725 DNA double-strand break repair protein. (372 aa) |
| | Sdel_0948 | PFAM: SMC domain protein; KEGG: sun:SUN_0726 DNA double-strand break repair protein. (789 aa) |
| | Sdel_0949 | KEGG: dma:DMR_23360 hypothetical protein. (603 aa) |
| | Sdel_0956 | KEGG: intracellular protein transport protein USO1. (1234 aa) |
| | Sdel_0964 | KEGG: tdn:Suden_0950 hypothetical protein. (343 aa) |
| | Sdel_0966 | PFAM: integrase family protein; KEGG: tdn:Suden_0959 phage integrase; Belongs to the 'phage' integrase family. (346 aa) |
| | Sdel_1004 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gsu:GSU2594 transposase/IS protein. (272 aa) |
| | Sdel_1007 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_1008 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | trmA | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (367 aa) |
| | Sdel_1021 | PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: cco:CCC13826_0703 adenylosuccinate lyase. (276 aa) |
| | Sdel_1022 | RNA polymerase sigma-54 factor, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (423 aa) |
| | Sdel_1024 | PFAM: protein of unknown function UPF0079; KEGG: ccv:CCV52592_1981 hypothetical protein. (143 aa) |
| | Sdel_1037 | SMART: AAA ATPase; KEGG: cha:CHAB381_1055 hypothetical protein. (269 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (186 aa) |
| | cysS | KEGG: abu:Abu_0245 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa) |
| | Sdel_1076 | PFAM: protein of unknown function DUF86; KEGG: gur:Gura_4166 hypothetical protein. (117 aa) |
| | Sdel_1112 | PFAM: integrase family protein; KEGG: nis:NIS_0440 phage integrase family site specific recombinase; Belongs to the 'phage' integrase family. (338 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (247 aa) |
| | Sdel_1137 | PFAM: conserved hypothetical protein; KEGG: sun:SUN_1583 hypothetical protein. (251 aa) |
| | Sdel_1144 | TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: nis:NIS_0997 DNA methylase. (191 aa) |
| | Sdel_1150 | PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: tdn:Suden_1612 hypothetical protein. (315 aa) |
| | Sdel_1155 | PFAM: Radical SAM domain protein; KEGG: abu:Abu_0826 hypothetical protein. (405 aa) |
| | Sdel_1156 | KEGG: abu:Abu_0827 hypothetical protein. (243 aa) |
| | truD | tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (361 aa) |
| | Sdel_1208 | PFAM: protein of unknown function DUF86; KEGG: nis:NIS_0575 hypothetical protein. (126 aa) |
| | Sdel_1226 | TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: abu:Abu_1430 ECF subfamily RNA polymerase sigma factor. (155 aa) |
| | Sdel_1231 | PFAM: Abortive phage infection; KEGG: nmu:Nmul_A2605 hypothetical protein. (567 aa) |
| | Sdel_1239 | PFAM: integrase family protein; KEGG: tdn:Suden_0938 phage integrase; Belongs to the 'phage' integrase family. (390 aa) |
| | Sdel_1245 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_1246 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_1253 | PFAM: integrase family protein; KEGG: tdn:Suden_0959 phage integrase. (160 aa) |
| | Sdel_1254 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_1255 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_1257 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_1258 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_1263 | KEGG: nis:NIS_1081 tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (414 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (373 aa) |
| | xerH | Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerH subfamily. (353 aa) |
| | hisS | KEGG: tdn:Suden_1130 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S). (402 aa) |
| | Sdel_1304 | TIGRFAM: tRNA 2-selenouridine synthase; SMART: Rhodanese domain protein; KEGG: cco:CCC13826_0142 tRNA 2-selenouridine synthase; Belongs to the SelU family. (342 aa) |
| | Sdel_1310 | KEGG: cco:CCC13826_0148 hypothetical protein. (783 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (567 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (876 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (213 aa) |
