STRINGSTRING
ACZ06914.1 ACZ06914.1 ACZ06915.1 ACZ06915.1 ACZ06920.1 ACZ06920.1 dxr dxr ACZ06939.1 ACZ06939.1 ACZ06940.1 ACZ06940.1 ispE ispE ilvD ilvD ACZ06988.1 ACZ06988.1 ACZ06989.1 ACZ06989.1 ACZ06990.1 ACZ06990.1 ACZ06991.1 ACZ06991.1 leuA leuA ACZ06993.1 ACZ06993.1 ACZ06995.1 ACZ06995.1 ACZ06998.1 ACZ06998.1 leuB leuB ACZ07000.1 ACZ07000.1 ilvC ilvC ACZ07054.1 ACZ07054.1 ACZ07055.1 ACZ07055.1 dxs dxs pgk pgk ACZ07115.1 ACZ07115.1 ispF ispF ACZ07119.1 ACZ07119.1 ACZ07142.1 ACZ07142.1 ACZ07190.1 ACZ07190.1 ACZ07204.1 ACZ07204.1 ACZ07233.1 ACZ07233.1 ACZ07258.1 ACZ07258.1 ACZ07277.1 ACZ07277.1 ACZ07373.1 ACZ07373.1 ACZ07374.1 ACZ07374.1 ACZ07379.1 ACZ07379.1 ACZ07450.1 ACZ07450.1 gpmA gpmA prs prs ACZ07524.1 ACZ07524.1 ACZ07529.1 ACZ07529.1 ispG ispG ACZ07612.1 ACZ07612.1 ACZ07640.1 ACZ07640.1 ACZ07665.1 ACZ07665.1 hemA hemA hemC hemC ACZ07891.1 ACZ07891.1 hemL hemL ACZ07895.1 ACZ07895.1 ACZ07971.1 ACZ07971.1 tpiA tpiA gpmI gpmI ACZ08047.1 ACZ08047.1 ndk ndk ACZ08329.1 ACZ08329.1 ACZ08330.1 ACZ08330.1 ACZ08377.1 ACZ08377.1 ACZ08406.1 ACZ08406.1 guaB guaB asnA asnA ACZ08486.1 ACZ08486.1 ACZ08500.1 ACZ08500.1 ACZ08504.1 ACZ08504.1 ACZ08508.1 ACZ08508.1 ACZ08567.1 ACZ08567.1 accD accD accA accA pfkA pfkA ACZ08574.1 ACZ08574.1 metK metK ACZ08607.1 ACZ08607.1 ACZ08641.1 ACZ08641.1 ACZ08651.1 ACZ08651.1 ACZ08663.1 ACZ08663.1 ACZ08664.1 ACZ08664.1 ACZ08711.1 ACZ08711.1 ACZ08725.1 ACZ08725.1 argC argC argJ argJ argB argB argD argD ACZ08765.1 ACZ08765.1 ACZ08801.1 ACZ08801.1 ACZ08803.1 ACZ08803.1 ACZ08804.1 ACZ08804.1 ACZ08810.1 ACZ08810.1 ACZ08811.1 ACZ08811.1 ACZ08820.1 ACZ08820.1 ACZ08824.1 ACZ08824.1 ACZ08838.1 ACZ08838.1 plsY plsY gpsA gpsA fbp fbp ACZ08888.1 ACZ08888.1 ACZ08898.1 ACZ08898.1 ACZ08901.1 ACZ08901.1 ACZ08925.1 ACZ08925.1 ACZ08960.1 ACZ08960.1 purE purE purC purC purF purF purM purM purN purN purH purH purD purD glgC glgC glgA glgA ACZ09002.1 ACZ09002.1 ACZ09004.1 ACZ09004.1 ACZ09007.1 ACZ09007.1 ACZ09008.1 ACZ09008.1 ACZ09009.1 ACZ09009.1 metAA metAA ACZ09027.1 ACZ09027.1 hisG hisG hisD hisD hisC hisC hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI ACZ09036.1 ACZ09036.1 ACZ09043.1 ACZ09043.1 ACZ09063.1 ACZ09063.1 ACZ09092.1 ACZ09092.1 ACZ09122.1 ACZ09122.1 argH argH argG argG ACZ09154.1 ACZ09154.1 glyA glyA ACZ09193.1 ACZ09193.1 ACZ09194.1 ACZ09194.1 aroQ aroQ aroK aroK aroE aroE ACZ09228.1 ACZ09228.1 ACZ09239.1 ACZ09239.1 miaA miaA ACZ09253.1 ACZ09253.1 ACZ09254.1 ACZ09254.1 ACZ09255.1 ACZ09255.1 ACZ09256.1 ACZ09256.1 ACZ09264.1 ACZ09264.1 aroC aroC aroA aroA aroB aroB ACZ09279.1 ACZ09279.1 ACZ09280.1 ACZ09280.1 ACZ09292.1 ACZ09292.1 acpP acpP ACZ09317.1 ACZ09317.1 ldh ldh surE surE thrB thrB ACZ09544.1 ACZ09544.1 fabV fabV ACZ09594.1 ACZ09594.1 ACZ09595.1 ACZ09595.1 xpt xpt ACZ09622.1 ACZ09622.1 ribBA ribBA ACZ09624.1 ACZ09624.1 ACZ09625.1 ACZ09625.1 ribH ribH proC proC proA proA proB proB ACZ09652.1 ACZ09652.1 ACZ09655.1 ACZ09655.1 ACZ09800.1 ACZ09800.1 ACZ09812.1 ACZ09812.1 ACZ09814.1 