STRINGSTRING
Afer_0541 Afer_0541 Afer_0598 Afer_0598 Afer_0599 Afer_0599 Afer_0766 Afer_0766 Afer_0767 Afer_0767 Afer_0768 Afer_0768 Afer_0769 Afer_0769 Afer_0956 Afer_0956 Afer_1234 Afer_1234 Afer_1236 Afer_1236 Afer_1237 Afer_1237 sepF sepF Afer_1239 Afer_1239 Afer_1240 Afer_1240 ftsZ ftsZ Afer_1242 Afer_1242 murB murB murC murC Afer_1245 Afer_1245 Afer_1246 Afer_1246 murD murD mraY mraY murE murE Afer_1250 Afer_1250 Afer_1251 Afer_1251 rsmH rsmH mraZ mraZ murA murA murE-2 murE-2 Afer_1886 Afer_1886
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Afer_0541KEGG: acr:Acry_1011 hypothetical protein. (391 aa)
Afer_0598PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: sru:SRU_2342 Mur ligase family protein. (526 aa)
Afer_0599D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (369 aa)
Afer_0766TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA; KEGG: fre:Franean1_5269 cell shape determining protein MreB. (342 aa)
Afer_0767Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (280 aa)
Afer_0768TIGRFAM: rod shape-determining protein MreD; KEGG: aoe:Clos_1763 hypothetical protein. (167 aa)
Afer_0769Penicillin-binding protein 2; KEGG: fre:Franean1_5266 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain. (644 aa)
Afer_0956TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: nca:Noca_3461 rod shape-determining protein RodA; Belongs to the SEDS family. (382 aa)
Afer_1234PFAM: Pirin domain protein; KEGG: ace:Acel_1948 pirin domain-containing protein; Belongs to the pirin family. (318 aa)
Afer_1236PFAM: DivIVA family protein; KEGG: nfa:nfa17740 hypothetical protein. (307 aa)
Afer_1237PFAM: protein of unknown function YGGT; KEGG: azc:AZC_3317 hypothetical protein. (89 aa)
sepFProtein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (179 aa)
Afer_1239PFAM: alanine racemase domain protein; KEGG: afw:Anae109_1365 alanine racemase domain- containing protein. (230 aa)
Afer_1240PFAM: protein of unknown function DUF152; KEGG: rxy:Rxyl_1488 protein of unknown function DUF152. (209 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (362 aa)
Afer_1242Hypothetical protein; KEGG: sen:SACE_5302 putative sugar transport integral membrane protein. (202 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (317 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (455 aa)
Afer_1245Undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; KEGG: pzu:PHZ_c2323 UDP-N-acetylglucosamine--N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase. (350 aa)
Afer_1246PFAM: cell cycle protein; KEGG: nfa:nfa17650 putative cell division protein; Belongs to the SEDS family. (379 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (437 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (344 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (499 aa)
Afer_1250Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ace:Acel_1004 peptidoglycan glycosyltransferase. (592 aa)
Afer_1251Hypothetical protein. (142 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (319 aa)
mraZPFAM: protein of unknown function UPF0040; KEGG: cth:Cthe_0982 MraZ protein; Belongs to the MraZ family. (140 aa)
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (423 aa)
murE-2UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (487 aa)
Afer_1886Actin-like ATPase involved in cell morphogenesis; KEGG: cbf:CLI_0218 mbl protein. (326 aa)
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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