| | cmoB | Methyltransferase putative; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (300 aa) |
| | Sdel_1366 | KEGG: cco:CCC13826_2036 hypothetical protein. (341 aa) |
| | cmoA | Methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (234 aa) |
| | Sdel_1370 | KEGG: nam:NAMH_1087 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. (238 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (648 aa) |
| | Sdel_1375 | KEGG: abu:Abu_1201 putative DNA polymerase III delta prime subunit HolB. (208 aa) |
| | rppH | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (156 aa) |
| | Sdel_1408 | PFAM: restriction endonuclease; KEGG: afw:Anae109_1084 restriction endonuclease. (302 aa) |
| | Sdel_1416 | KEGG: sun:SUN_0982 hypothetical protein. (442 aa) |
| | Sdel_1419 | KEGG: tcx:Tcr_0083 hypothetical protein. (1215 aa) |
| | Sdel_1422 | PFAM: protein of unknown function DUF195; KEGG: tdn:Suden_0237 hypothetical protein. (428 aa) |
| | rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (304 aa) |
| | Sdel_1456 | PFAM: beta-lactamase domain protein; RNA- metabolising metallo-beta-lactamase; KEGG: tdn:Suden_1267 RNA-metabolising metallo-beta- lactamase. (464 aa) |
| | Sdel_1483 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: wsu:WS1357 cytosine deaminase. (146 aa) |
| | Sdel_1495 | TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: rfe:RF_0334 hypothetical protein. (98 aa) |
| | Sdel_1498 | PFAM: PilT protein domain protein; KEGG: hhe:HH0272 hypothetical protein. (181 aa) |
| | Sdel_1501 | PFAM: protein of unknown function DUF450; N-6 DNA methylase; KEGG: sun:SUN_2234 hypothetical protein. (974 aa) |
| | glyS | KEGG: nis:NIS_0732 glycyl-tRNA synthetase subunit beta; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase beta subunit. (683 aa) |
| | Sdel_1506 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sun:SUN_1850 hypothetical protein. (310 aa) |
| | trmL | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (156 aa) |
| | Sdel_1513 | PFAM: Polynucleotide adenylyltransferase region; KEGG: nis:NIS_0728 RNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (375 aa) |
| | Sdel_1519 | PFAM: protein of unknown function DUF86; KEGG: sun:SUN_0149 hypothetical protein. (121 aa) |
| | Sdel_1523 | TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; KEGG: cti:pRALTA_0043 toxin of the YoeB-YefM toxin- antitoxin system. (89 aa) |
| | Sdel_1525 | PFAM: pseudouridine synthase; KEGG: sun:SUN_0745 ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. (194 aa) |
| | Sdel_1531 | Type II site-specific deoxyribonuclease; PFAM: Dam-replacing family protein; KEGG: ftn:FTN_1698 Dam-replacing family protein. (255 aa) |
| | Sdel_1535 | KEGG: sun:SUN_2266 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: HRDC domain protein; DEAD/DEAH box helicase domain protein; RQC domain; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein. (596 aa) |
| | rpoD | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (617 aa) |
| | Sdel_1549 | PFAM: Ferritin Dps family protein; KEGG: hhe:HH0210 starvation-inducible DNA-binding protein Dps; Belongs to the Dps family. (145 aa) |
| | Sdel_1587 | PFAM: protein of unknown function DUF891; KEGG: sun:SUN_2445 hypothetical protein. (118 aa) |
| | Sdel_1595 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (476 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (611 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa) |
| | Sdel_1605 | KEGG: ccv:CCV52592_0726 DNA polymerase III subunit epsilon; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (260 aa) |
| | Sdel_1611 | PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: nis:NIS_1458 endonuclease III. (221 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (989 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase class I (M); KEGG: abu:Abu_0402 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (815 aa) |
| | csrA | Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (75 aa) |
