STRINGSTRING
mutL mutL ACZ08775.1 ACZ08775.1 uvrA uvrA ACZ08460.1 ACZ08460.1 clpB clpB ACZ08116.1 ACZ08116.1 ruvA ruvA mutS2 mutS2 ACZ10417.1 ACZ10417.1 ACZ10412.1 ACZ10412.1 recG recG ACZ10348.1 ACZ10348.1 ACZ10200.1 ACZ10200.1 ychF ychF ftsH ftsH ACZ09447.1 ACZ09447.1 ACZ09419.1 ACZ09419.1 ACZ09408.1 ACZ09408.1 ACZ09407.1 ACZ09407.1 ACZ09382.1 ACZ09382.1 ACZ09367.1 ACZ09367.1 ACZ09208.1 ACZ09208.1 clpX clpX uvrB uvrB ACZ07775.1 ACZ07775.1 ACZ07579.1 ACZ07579.1 ACZ07073.1 ACZ07073.1 ruvB ruvB lon lon smc smc ACZ08862.1 ACZ08862.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (621 aa)
ACZ08775.1TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sat:SYN_01009 calcium-transporting ATPase. (883 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa)
ACZ08460.1KEGG: Ca2+-ATPase; TIGRFAM: calcium-translocating P-type ATPase, PMCA- type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase. (875 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa)
ACZ08116.1PFAM: DnaB domain protein helicase domain protein; KEGG: abu:Abu_0658 replicative DNA helicase. (430 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (780 aa)
ACZ10417.1KEGG: cff:CFF8240_0385 hypothetical protein. (853 aa)
ACZ10412.1PFAM: UvrD/REP helicase; KEGG: cff:CFF8240_0386 ATP-dependent DNA helicase UvrD. (995 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (688 aa)
ACZ10348.1PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bam:Bamb_1999 ABC transporter related. (752 aa)
ACZ10200.1Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (265 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (682 aa)
ACZ09447.1KEGG: abu:Abu_0110 hypothetical protein. (619 aa)
ACZ09419.1TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: ypb:YPTS_2489 magnesium-translocating P-type ATPase. (908 aa)
ACZ09408.1PFAM: Heavy metal transport/detoxification protein; KEGG: abu:Abu_1859 heavy metal-(Cd/Co/Hg/Pb/Zn)- translocating P-type ATPase. (72 aa)
ACZ09407.1TIGRFAM: cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: wsu:WS1121 heavy metal-transporting ATPase. (629 aa)
ACZ09382.1PFAM: DnaB domain protein helicase domain protein; KEGG: dvl:Dvul_2027 replicative DNA helicase. (369 aa)
ACZ09367.1PFAM: terminase GpA; KEGG: spe:Spro_4922 terminase GpA. (604 aa)
ACZ09208.1PFAM: UvrD/REP helicase; KEGG: bba:Bd3339 ATP-dependent DNA helicase. (724 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (408 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (657 aa)
ACZ07775.1TIGRFAM: calcium-translocating P-type ATPase, PMCA- type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: glo:Glov_1814 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (898 aa)
ACZ07579.1TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: kpe:KPK_3276 magnesium-translocating P-type ATPase. (878 aa)
ACZ07073.1TIGRFAM: calcium-translocating P-type ATPase, PMCA- type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sat:SYN_01009 calcium-transporting ATPase. (898 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (339 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (769 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1175 aa)
ACZ08862.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (458 aa)
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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