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| | ilvD | KEGG: cco:CCC13826_0012 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (559 aa) |
| | Sdel_0044 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sun:SUN_1936 UTP--glucose-1-phosphate uridylyltransferase. (289 aa) |
| | Sdel_0055 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; KEGG: wsu:WS0416 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (442 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | purM | KEGG: nam:NAMH_0144 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo- ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (331 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (247 aa) |
| | Sdel_0091 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: ccv:CCV52592_1540 glycerate dehydrogenase. (310 aa) |
| | Sdel_0094 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (120 aa) |
| | Sdel_0115 | PFAM: conserved hypothetical protein; KEGG: abu:Abu_0048 hypothetical protein. (170 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (298 aa) |
| | Sdel_0154 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: ccv:CCV52592_0818 prenyltransferase; Belongs to the UbiA prenyltransferase family. (289 aa) |
| | Sdel_0169 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; dihydrodipicolinate reductase; KEGG: nis:NIS_1553 homoserine dehydrogenase. (423 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (445 aa) |
| | hisI | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: nis:NIS_1544 histidine biosynthesis bifunctional protein HisI; In the N-terminal section; belongs to the PRA-CH family. (227 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (304 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (263 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) |
| | Sdel_0208 | KEGG: abu:Abu_0221 3-phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. (206 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (331 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (401 aa) |
| | Sdel_0216 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: cff:CFF8240_0269 chorismate mutase/prephenate dehydratase. (355 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: wsu:WS2000 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (610 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (330 aa) |
| | Sdel_0230 | PFAM: Prephenate dehydrogenase; KEGG: nis:NIS_0406 prephenate dehydrogenase. (275 aa) |
| | plsY | Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (208 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa) |
| | Sdel_0251 | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; KEGG: nis:NIS_0424 riboflavin biosynthesis protein RibG. (338 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (241 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (214 aa) |
| | Sdel_0289 | PFAM: amidohydrolase; KEGG: nam:NAMH_1355 amidohydrolase. (408 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (160 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (309 aa) |
| | Sdel_0312 | PFAM: Aldehyde Dehydrogenase; KEGG: abu:Abu_0378 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (340 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa) |
| | Sdel_0325 | PFAM: Lactate/malate dehydrogenase; KEGG: vpa:VPA0147 lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (309 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (187 aa) |
| | Sdel_0381 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tdn:Suden_0385 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (325 aa) |
| | Sdel_0382 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | Sdel_0384 | KEGG: cco:CCC13826_0887 coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa) |
| | Sdel_0385 | PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: cha:CHAB381_1616 iron-sulfur cluster-binding domain-containing protein. (420 aa) |
| | Sdel_0394 | PFAM: Fumarate reductase respiratory complex; KEGG: abu:Abu_0301 fumarate reductase cytochrome b- 556 subunit. (260 aa) |
| | Sdel_0395 | KEGG: ccv:CCV52592_2205 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (661 aa) |
| | Sdel_0396 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_0424 fumarate reductase iron- sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (240 aa) |
| | panB | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (278 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (246 aa) |
| | Sdel_0421 | KEGG: tdn:Suden_1754 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: cjr:CJE1589 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | Sdel_0423 | PFAM: triosephosphate isomerase; KEGG: abu:Abu_2134 triosephosphate isomerase. (237 aa) |
| | Sdel_0424 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cco:CCC13826_0513 enoyl-(acyl carrier protein) reductase. (273 aa) |
| | panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (273 aa) |
| | Sdel_0441 | PFAM: Asparaginase/glutaminase; KEGG: abu:Abu_1580 putative asparaginase. (164 aa) |
| | Sdel_0444 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (228 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (369 aa) |
| | Sdel_0497 | Malate dehydrogenase (acceptor); PFAM: FAD dependent oxidoreductase; Malate:quinone- oxidoreductase; KEGG: sun:SUN_0432 malate:quinone oxidoreductase. (446 aa) |