| | Sdel_1632 | PFAM: pseudouridylate synthase TruB domain protein; KEGG: cff:CFF8240_0715 tRNA pseudouridine synthase B; Belongs to the pseudouridine synthase TruB family. (275 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (230 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (179 aa) |
| | Sdel_1651 | PFAM: pseudouridine synthase; KEGG: nis:NIS_1506 ribosomal large subunit pseudouridine synthase D. (242 aa) |
| | glyQ | KEGG: nis:NIS_1511 glycyl-tRNA synthetase subunit alpha; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit. (285 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (846 aa) |
| | Sdel_1678 | KEGG: nam:NAMH_1677 hypothetical protein; TIGRFAM: competence protein ComEA helix-hairpin- helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1. (80 aa) |
| | Sdel_1721 | PFAM: Restriction endonuclease, type II, NgoPII; KEGG: ngk:NGK_2480 NgoPII restriction and modification. (283 aa) |
| | Sdel_1722 | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngk:NGK_2479 modification methylase NgoPII; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (335 aa) |
| | nusB | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (136 aa) |
| | Sdel_1755 | KEGG: cco:CCC13826_0775 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib. (321 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (414 aa) |
| | Sdel_1796 | PFAM: ATP dependent DNA ligase; KEGG: msu:MS0939 DNA ligase. (271 aa) |
| | Sdel_1800 | PFAM: 3'-5' exonuclease, PolB-like; KEGG: cco:CCC13826_0469 large-conductance mechanosensitive channel. (262 aa) |
| | mnmG | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (624 aa) |
| | Sdel_1894 | PFAM: DsrE family protein; KEGG: nam:NAMH_1288 hypothetical protein. (117 aa) |
| | Sdel_1895 | PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: tdn:Suden_1230 heat shock protein DnaJ-like. (91 aa) |
| | Sdel_1911 | KEGG: tdn:Suden_0088 hypothetical protein. (780 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (337 aa) |
| | Sdel_1971 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (182 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (227 aa) |
| | Sdel_1976 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (142 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (552 aa) |
| | Sdel_1995 | PFAM: integrase family protein; KEGG: sun:SUN_1438 phage integrase family site specific recombinase; Belongs to the 'phage' integrase family. (359 aa) |
| | Sdel_1998 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gme:Gmet_3281 transposase/IS protein. (273 aa) |
| | Sdel_1999 | PFAM: Integrase catalytic region; KEGG: lpc:LPC_1389 putative transposase for insertion sequence element IS5376. (368 aa) |
| | Sdel_2012 | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: tdn:Suden_0121 DNA (cytosine-5-)- methyltransferase. (398 aa) |
| | Sdel_2013 | KEGG: nis:NIS_0569 hypothetical protein. (414 aa) |
| | Sdel_2015 | PFAM: plasmid maintenance system killer; KEGG: nis:NIS_1330 plasmid stabilization system protein. (91 aa) |
| | Sdel_2054 | TIGRFAM: selenium metabolism protein YedF; PFAM: SirA family protein; KEGG: nam:NAMH_1292 hypothetical protein; Belongs to the sulfur carrier protein TusA family. (196 aa) |
| | Sdel_2081 | PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: tdn:Suden_0827 response regulator receiver domain-containing protein. (224 aa) |
| | selA | L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (445 aa) |
| | Sdel_2127 | KEGG: abu:Abu_1507 heavy-metal transport protein. (110 aa) |
| | Sdel_2129 | Site-specific DNA-methyltransferase (adenine- specific); PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: tdn:Suden_0130 site-specific DNA- methyltransferase (adenine-specific). (323 aa) |
| | mnmA | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (339 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (694 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (347 aa) |
| | tsaD | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (334 aa) |
| | Sdel_2254 | methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (151 aa) |
| | Sdel_2264 | PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; KEGG: cff:CFF8240_1240 RNA-binding region RNP-1. (101 aa) |
