node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sdel_1681 | guaA | Sdel_1681 | Sdel_0595 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: abu:Abu_2004 anthranilate synthase component II. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.435 |
Sdel_1681 | hisH | Sdel_1681 | Sdel_1765 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: abu:Abu_2004 anthranilate synthase component II. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.404 |
Sdel_2216 | guaA | Sdel_2216 | Sdel_0595 | TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: tdn:Suden_0186 asparagine synthase, glutamine- hydrolyzing. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.491 |
carA | guaA | Sdel_1923 | Sdel_0595 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.424 |
carA | purF | Sdel_1923 | Sdel_0174 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.964 |
carA | purQ | Sdel_1923 | Sdel_1404 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.951 |
guaA | Sdel_1681 | Sdel_0595 | Sdel_1681 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: abu:Abu_2004 anthranilate synthase component II. | 0.435 |
guaA | Sdel_2216 | Sdel_0595 | Sdel_2216 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: tdn:Suden_0186 asparagine synthase, glutamine- hydrolyzing. | 0.491 |
guaA | carA | Sdel_0595 | Sdel_1923 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.424 |
guaA | hisH | Sdel_0595 | Sdel_1765 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.492 |
guaA | purF | Sdel_0595 | Sdel_0174 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.719 |
guaA | purQ | Sdel_0595 | Sdel_1404 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.707 |
guaA | pyrG | Sdel_0595 | Sdel_0045 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.960 |
hisH | Sdel_1681 | Sdel_1765 | Sdel_1681 | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: abu:Abu_2004 anthranilate synthase component II. | 0.404 |
hisH | guaA | Sdel_1765 | Sdel_0595 | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.492 |
purF | carA | Sdel_0174 | Sdel_1923 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.964 |
purF | guaA | Sdel_0174 | Sdel_0595 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.719 |
purF | purQ | Sdel_0174 | Sdel_1404 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.995 |
purF | pyrG | Sdel_0174 | Sdel_0045 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.549 |
purQ | carA | Sdel_1404 | Sdel_1923 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.951 |