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| | ACZ06995.1 | TIGRFAM: homoaconitate hydratase family protein; 3- isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein; KEGG: 3-isopropylmalate dehydratase; K01703 3- isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Belongs to the aconitase/IPM isomerase family. (435 aa) |
| | ACZ06998.1 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: 3-isopropylmalate dehydratase small subunit; K01704 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Belongs to the LeuD family. (181 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (359 aa) |
| | ACZ07054.1 | TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: hac:Hac_0304 hypothetical protein. (175 aa) |
| | ACZ07055.1 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gme:Gmet_2988 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa) |
| | ACZ07141.1 | Hypothetical protein; KEGG: ATP-dependent RNA helicase; K01509 adenosinetriphosphatase. (212 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (131 aa) |
| | ACZ07183.1 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa) |
| | ACZ07258.1 | KEGG: ASNS; asparagine synthetase; K01953 asparagine synthase (glutamine-hydrolysing); TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (528 aa) |
| | kdsA | KEGG: pca:Pcar_1944 2-dehydro-3- deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. (281 aa) |
| | ACZ07282.1 | KEGG: scl:sce1139 hypothetical protein. (306 aa) |
| | ACZ07336.1 | KEGG: scl:sce1139 hypothetical protein. (306 aa) |
| | ACZ07360.1 | Sulfite reductase (ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: wsu:WS1004 hypothetical protein. (490 aa) |
| | ACZ07374.1 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pha:PSHAb0463 acetolactate synthase 3 regulatory subunit. (162 aa) |
| | ACZ07473.1 | PFAM: aldo/keto reductase; KEGG: prostaglandin f synthase; K00120. (267 aa) |
| | ACZ07517.1 | Phosphoserine phosphatase-like protein; KEGG: ilo:IL2596 phosphoserine phosphatase. (217 aa) |
| | ACZ07526.1 | PFAM: Cupin 2 conserved barrel domain protein; KEGG: rhi:NGR_c06260 hypothetical protein. (305 aa) |
| | ACZ07541.1 | TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_0935 2-deoxy-D-gluconate 3- dehydrogenase. (259 aa) |
| | ACZ07931.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: asa:ASA_3580 sorbitol-6-phosphate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa) |
| | ACZ06905.1 | Amidohydrolase; KEGG: cjd:JJD26997_1065 carboxypeptidase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (394 aa) |
| | ACZ07968.1 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: dps:DP2376 biotin synthase. (364 aa) |
| | ACZ08036.1 | PFAM: HAD-superfamily hydrolase subfamily IB hypothetical 1; KEGG: hypothetical protein. (215 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | ACZ08047.1 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa) |
| | ACZ08168.1 | TIGRFAM: C_GCAxxG_C_C family protein; KEGG: geo:Geob_0479 C_GCAxxG_C_C family protein. (153 aa) |
| | ACZ08173.1 | TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: amc:MADE_01969 alcohol dehydrogenase, zinc- containing. (333 aa) |
| | ACZ08228.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: gsu:GSU0696 glucose 1-dehydrogenase. (254 aa) |
| | ACZ08232.1 | KEGG: mxa:MXAN_6509 acid phosphatase. (325 aa) |
| | ACZ08443.1 | TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: geo:Geob_0520 HAD-superfamily subfamily IB hydrolase, TIGR01490. (242 aa) |
| | asnA | KEGG: aspartate--ammonia ligase; K01914 aspartate--ammonia ligase; TIGRFAM: aspartate/ammonia ligase; PFAM: aspartate--ammonia ligase. (336 aa) |
| | ACZ08469.1 | Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (155 aa) |
| | ACZ08501.1 | KEGG: mxa:MXAN_2889 radical SAM domain-containing protein. (283 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (342 aa) |
| | ACZ08520.1 | TIGRFAM: diaminopropionate ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: dps:DP1388 diaminopropionate ammonia-lyase. (405 aa) |
| | aroE | Shikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa) |
| | ACZ09228.1 | Chorismate mutase; KEGG: vsp:VS_0556 P-protein [includes: chorismate mutase,Prephenatedehydratase]; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase. (378 aa) |
| | ACZ09245.1 | PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: eum:ECUMN_3432 hypothetical protein. (391 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (354 aa) |
| | ACZ09279.1 | PFAM: Prephenate dehydrogenase; KEGG: maq:Maqu_1025 3-phosphoshikimate 1- carboxyvinyltransferase. (282 aa) |
| | ACZ09280.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: gme:Gmet_0346 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. (340 aa) |
| | ACZ09314.1 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (411 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (73 aa) |