| | Sdel_0501 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (481 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (255 aa) |
| | Sdel_0525 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: abu:Abu_1586 malonyl coenzyme A-(acyl carrier protein) transacylase. (307 aa) |
| | Sdel_0526 | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (231 aa) |
| | Sdel_0529 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: nis:NIS_1201 glutamate synthase (NADPH), large chain. (1474 aa) |
| | Sdel_0530 | TIGRFAM: glutamate synthase, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tdn:Suden_1175 glutamate synthase subunit beta. (461 aa) |
| | Sdel_0531 | PFAM: inositol monophosphatase; KEGG: nis:NIS_1199 inositol monophosphatase family protein. (241 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) |
| | Sdel_0567 | PFAM: iron-containing alcohol dehydrogenase; KEGG: gur:Gura_3532 iron-containing alcohol dehydrogenase. (383 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (263 aa) |
| | Sdel_0572 | Anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: tdn:Suden_1277 anthranilate synthase. (470 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (203 aa) |
| | Sdel_0596 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (214 aa) |
| | purD | KEGG: nis:NIS_1337 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP- grasp (A) domain; Phosphoribosylglycinamide synthetase, N- domain; Phosphoribosylglycinamide synthetase, C-domain; ATP-dependent carboxylate-amine ligase domain protein ATP- grasp; Belongs to the GARS family. (424 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (525 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: tdn:Suden_0866 argininosuccinate lyase. (463 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (428 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (277 aa) |
| | Sdel_0615 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_0512 D-3-phosphoglycerate dehydrogenase. (528 aa) |
| | Sdel_0628 | PFAM: conserved hypothetical protein; KEGG: abu:Abu_0048 hypothetical protein. (171 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: abu:Abu_0977 imidazoleglycerol-phosphate dehydratase. (190 aa) |
| | Sdel_0668 | PFAM: GCN5-related N-acetyltransferase; KEGG: tdn:Suden_1075 acetyltransferase; Belongs to the acetyltransferase family. (152 aa) |
| | fbp | Fructose-bisphosphatase; PFAM: Inositol phosphatase/fructose-16- bisphosphatase; KEGG: abu:Abu_1219 fructose-1,6-bisphosphatase. (278 aa) |
| | Sdel_0680 | PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; KEGG: abu:Abu_1214 glutamylglutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (380 aa) |
| | Sdel_0749 | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (295 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (731 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (401 aa) |
| | Sdel_0842 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: nam:NAMH_1207 ribose 5-phosphate isomerase B. (142 aa) |
| | hemL | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: tdn:Suden_1109 glutamate-1-semialdehyde aminotransferase. (428 aa) |
| | mqnC | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (350 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | Sdel_0875 | PFAM: aminotransferase class-III; KEGG: abu:Abu_0259 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (395 aa) |
| | ribB-2 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. (340 aa) |
| | Sdel_0970 | TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; KEGG: nis:NIS_0828 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (853 aa) |
| | Sdel_0972 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa) |
| | Sdel_1014 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cco:CCC13826_1403 threonine dehydratase. (403 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (327 aa) |
| | argG | KEGG: cco:CCC13826_1219 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa) |
| | Sdel_1037 | SMART: AAA ATPase; KEGG: cha:CHAB381_1055 hypothetical protein. (269 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | Sdel_1081 | PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: cha:CHAB381_1142 2-oxoglutarate-acceptor oxidoreductase subunit OorC. (185 aa) |
| | Sdel_1082 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cff:CFF8240_0907 2-oxoglutarate-acceptor oxidoreductase subunit OorB. (277 aa) |
| | Sdel_1083 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cla:Cla_0816 2-oxoglutarate:acceptor oxidoreductase, OorA subunit. (377 aa) |
| | Sdel_1084 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sun:SUN_0578 2-oxoglutarate-acceptor oxidoreductase subunit OorD. (105 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa) |
| | Sdel_1089 | KEGG: son:SO_2629 isocitrate dehydrogenase, NADP- dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (745 aa) |
| | Sdel_1092 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: nis:NIS_1852 HAD-superfamily hydrolase. (212 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: sun:SUN_1935 glucose-6-phosphate isomerase; Belongs to the GPI family. (422 aa) |
| | gpsA | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: abu:Abu_0029 NAD(P)H-dependent glycerol-3- phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (296 aa) |
