STRINGSTRING
ACZ07034.1 ACZ07034.1 lpxD lpxD kdsA kdsA ACZ07480.1 ACZ07480.1 ACZ08479.1 ACZ08479.1 ACZ08669.1 ACZ08669.1 lpxK lpxK ACZ09202.1 ACZ09202.1 ACZ09203.1 ACZ09203.1 lpxA lpxA ACZ09205.1 ACZ09205.1 lpxC lpxC ACZ09211.1 ACZ09211.1 kdsB kdsB ACZ09522.1 ACZ09522.1 ACZ09574.1 ACZ09574.1 ACZ09578.1 ACZ09578.1 ACZ09579.1 ACZ09579.1 ACZ09580.1 ACZ09580.1 secF secF secD secD ACZ09584.1 ACZ09584.1 ACZ09586.1 ACZ09586.1 ACZ09587.1 ACZ09587.1 ACZ09745.1 ACZ09745.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACZ07034.1TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: abu:Abu_0978 HAD-superfamily phosphatase. (164 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N- acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (336 aa)
kdsAKEGG: pca:Pcar_1944 2-dehydro-3- deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. (281 aa)
ACZ07480.1PFAM: OstA family protein; KEGG: glo:Glov_1235 organic solvent tolerance protein. (1194 aa)
ACZ08479.1PFAM: protein of unknown function DUF374; KEGG: dal:Dalk_1795 protein of unknown function DUF374. (211 aa)
ACZ08669.1KpsF/GutQ family protein; KEGG: vco:VC0395_A2104 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; SMART: CBS domain containing protein; Belongs to the SIS family. GutQ/KpsF subfamily. (319 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (318 aa)
ACZ09202.1lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (358 aa)
ACZ09203.1PFAM: protein of unknown function DUF1009; KEGG: dat:HRM2_22450 hypothetical protein. (268 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
ACZ09205.1acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (278 aa)
ACZ09211.1PFAM: lipid A biosynthesis acyltransferase; KEGG: sat:SYN_00133 lipid A biosynthesis lauroyl acyltransferase. (284 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
ACZ09522.1Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (397 aa)
ACZ09574.1Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (285 aa)
ACZ09578.1PFAM: permease YjgP/YjgQ family protein; KEGG: gme:Gmet_1248 permease YjgP/YjgQ. (360 aa)
ACZ09579.1PFAM: permease YjgP/YjgQ family protein; KEGG: glo:Glov_2589 permease YjgP/YjgQ family protein. (364 aa)
ACZ09580.1PFAM: Colicin V production protein; KEGG: rfe:RF_0045 hypothetical protein. (196 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (308 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (406 aa)
ACZ09584.1Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (137 aa)
ACZ09586.1PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: apa:APP7_0341 putative ABC transporter ATP- binding protein. (245 aa)
ACZ09587.1PFAM: OstA family protein; KEGG: conserved hypothetical protein. (742 aa)
ACZ09745.1PFAM: lipid A biosynthesis acyltransferase; KEGG: cps:CPS_2773 putative lipid A biosynthesis acyltransferase. (284 aa)
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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