| | ACZ09317.1 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: pca:Pcar_1437 malonyl CoA-acyl carrier protein transacylase. (301 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (326 aa) |
| | ACZ09386.1 | KEGG: Protein kinase domain containing protein. (317 aa) |
| | ACZ09416.1 | PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce4853 hypothetical protein. (333 aa) |
| | ACZ09464.1 | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (232 aa) |
| | ACZ09467.1 | FolC bifunctional protein; KEGG: rco:RC0779 folylpolyglutamate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein. (413 aa) |
| | ACZ09489.1 | PFAM: beta-lactamase domain protein; KEGG: gur:Gura_2063 beta-lactamase domain- containing protein. (256 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; protein of unknown function DUF201; KEGG: dat:HRM2_47760 CarB2; Belongs to the CarB family. (1069 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (351 aa) |
| | ACZ09530.1 | PFAM: AroM family protein; KEGG: eta:ETA_25570 protein of aro operon, regulated by AroR. (227 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (300 aa) |
| | ACZ09581.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (356 aa) |
| | fabV | Trans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa) |
| | ACZ09607.1 | Amidohydrolase; KEGG: dac:Daci_1417 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (395 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa) |
| | ACZ09634.1 | KEGG: sek:SSPA3744 hypothetical protein; Belongs to the HisA/HisF family. (283 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa) |
| | ACZ09819.1 | Tetrahydrodipicolinate succinyltransferase domain protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (231 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (241 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (332 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (285 aa) |
| | ACZ09833.1 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: hhe:HH0618 aspartate kinase; Belongs to the aspartokinase family. (400 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (435 aa) |
| | ACZ09856.1 | KEGG: sfu:Sfum_2173 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (406 aa) |
| | ACZ09857.1 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: glo:Glov_1214 homoserine dehydrogenase. (398 aa) |
| | ACZ09876.1 | PFAM: aspartate/glutamate/uridylate kinase; KEGG: vok:COSY_0382 glutamate 5-kinase. (248 aa) |
| | ACZ09905.1 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gur:Gura_3907 cysteine synthase A. (304 aa) |
| | ACZ09922.1 | PFAM: Vitamin B12 dependent methionine synthase activation region; KEGG: dal:Dalk_4198 vitamin B12 dependent methionine synthase activation region. (225 aa) |
| | ACZ09923.1 | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12- binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: gsu:GSU2921 5-methyltetrahydrofolate- homocysteine methyltransferase, truncation. (791 aa) |
| | ACZ09936.1 | Nucleotide sugar dehydrogenase; KEGG: sfu:Sfum_3370 UDP-glucose/GDP-mannose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (440 aa) |
| | ACZ09954.1 | PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; KEGG: lpp:lpp1601 3-oxoacyl-(acyl carrier protein) synthase III. (325 aa) |
| | ACZ10045.1 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpe:KPK_5267 sorbitol-6-phosphate 2- dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (267 aa) |
| | ACZ10121.1 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gme:Gmet_2988 cysteine synthase. (302 aa) |
| | ACZ10141.1 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cff:CFF8240_0351 anthranilate synthase component II. (197 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | ACZ10143.1 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: abu:Abu_0850 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (244 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cco:CCC13826_0970 N- (5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (196 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (252 aa) |
| | ACZ10180.1 | KEGG: aci:ACIAD1456 hypothetical protein. (424 aa) |
| | ACZ10233.1 | Serine acetyltransferase-like protein; KEGG: cjd:JJD26997_1249 serine acetyltransferase. (180 aa) |
| | ACZ10279.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: oca:OCAR_5704 oxidoreductase, short chain dehydrogenase/reductase family. (264 aa) |
| | ACZ10280.1 | PFAM: aldo/keto reductase; KEGG: prostaglandin f2-alpha synthase. (280 aa) |
| | ACZ10286.1 | KEGG: pla:Plav_1142 putrescine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region. (338 aa) |
| | ACZ10326.1 | PFAM: MaoC domain protein dehydratase; KEGG: oan:Oant_0316 MaoC domain protein dehydratase. (147 aa) |
| | ACZ10328.1 | KEGG: reu:Reut_A2824 NapD-like protein. (320 aa) |
| | ACZ10335.1 | PFAM: aldo/keto reductase; KEGG: asu:Asuc_1306 aldo/keto reductase. (374 aa) |