| | Sdel_1178 | L-asparaginase, type II; KEGG: cff:CFF8240_1025 L-asparaginase II; TIGRFAM: L-asparaginase, type II; PFAM: Asparaginase/glutaminase; Belongs to the asparaginase 1 family. (347 aa) |
| | Sdel_1184 | Heterodisulfide reductase subunit B-like protein; KEGG: sun:SUN_1202 succinate dehydrogenase/fumarate reductase, subunit C. (281 aa) |
| | Sdel_1200 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: nam:NAMH_1054 glutamate synthase [NADPH] small chain. (473 aa) |
| | Sdel_1201 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: rfr:Rfer_1248 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (306 aa) |
| | Sdel_1230 | PFAM: homocysteine S-methyltransferase; KEGG: spe:Spro_3471 homocysteine methyltransferase. (311 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (348 aa) |
| | Sdel_1275 | KEGG: sun:SUN_0573 fumarate/tartrate hydratase, alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (283 aa) |
| | Sdel_1276 | TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: nam:NAMH_1232 C-terminal fumarate hydratase, class I. (187 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (175 aa) |
| | Sdel_1290 | KEGG: tdn:Suden_1133 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein. (237 aa) |
| | Sdel_1291 | PFAM: aminotransferase class I and II; KEGG: nis:NIS_0815 aspartate aminotransferase. (389 aa) |
| | Sdel_1292 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pca:Pcar_2295 putative oxidoreductase. (398 aa) |
| | Sdel_1295 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. (156 aa) |
| | Sdel_1296 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: nis:NIS_0810 acetolactate synthase 3 catalytic subunit. (563 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: sun:SUN_1695 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (262 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (411 aa) |
| | Sdel_1315 | Phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: nam:NAMH_1412 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II. (453 aa) |
| | Sdel_1321 | TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: abu:Abu_0317 carboxylyase-related protein; Belongs to the UbiD family. (602 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (314 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (433 aa) |
| | Sdel_1327 | PFAM: Polyprenyl synthetase; KEGG: abu:Abu_0386 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (298 aa) |
| | Sdel_1332 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: abu:Abu_2299 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) |
| | Sdel_1339 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (283 aa) |
| | Sdel_1352 | KEGG: abu:Abu_2067 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (498 aa) |
| | Sdel_1369 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: cco:CCC13826_2025 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (293 aa) |
| | Sdel_1377 | KEGG: cju:C8J_0544 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (400 aa) |
| | Sdel_1379 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (351 aa) |
| | purC | KEGG: cla:Cla_0709 phosphoribosylaminoimidazole- succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole- succinocarboxamide synthase; PFAM: SAICAR synthetase. (237 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (81 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | Sdel_1406 | KEGG: ccv:CCV52592_2001 1-acyl-sn-glycerol-3- phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (229 aa) |
| | Sdel_1431 | PFAM: peptidase M48 Ste24p; KEGG: abu:Abu_0531 M48 family peptidase. (404 aa) |
| | purH | KEGG: cco:CCC13826_1632 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region. (510 aa) |
| | Sdel_1447 | PFAM: aminotransferase class I and II; KEGG: gbm:Gbem_0056 aminotransferase class I and II. (379 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (733 aa) |
| | Sdel_1474 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: sfu:Sfum_1311 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (784 aa) |
| | Sdel_1488 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1156 aa) |
| | ppnP | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (103 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (162 aa) |
| | acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa) |
| | Sdel_1592 | D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: cha:CHAB381_1615 glycolate oxidase, subunit GlcD. (459 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (354 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: nis:NIS_0321 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (195 aa) |
| | Sdel_1607 | KEGG: abu:Abu_0860 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (213 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (396 aa) |
| | Sdel_1624 | KEGG: abu:Abu_0445 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. (404 aa) |
| | Sdel_1630 | 4-diphosphocytidyl-2C-methyl-D-erythritolkinase; KEGG: tdn:Suden_0440 4-diphosphocytidyl-2-C-methyl- D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; Belongs to the GHMP kinase family. IspE subfamily. (258 aa) |
