STRINGSTRING
ACZ07054.1 ACZ07054.1 ACZ07055.1 ACZ07055.1 ACZ07612.1 ACZ07612.1 ACZ09023.1 ACZ09023.1 ACZ09024.1 ACZ09024.1 metAA metAA hisC hisC ACZ09092.1 ACZ09092.1 ACZ09122.1 ACZ09122.1 aroK aroK aroE aroE ACZ09228.1 ACZ09228.1 aroC aroC aroA aroA aroB aroB ACZ09279.1 ACZ09279.1 ACZ09280.1 ACZ09280.1 thrB thrB ACZ09806.1 ACZ09806.1 ACZ09812.1 ACZ09812.1 ACZ09857.1 ACZ09857.1 ACZ09863.1 ACZ09863.1 ACZ09905.1 ACZ09905.1 ACZ09923.1 ACZ09923.1 ACZ10121.1 ACZ10121.1 ACZ10140.1 ACZ10140.1 ACZ10141.1 ACZ10141.1 trpD trpD ACZ10143.1 ACZ10143.1 trpF trpF trpB trpB trpA trpA pepA pepA ACZ10233.1 ACZ10233.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACZ07054.1TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: hac:Hac_0304 hypothetical protein. (175 aa)
ACZ07055.1TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gme:Gmet_2988 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa)
ACZ07612.1Branched-chain-amino-acid transaminase; PFAM: aminotransferase class IV; KEGG: dar:Daro_3294 branched-chain amino acid aminotransferase. (312 aa)
ACZ09023.1O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: sat:SYN_01255 O-acetyl-L-homoserine sulfhydrolase / O-acetyl-L-serine sulfhydrolase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. (423 aa)
ACZ09024.1KEGG: cju:C8J_1146 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (292 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (289 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmw:Mmwyl1_1133 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa)
ACZ09092.1PFAM: aminotransferase class I and II; KEGG: ftn:FTN_0410 aspartate aminotransferase. (396 aa)
ACZ09122.1KEGG: nis:NIS_1040 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (497 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa)
aroEShikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa)
ACZ09228.1Chorismate mutase; KEGG: vsp:VS_0556 P-protein [includes: chorismate mutase,Prephenatedehydratase]; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase. (378 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (354 aa)
ACZ09279.1PFAM: Prephenate dehydrogenase; KEGG: maq:Maqu_1025 3-phosphoshikimate 1- carboxyvinyltransferase. (282 aa)
ACZ09280.1Phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: gme:Gmet_0346 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. (340 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (300 aa)
ACZ09806.1KEGG: vvu:VV1_0333 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20. (487 aa)
ACZ09812.1PFAM: aminotransferase class I and II; KEGG: ypg:YpAngola_A2760 aminotransferase, classes I and II. (386 aa)
ACZ09857.1PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: glo:Glov_1214 homoserine dehydrogenase. (398 aa)
ACZ09863.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: bxe:Bxe_B2346 putative dehydrogenase. (313 aa)
ACZ09905.1TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gur:Gura_3907 cysteine synthase A. (304 aa)
ACZ09923.1PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12- binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: gsu:GSU2921 5-methyltetrahydrofolate- homocysteine methyltransferase, truncation. (791 aa)
ACZ10121.1TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gme:Gmet_2988 cysteine synthase. (302 aa)
ACZ10140.1Anthranilate synthase; PFAM: Chorismate binding-like; KEGG: ccv:CCV52592_1683 anthranilate synthase component 1 (anthranilate synthasecomponent I). (419 aa)
ACZ10141.1TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cff:CFF8240_0351 anthranilate synthase component II. (197 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)
ACZ10143.1PFAM: Indole-3-glycerol phosphate synthase; KEGG: abu:Abu_0850 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (244 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cco:CCC13826_0970 N- (5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (196 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (252 aa)
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (471 aa)
ACZ10233.1Serine acetyltransferase-like protein; KEGG: cjd:JJD26997_1249 serine acetyltransferase. (180 aa)
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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