| | ACZ10368.1 | TIGRFAM: amidohydrolase; PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: eca:ECA2964 putative peptidase; Belongs to the peptidase M20A family. (398 aa) |
| | ACZ10457.1 | Amidohydrolase; KEGG: swd:Swoo_0259 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (399 aa) |
| | ACZ10459.1 | TIGRFAM: acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hypothetical protein. (417 aa) |
| | ACZ10470.1 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: shl:Shal_2747 short-chain dehydrogenase/reductase SDR. (236 aa) |
| | ACZ10612.1 | KEGG: dal:Dalk_2955 histidinol phosphate phosphatase HisJ family; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa) |
| | ACZ10643.1 | PFAM: aldo/keto reductase; KEGG: gur:Gura_4373 2,5-didehydrogluconate reductase. (283 aa) |
| | ACZ10909.1 | KEGG: hch:HCH_05422 dihydrofolate reductase. (172 aa) |
| | ACZ08521.1 | TIGRFAM: M20/DapE family protein YgeY; PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: shl:Shal_0637 peptidase. (436 aa) |
| | ACZ08522.1 | TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: ecl:EcolC_0838 carbamoyltransferase YgeW; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (401 aa) |
| | ACZ08547.1 | Amidohydrolase; KEGG: aminoacylase; K01436 aminoacylase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (385 aa) |
| | ACZ08565.1 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: pag:PLES_15431 putative dihydrofolate reductase. (188 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa) |
| | ACZ08606.1 | Hypothetical protein; KEGG: bav:BAV2997 biotin carboxyl carrier protein of acetyl-CoA carboxylase. (131 aa) |
| | ACZ08662.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (367 aa) |
| | ACZ08739.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (274 aa) |
| | ACZ08737.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (276 aa) |
| | ACZ08740.1 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: dat:HRM2_17030 FolC; Belongs to the folylpolyglutamate synthase family. (407 aa) |
| | ACZ08751.1 | Purine or other phosphorylase family 1; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (249 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (291 aa) |
| | argD | KEGG: sat:SYN_02155 acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (387 aa) |
| | ACZ08765.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (331 aa) |
| | ACZ08843.1 | Amidohydrolase; KEGG: nis:NIS_1768 N-acetyl-L-amino acid amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (399 aa) |
| | ACZ08846.1 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpe:KPK_5267 sorbitol-6-phosphate 2- dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (267 aa) |
| | ACZ08864.1 | PFAM: protein of unknown function DUF479; KEGG: apa:APP7_1254 hypothetical protein. (196 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa) |
| | ACZ08892.1 | Metal-dependent amidase/aminoacylase/carboxypeptidase-like protein; KEGG: hypothetical LOC584527. (419 aa) |
| | ACZ09008.1 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: aha:AHA_1152 isocitrate dehydrogenase. (333 aa) |
| | ACZ09022.1 | Amidase, hydantoinase/carbamoylase family; KEGG: hiq:CGSHiGG_06340 allantoate amidohydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20. (394 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (289 aa) |
| | ACZ09027.1 | PFAM: tRNA synthetase class II (G H P and S); KEGG: gbm:Gbem_0553 histidyl-tRNA synthetase. (375 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (205 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmw:Mmwyl1_1133 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: azc:AZC_4502 imidazoleglycerol-phosphate dehydratase. (196 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa) |
| | hisA | KEGG: cco:CCC13826_0444 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. (237 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | ACZ09122.1 | KEGG: nis:NIS_1040 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (497 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pca:Pcar_2418 argininosuccinate lyase. (461 aa) |
| | argG | KEGG: argininosuccinate synthase; K01940 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa) |
| | ACZ09222.1 | PFAM: aldo/keto reductase; KEGG: kpn:KPN_01195 putative an aldehyde reductase. (294 aa) |
| | ACZ06920.1 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ecl:EcolC_1649 short-chain dehydrogenase/reductase SDR. (252 aa) |
| | ilvD | KEGG: sat:SYN_01708 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (552 aa) |
| | ACZ06988.1 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ade:Adeh_3448 L-threonine ammonia-lyase. (401 aa) |
| | ACZ06989.1 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sfu:Sfum_3025 acetolactate synthase, small subunit. (161 aa) |
| | ACZ06991.1 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: dds:Ddes_1904 acetolactate synthase, small subunit. (162 aa) |
