STRINGSTRING
trpB trpB Taci_0141 Taci_0141 Taci_0142 Taci_0142 Taci_0266 Taci_0266 Taci_0267 Taci_0267 Taci_0506 Taci_0506 Taci_0567 Taci_0567 upp upp cysS cysS Taci_1035 Taci_1035 asd asd Taci_1239 Taci_1239 thrB thrB Taci_1241 Taci_1241 glyA glyA Taci_1423 Taci_1423 metXA metXA Taci_1506 Taci_1506 Taci_1535 Taci_1535 Taci_1548 Taci_1548 Taci_1652 Taci_1652 Taci_1720 Taci_1720 Taci_1733 Taci_1733 Taci_1734 Taci_1734
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa)
Taci_0141PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12- binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: gsu:GSU2921 5-methyltetrahydrofolate- homocysteine methyltransferase, truncation. (816 aa)
Taci_0142KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (298 aa)
Taci_0266KEGG: bha:BH2497 L-serine dehydratase beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, beta subunit; PFAM: serine dehydratase beta chain; amino acid- binding ACT domain protein. (224 aa)
Taci_0267KEGG: bcr:BCAH187_A4271 L-serine dehydratase, iron- sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, alpha subunit; PFAM: serine dehydratase alpha chain. (290 aa)
Taci_0506PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rlt:Rleg2_5063 homoserine dehydrogenase. (336 aa)
Taci_0567PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cysteine synthase; K01738 cysteine synthase. (301 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (370 aa)
cysSKEGG: bcy:Bcer98_0084 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (468 aa)
Taci_1035KEGG: sfu:Sfum_0366 adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD- binding; S-adenosyl-L-homocysteine hydrolase. (411 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa)
Taci_1239KEGG: mxa:MXAN_3466 aspartate kinase, monofunctional class; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (410 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (314 aa)
Taci_1241TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bha:BH3421 threonine synthase. (344 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
Taci_1423PFAM: aminotransferase class I and II; KEGG: ypm:YP_2630 putative aminotransferase. (399 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (364 aa)
Taci_1506O-acetylhomoserineaminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: msl:Msil_0179 O-acetylhomoserine/O- acetylserine sulfhydrylase. (476 aa)
Taci_1535Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: gme:Gmet_0270 L-threonine aldolase. (342 aa)
Taci_1548PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: ppw:PputW619_3319 L-serine ammonia-lyase. (519 aa)
Taci_1652KEGG: gbm:Gbem_0049 pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; aminotransferase class-III; aromatic amino acid beta- eliminating lyase/threonine aldolase. (393 aa)
Taci_1720PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcb:BCB4264_A2424 threonine ammonia-lyase, catabolic. (330 aa)
Taci_1733KEGG: bmn:BMA10247_1438 serine O-acetyltransferase. (215 aa)
Taci_1734TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pca:Pcar_2430 cysteine synthase A. (301 aa)
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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