ACZ09814.1 ACZ09819.1 ACZ09819.1 dapB dapB asd asd dapA dapA dapF dapF ACZ09833.1 ACZ09833.1 lysA lysA ACZ09847.1 ACZ09847.1 ACZ09853.1 ACZ09853.1 ACZ09856.1 ACZ09856.1 ACZ09857.1 ACZ09857.1 ACZ09876.1 ACZ09876.1 ACZ09892.1 ACZ09892.1 ACZ09903.1 ACZ09903.1 ACZ09905.1 ACZ09905.1 ACZ09914.1 ACZ09914.1 ACZ09923.1 ACZ09923.1 ACZ09959.1 ACZ09959.1 ACZ10066.1 ACZ10066.1 ACZ10090.1 ACZ10090.1 ACZ10121.1 ACZ10121.1 ACZ10140.1 ACZ10140.1 ACZ10141.1 ACZ10141.1 trpD trpD ACZ10143.1 ACZ10143.1 trpF trpF trpB trpB trpA trpA ACZ10150.1 ACZ10150.1 ACZ10160.1 ACZ10160.1 ACZ10161.1 ACZ10161.1 gltX gltX ACZ10203.1 ACZ10203.1 ACZ10204.1 ACZ10204.1 ACZ10233.1 ACZ10233.1 ACZ10270.1 ACZ10270.1 ACZ10279.1 ACZ10279.1 ACZ10385.1 ACZ10385.1 ACZ10436.1 ACZ10436.1 ACZ10449.1 ACZ10449.1 ACZ10459.1 ACZ10459.1 ACZ10470.1 ACZ10470.1 ACZ10472.1 ACZ10472.1 ACZ10473.1 ACZ10473.1 ispD ispD ACZ10492.1 ACZ10492.1 ACZ10599.1 ACZ10599.1 ACZ10612.1 ACZ10612.1 ACZ10615.1 ACZ10615.1 ACZ10671.1 ACZ10671.1 adk adk ACZ10840.1 ACZ10840.1 ACZ10846.1 ACZ10846.1 ACZ10851.1 ACZ10851.1 eno eno ACZ10917.1 ACZ10917.1 ispH ispH ACZ10958.1 ACZ10958.1 ACZ10960.1 ACZ10960.1 pgi pgi
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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ACZ06914.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; biotin/lipoyl attachment domain-containing protein; KEGG: pla:Plav_3138 dihydrolipoamide dehydrogenase. (563 aa)
ACZ06915.1PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: dat:HRM2_47640 PdhC. (442 aa)
ACZ06920.1PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ecl:EcolC_1649 short-chain dehydrogenase/reductase SDR. (252 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (382 aa)
ACZ06939.1PFAM: phosphatidate cytidylyltransferase; KEGG: pca:Pcar_1916 putative phosphatidate cytidylyltransferase. (306 aa)
ACZ06940.1Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (231 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (285 aa)
ilvDKEGG: sat:SYN_01708 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (552 aa)
ACZ06988.1TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ade:Adeh_3448 L-threonine ammonia-lyase. (401 aa)
ACZ06989.1TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sfu:Sfum_3025 acetolactate synthase, small subunit. (161 aa)
ACZ06990.1TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: geo:Geob_1509 acetolactate synthase, large subunit, biosynthetic type. (568 aa)
ACZ06991.1TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: dds:Ddes_1904 acetolactate synthase, small subunit. (162 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (505 aa)
ACZ06993.1TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: geo:Geob_2938 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (529 aa)
ACZ06995.1TIGRFAM: homoaconitate hydratase family protein; 3- isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein; KEGG: 3-isopropylmalate dehydratase; K01703 3- isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Belongs to the aconitase/IPM isomerase family. (435 aa)
