STRINGSTRING
ACZ07884.1 ACZ07884.1 ACZ06973.1 ACZ06973.1 ACZ07179.1 ACZ07179.1 ACZ07461.1 ACZ07461.1 ACZ07634.1 ACZ07634.1 cobS cobS ACZ07870.1 ACZ07870.1 cbiM cbiM cbiN cbiN cbiA cbiA ACZ07876.1 ACZ07876.1 cbiD cbiD ACZ07878.1 ACZ07878.1 ACZ07879.1 ACZ07879.1 ACZ07880.1 ACZ07880.1 ACZ07881.1 ACZ07881.1 ACZ07882.1 ACZ07882.1 ACZ07883.1 ACZ07883.1 ACZ07891.1 ACZ07891.1 hemL hemL ACZ07893.1 ACZ07893.1 ACZ07895.1 ACZ07895.1 ACZ07896.1 ACZ07896.1 ACZ07904.1 ACZ07904.1 ACZ07913.1 ACZ07913.1 ACZ08222.1 ACZ08222.1 ACZ08500.1 ACZ08500.1 purC purC ACZ09154.1 ACZ09154.1 ACZ09843.1 ACZ09843.1 ACZ10160.1 ACZ10160.1 ACZ10330.1 ACZ10330.1 ACZ10917.1 ACZ10917.1 cobQ cobQ cobD cobD hemA hemA hemC hemC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACZ07884.1Adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; KEGG: yen:YE2710 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase. (184 aa)
ACZ06973.1Hypothetical protein. (237 aa)
ACZ07179.1PFAM: protein of unknown function DUF336; KEGG: azc:AZC_3294 hypothetical protein. (157 aa)
ACZ07461.1Coproporphyrinogen dehydrogenase; KEGG: ccv:CCV52592_0647 quinone-reactive Ni/Fe hydrogenase, large subunit; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (415 aa)
ACZ07634.1PFAM: von Willebrand factor type A; KEGG: ccv:CCV52592_1750 von Willebrand factor type A domain-containing protein. (233 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (242 aa)
ACZ07870.1PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ppd:Ppro_1268 cobalamin (vitamin B12) biosynthesis CbiX protein. (122 aa)
cbiMCobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (236 aa)
cbiNCobalt transport protein CbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (95 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (442 aa)
ACZ07876.1PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: gbm:Gbem_3545 precorrin-8X methylmutase CbiC/CobH. (211 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (365 aa)
ACZ07878.1TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: yen:YE2721 cobalt-precorrin-6Y C(5)- methyltransferase. (207 aa)
ACZ07879.1TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: methyltransferase small; KEGG: geo:Geob_0032 precorrin-6y C5,15- methyltransferase (decarboxylating), CbiE subunit. (187 aa)
ACZ07880.1TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: dat:HRM2_02310 CbiL; Belongs to the precorrin methyltransferase family. (238 aa)
ACZ07881.1KEGG: tau:Tola_1675 precorrin-4 C11- methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (253 aa)
ACZ07882.1PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: tau:Tola_1674 cobalamin (vitamin B12) biosynthesis CbiG protein. (332 aa)
ACZ07883.1TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gme:Gmet_0485 cobyric acid synthase CobQ:precorrin-3B C17-methyltransferase region. (240 aa)
ACZ07891.1TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dat:HRM2_35960 HemD. (493 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gur:Gura_4245 glutamate-1-semialdehyde aminotransferase. (434 aa)
ACZ07893.1Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (343 aa)
ACZ07895.1Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: ppd:Ppro_0442 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (325 aa)
ACZ07896.1TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: kpe:KPK_0925 precorrin-6x reductase. (250 aa)
ACZ07904.1PFAM: protein of unknown function DUF336; KEGG: tau:Tola_1696 ATP/cobalamin adenosyltransferase. (159 aa)
ACZ07913.1PFAM: cobalamin adenosyltransferase; KEGG: maq:Maqu_1230 cobalamin adenosyltransferase. (248 aa)
ACZ08222.1KEGG: dal:Dalk_3341 hypothetical protein. (351 aa)
ACZ08500.1KEGG: mxa:MXAN_2888 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB. (443 aa)
purCKEGG: dno:DNO_1112 phosphoribosylaminoimidazole- succinocarboxamidesynthase; TIGRFAM: phosphoribosylaminoimidazole- succinocarboxamide synthase; PFAM: SAICAR synthetase. (235 aa)
ACZ09154.1KEGG: dol:Dole_3236 siroheme synthase. (145 aa)
ACZ09843.1KEGG: bpy:Bphyt_5572 hypothetical protein. (143 aa)
ACZ10160.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (357 aa)
ACZ10330.1Hypothetical protein; KEGG: bba:Bd2899 protoporphyrinogen oxidase. (176 aa)
ACZ10917.1Coproporphyrinogen dehydrogenase; KEGG: bas:BUsg532 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (468 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (494 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (308 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (335 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (297 aa)
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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