| | Sdel_1642 | PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. (390 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | Sdel_1660 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: ccv:CCV52592_0277 histidinol phosphate phosphatase, HisJ; Belongs to the PHP hydrolase family. HisK subfamily. (259 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (312 aa) |
| | Sdel_1681 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: abu:Abu_2004 anthranilate synthase component II. (189 aa) |
| | Sdel_1684 | PFAM: phosphoribosyltransferase; KEGG: cla:Cla_0429 nucleotide phosphoribosyltransferase, putative. (149 aa) |
| | mqnE | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (354 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa) |
| | ispDF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (374 aa) |
| | Sdel_1709 | PFAM: ATP-sulfurylase; KEGG: nis:NIS_0593 sulfate adenylyltransferase. (397 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (248 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (184 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (520 aa) |
| | Sdel_1759 | KEGG: cff:CFF8240_1345 CDP-diacylglycerol--serine O- phosphatidyltransferse; TIGRFAM: CDP-diacylglycerol/serine O- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (244 aa) |
| | Sdel_1760 | PFAM: phosphatidylserine decarboxylase-related; KEGG: ccv:CCV52592_1195 phosphatidylserine decarboxylase. (219 aa) |
| | hisA | KEGG: nis:NIS_1411 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. (240 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (203 aa) |
| | Sdel_1770 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (190 aa) |
| | Sdel_1785 | TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; KEGG: abu:Abu_1816 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (346 aa) |
| | Sdel_1786 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (292 aa) |
| | Sdel_1791 | KEGG: sun:SUN_0324 mannose-1-phosphate guanylyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (443 aa) |
| | Sdel_1797 | TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: abu:Abu_1816 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (338 aa) |
| | Sdel_1798 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (287 aa) |
| | Sdel_1799 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: sun:SUN_1934 phosphomannomutase. (456 aa) |
| | Sdel_1825 | KEGG: abu:Abu_2211 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. (202 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (312 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa) |
| | Sdel_1837 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (496 aa) |
| | Sdel_1898 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase. (1187 aa) |
| | Sdel_1899 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sun:SUN_0197 HAD-superfamily hydrolase. (212 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (386 aa) |
| | Sdel_1932 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: dal:Dalk_1233 HAD-superfamily hydrolase, subfamily IA, variant 1. (218 aa) |
| | Sdel_1933 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (656 aa) |
| | Sdel_1934 | PFAM: Polyprenyl synthetase; KEGG: wsu:WS1679 geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (286 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (121 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (358 aa) |
| | Sdel_2006 | L-asparaginase, type II; KEGG: wsu:WS0660 periplasmic L-asparaginase II; TIGRFAM: L-asparaginase, type II; PFAM: Asparaginase/glutaminase; Belongs to the asparaginase 1 family. (348 aa) |
| | Sdel_2101 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: dar:Daro_4188 3-ketoacyl-(acyl-carrier- protein) reductase. (229 aa) |
| | Sdel_2109 | KEGG: dar:Daro_2373 acyl carrier protein. (89 aa) |
| | Sdel_2124 | KEGG: pca:Pcar_2651 acyl-carrier protein. (83 aa) |
| | Sdel_2142 | PFAM: Saccharopine dehydrogenase; KEGG: cco:CCC13826_0747 saccharopine dehydrogenase. (404 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (192 aa) |
| | mqnA | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (221 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | Sdel_2198 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (443 aa) |
| | Sdel_2199 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa) |
| | Sdel_2216 | TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: tdn:Suden_0186 asparagine synthase, glutamine- hydrolyzing. (596 aa) |
| | Sdel_2222 | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: acp:A2cp1_4443 dTDP-glucose 4,6-dehydratase. (345 aa) |
| | Sdel_2232 | KEGG: cco:CCC13826_2287 citrate (Si)-synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (428 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa) |
| | mqnD | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (288 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (355 aa) |
| | Sdel_2250 | PFAM: phosphatidate cytidylyltransferase; KEGG: nis:NIS_1667 phosphatidate cytidylyltransferase; Belongs to the CDS family. (254 aa) |
| | Sdel_2253 | KEGG: glycerate kinase; K00865 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (380 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (421 aa) |
| | Sdel_2263 | Phospholipase A(2); Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (334 aa) |
