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Taci_0016 Taci_0016 rbsK rbsK deoC deoC Taci_0152 Taci_0152 Taci_0218 Taci_0218 Taci_0234 Taci_0234 Taci_0235 Taci_0235 nagB nagB Taci_0237 Taci_0237 eno eno Taci_0332 Taci_0332 Taci_0485 Taci_0485 Taci_0486 Taci_0486 Taci_0535 Taci_0535 rbsK-2 rbsK-2 Taci_0565 Taci_0565 pdxS pdxS Taci_0794 Taci_0794 Taci_0824 Taci_0824 Taci_0833 Taci_0833 glmM glmM glmS glmS Taci_0889 Taci_0889 pgk pgk tpiA tpiA Taci_1013 Taci_1013 Taci_1130 Taci_1130 tal tal pfkA pfkA gpmA gpmA Taci_1459 Taci_1459 Taci_1460 Taci_1460 Taci_1549 Taci_1549 Taci_1560 Taci_1560 Taci_1664 Taci_1664 Taci_1681 Taci_1681 Taci_1682 Taci_1682 Taci_1683 Taci_1683 Taci_1684 Taci_1684 Taci_1714 Taci_1714 Taci_1715 Taci_1715 Taci_1716 Taci_1716 Taci_1717 Taci_1717 pfp pfp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Taci_0016KEGG: dol:Dole_2031 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-6-phosphate isomerase type II. (447 aa)
rbsKPfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (308 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (221 aa)
Taci_0152PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: aeh:Mlg_2089 fructose-bisphosphate aldolase. (351 aa)
Taci_0218PFAM: ketose-bisphosphate aldolase class-II; KEGG: gbm:Gbem_1007 fructose/tagatose bisphosphate aldolase-like protein. (421 aa)
Taci_0234TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: cvi:CV_0980 phosphoenolpyruvate-protein phosphotransferase. (158 aa)
Taci_0235KEGG: ypb:YPTS_2252 hypothetical protein. (312 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (250 aa)
Taci_0237KEGG: sun:SUN_2245 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase. (375 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
Taci_0332PFAM: phosphotransferase system lactose/cellobiose- specific IIB subunit; KEGG: bat:BAS5064 PTS system, cellobiose-specific IIB component. (99 aa)
Taci_0485PFAM: Transketolase domain protein; KEGG: gsu:GSU2919 transketolase, N-terminal subunit. (277 aa)
Taci_0486PFAM: Transketolase domain protein; Transketolase central region; KEGG: pca:Pcar_2719 transketolase, C-terminal subunit. (313 aa)
Taci_0535PFAM: ROK family protein; KEGG: gbm:Gbem_1326 ROK family protein. (296 aa)
rbsK-2PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (295 aa)
Taci_0565PFAM: SNO glutamine amidotransferase; KEGG: dds:Ddes_1897 SNO glutamine amidotransferase. (188 aa)
pdxSPyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (294 aa)
Taci_0794PFAM: phosphoglucose isomerase (PGI); KEGG: afw:Anae109_2086 glucose-6-phosphate isomerase. (441 aa)
Taci_0824TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: bha:BH0827 fructose 1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (310 aa)
Taci_0833TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; KEGG: bha:BH3163 pyruvate kinase; Belongs to the pyruvate kinase family. (582 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
Taci_0889KEGG: bha:BH3560 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: bsu:BSU33930 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (274 aa)
Taci_1013Fructose-1,6-bisphosphatase, class II; KEGG: dvl:Dvul_1592 fructose 1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein. (328 aa)
Taci_1130PFAM: Transketolase central region; Transketolase domain protein; KEGG: sfu:Sfum_1302 transketolase. (648 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
Taci_1459TIGRFAM: PTS system, glucose-specific IIBC subunit; PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; sugar- specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; KEGG: bha:BH0844 PTS system, glucose-specific enzyme II, A component. (658 aa)
Taci_1460Transcriptional antiterminator, BglG; PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: bha:BH0845 transcriptional antiterminator. (285 aa)
Taci_1549Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: tmz:Tmz1t_0468 phosphocarrier, HPr family. (86 aa)
Taci_1560Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (585 aa)
Taci_1664KEGG: bha:BH2502 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
Taci_1681KEGG: bsu:BSU35790 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I. (312 aa)
Taci_1682Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: bcy:Bcer98_1170 PTS system, fructose subfamily, IIC subunit. (149 aa)
Taci_1683PTS modulated transcriptional regulator, MtlR family; PFAM: PRD domain protein; phosphoenolpyruvate- dependent sugar phosphotransferase system EIIA 2; Helix- turn-helix type 11 domain protein; KEGG: bcy:Bcer98_1169 transcriptional antiterminator, BglG. (646 aa)
Taci_1684TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: bcy:Bcer98_1170 PTS system, fructose subfamily, IIC subunit. (464 aa)
Taci_1714Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: bcy:Bcer98_2396 DeoR family transcriptional regulator. (256 aa)
Taci_1715TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: dac:Daci_2664 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (310 aa)
Taci_1716Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: bcy:Bcer98_2394 PTS system, fructose subfamily, IIC subunit. (154 aa)
Taci_1717TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: bte:BTH_II0908 protein-N p-phosphohistidine- sugar phosphotransferase. (456 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (416 aa)
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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