STRINGSTRING
Taci_0020 Taci_0020 Taci_0021 Taci_0021 Taci_0142 Taci_0142 Taci_0152 Taci_0152 Taci_0188 Taci_0188 Taci_0215 Taci_0215 Taci_0217 Taci_0217 Taci_0218 Taci_0218 Taci_0266 Taci_0266 Taci_0267 Taci_0267 Taci_0269 Taci_0269 Taci_0288 Taci_0288 Taci_0289 Taci_0289 Taci_0290 Taci_0290 Taci_0301 Taci_0301 Taci_0302 Taci_0302 Taci_0303 Taci_0303 eno eno Taci_0474 Taci_0474 Taci_0485 Taci_0485 Taci_0486 Taci_0486 Taci_0535 Taci_0535 Taci_0585 Taci_0585 Taci_0586 Taci_0586 Taci_0587 Taci_0587 Taci_0588 Taci_0588 Taci_0614 Taci_0614 Taci_0615 Taci_0615 Taci_0794 Taci_0794 Taci_0803 Taci_0803 Taci_0810 Taci_0810 fhs fhs Taci_0833 Taci_0833 Taci_0889 Taci_0889 tpiA tpiA Taci_0964 Taci_0964 Taci_0965 Taci_0965 Taci_0966 Taci_0966 Taci_0967 Taci_0967 Taci_1013 Taci_1013 Taci_1059 Taci_1059 prs prs folD folD ackA ackA Taci_1130 Taci_1130 tal tal pfkA pfkA glyA glyA gpmA gpmA Taci_1436 Taci_1436 Taci_1548 Taci_1548 Taci_1664 Taci_1664 Taci_1678 Taci_1678 Taci_1720 Taci_1720 Taci_1733 Taci_1733 Taci_1734 Taci_1734 pfp pfp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Taci_0020TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: afr:AFE_0423 aconitate hydratase, putative. (644 aa)
Taci_0021KEGG: sfu:Sfum_3896 isocitrate dehydrogenase, NADP- dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase. (417 aa)
Taci_0142KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (298 aa)
Taci_0152PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: aeh:Mlg_2089 fructose-bisphosphate aldolase. (351 aa)
Taci_0188PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: mms:mma_0278 glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (414 aa)
Taci_0215Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bha:BH3168 malic enzyme (malate dehydrogenase). (392 aa)
Taci_0217KEGG: gsu:GSU0910 aldehyde:ferredoxin oxidoreductase, tungsten-containing; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (615 aa)
Taci_0218PFAM: ketose-bisphosphate aldolase class-II; KEGG: gbm:Gbem_1007 fructose/tagatose bisphosphate aldolase-like protein. (421 aa)
Taci_0266KEGG: bha:BH2497 L-serine dehydratase beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, beta subunit; PFAM: serine dehydratase beta chain; amino acid- binding ACT domain protein. (224 aa)
Taci_0267KEGG: bcr:BCAH187_A4271 L-serine dehydratase, iron- sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, alpha subunit; PFAM: serine dehydratase alpha chain. (290 aa)
Taci_0269Carbamate kinase; KEGG: bcb:BCB4264_A0423 carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family. (318 aa)
Taci_0288KEGG: methylmalonyl-CoA mutase, large subunit; K01848 methylmalonyl-CoA mutase, N-terminal domain; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (559 aa)
Taci_0289PFAM: cobalamin B12-binding domain protein; KEGG: gsu:GSU1578 B12-binding protein. (140 aa)
Taci_0290TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: dol:Dole_0080 glyoxalase/bleomycin resistance protein/dioxygenase. (133 aa)
Taci_0301Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. (511 aa)
Taci_0302TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; KEGG: dds:Ddes_1528 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit. (282 aa)
Taci_0303TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: dde:Dde_1254 tartrate/fumarate subfamily Fe-S type hydro-lyase beta subunit. (185 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
Taci_0474KEGG: gsu:GSU0910 aldehyde:ferredoxin oxidoreductase, tungsten-containing; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (602 aa)
Taci_0485PFAM: Transketolase domain protein; KEGG: gsu:GSU2919 transketolase, N-terminal subunit. (277 aa)
Taci_0486PFAM: Transketolase domain protein; Transketolase central region; KEGG: pca:Pcar_2719 transketolase, C-terminal subunit. (313 aa)
Taci_0535PFAM: ROK family protein; KEGG: gbm:Gbem_1326 ROK family protein. (296 aa)
Taci_0585TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dvm:DvMF_2057 pyruvate ferredoxin/flavodoxin oxidoreductase. (185 aa)
Taci_0586PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sfu:Sfum_0300 thiamine pyrophosphate enzyme domain protein TPP-binding. (249 aa)
Taci_0587PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dal:Dalk_2231 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (353 aa)
Taci_0588PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: 4Fe-4S ferredoxin iron-sulfur binding domain protein; K00176 2-oxoglutarate ferredoxin oxidoreductase subunit delta. (76 aa)
Taci_0614PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: ppd:Ppro_0549 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. (579 aa)
Taci_0615TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit. (285 aa)
Taci_0794PFAM: phosphoglucose isomerase (PGI); KEGG: afw:Anae109_2086 glucose-6-phosphate isomerase. (441 aa)
Taci_0803KEGG: aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (731 aa)
Taci_0810Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bcy:Bcer98_0499 malate dehydrogenase. (414 aa)
fhsPFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rec:RHECIAT_CH0003236 formate- tetrahydrofolate ligase protein; Belongs to the formate--tetrahydrofolate ligase family. (554 aa)
Taci_0833TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; KEGG: bha:BH3163 pyruvate kinase; Belongs to the pyruvate kinase family. (582 aa)
Taci_0889KEGG: bha:BH3560 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (274 aa)
Taci_0964PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gur:Gura_2189 pyruvate ferredoxin/flavodoxin oxidoreductase. (185 aa)
Taci_0965PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gur:Gura_2190 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (271 aa)
Taci_0966PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pca:Pcar_1030 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (374 aa)
Taci_0967PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2714 4Fe-4S ferredoxin iron-sulfur binding domain protein. (69 aa)
Taci_1013Fructose-1,6-bisphosphatase, class II; KEGG: dvl:Dvul_1592 fructose 1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein. (328 aa)
Taci_1059KEGG: gsu:GSU0580 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; Belongs to the PEP-utilizing enzyme family. (882 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
Taci_1130PFAM: Transketolase central region; Transketolase domain protein; KEGG: sfu:Sfum_1302 transketolase. (648 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
Taci_1436TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sus:Acid_6996 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. (1175 aa)
Taci_1548PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: ppw:PputW619_3319 L-serine ammonia-lyase. (519 aa)
Taci_1664KEGG: bha:BH2502 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
Taci_1678PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; KEGG: sfu:Sfum_3264 phosphoenolpyruvate synthase. (588 aa)
Taci_1720PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcb:BCB4264_A2424 threonine ammonia-lyase, catabolic. (330 aa)
Taci_1733KEGG: bmn:BMA10247_1438 serine O-acetyltransferase. (215 aa)
Taci_1734TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pca:Pcar_2430 cysteine synthase A. (301 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (416 aa)
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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