STRINGSTRING
ACZ09043.1 ACZ09043.1 trpS trpS ACZ09975.1 ACZ09975.1 gltX gltX ACZ10337.1 ACZ10337.1 argS argS cysS cysS tyrS tyrS ileS ileS ACZ07258.1 ACZ07258.1 nadE nadE ACZ06897.1 ACZ06897.1 ACZ09011.1 ACZ09011.1 ACZ08995.1 ACZ08995.1 nadD nadD ACZ08880.1 ACZ08880.1 ACZ08556.1 ACZ08556.1 valS valS metG metG mnmA-2 mnmA-2 guaA guaA ACZ08205.1 ACZ08205.1 ACZ07769.1 ACZ07769.1 mnmA mnmA leuS leuS thiI thiI ACZ07508.1 ACZ07508.1 ACZ07489.1 ACZ07489.1 argG argG coaD coaD tilS tilS tmcAL tmcAL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACZ09043.1TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: gsu:GSU1487 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (314 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (324 aa)
ACZ09975.1TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: yen:YE0580 nicotinamide-nucleotide adenylyltransferase. (344 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (504 aa)
ACZ10337.1PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: sat:SYN_00402 deoxyribodipyrimidine photolyase. (453 aa)
argSKEGG: hiq:CGSHiGG_10215 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (571 aa)
cysSKEGG: geo:Geob_0551 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (404 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (926 aa)
ACZ07258.1KEGG: ASNS; asparagine synthetase; K01953 asparagine synthase (glutamine-hydrolysing); TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (528 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (261 aa)
ACZ06897.1Hypothetical protein. (251 aa)
ACZ09011.1PFAM: protein of unknown function DUF218; KEGG: prw:PsycPRwf_1021 hypothetical protein. (243 aa)
ACZ08995.1PFAM: protein of unknown function DUF218; KEGG: vpa:VPA1680 hypothetical protein. (346 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (187 aa)
ACZ08880.1PFAM: protein of unknown function DUF218; KEGG: vsa:VSAL_I1272 vancomycin resistance protein SanA. (216 aa)
ACZ08556.1PFAM: PP-loop domain protein; KEGG: gme:Gmet_3336 PP-loop protein; Belongs to the TtcA family. (284 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. (638 aa)
mnmA-2tRNA (5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (512 aa)
ACZ08205.1PFAM: protein of unknown function DUF218; KEGG: set:SEN0100 probable secreted protein. (208 aa)
ACZ07769.1PFAM: protein of unknown function DUF218; KEGG: eck:EC55989_1545 hypothetical protein. (266 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (353 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: ppd:Ppro_1731 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (865 aa)
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (388 aa)
ACZ07508.1PFAM: PP-loop domain protein; KEGG: gsu:GSU0127 hypothetical protein; Belongs to the TtcA family. (276 aa)
ACZ07489.1rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (163 aa)
argGKEGG: argininosuccinate synthase; K01940 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (442 aa)
tmcALProtein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (383 aa)
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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