ACZ06998.1TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: 3-isopropylmalate dehydratase small subunit; K01704 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Belongs to the LeuD family. (181 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa)
ACZ07000.1PFAM: aminotransferase class I and II; KEGG: dvm:DvMF_3003 putative transcriptional regulator, GntR family. (396 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (359 aa)
ACZ07054.1TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: hac:Hac_0304 hypothetical protein. (175 aa)
ACZ07055.1TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gme:Gmet_2988 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (601 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: hypothetical protein; K00927 phosphoglycerate kinase. (399 aa)
ACZ07115.1Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: nmc:NMC2137 glyceraldehyde 3-phosphate dehydrogenase C; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa)
ACZ07119.1PFAM: ROK family protein; KEGG: sde:Sde_2639 fructokinase. (293 aa)
ACZ07142.1PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pca:Pcar_2295 putative oxidoreductase. (413 aa)
ACZ07190.1PFAM: Domain of unknown function DUF1957; glycoside hydrolase family 57; KEGG: ank:AnaeK_1135 domain of unknown function DUF1957; Belongs to the glycosyl hydrolase 57 family. (528 aa)
ACZ07204.1PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: sat:SYN_02264 UDP-sugar diphosphatase / 5'- nucleotidase; Belongs to the 5'-nucleotidase family. (489 aa)
ACZ07233.1TIGRFAM: NAD pyrophosphatase/5'-nucleotidase NadN; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: hiq:CGSHiGG_03645 NAD nucleotidase; Belongs to the 5'-nucleotidase family. (591 aa)
ACZ07258.1KEGG: ASNS; asparagine synthetase; K01953 asparagine synthase (glutamine-hydrolysing); TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (528 aa)
ACZ07277.1TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE2513 putative hydrolase. (269 aa)
ACZ07373.1TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: gur:Gura_3720 acetolactate synthase, large subunit, biosynthetic type. (566 aa)
ACZ07374.1TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pha:PSHAb0463 acetolactate synthase 3 regulatory subunit. (162 aa)
ACZ07379.1Ketose-bisphosphate aldolase; KEGG: ype:YPO3960 hypothetical protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (277 aa)
ACZ07450.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (330 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa)
ACZ07524.1TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: asu:Asuc_1597 ribose 5-phosphate isomerase B. (149 aa)
ACZ07529.1PFAM: ketose-bisphosphate aldolase class-II; KEGG: pmu:PM1373 hypothetical protein. (292 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (350 aa)
ACZ07612.1Branched-chain-amino-acid transaminase; PFAM: aminotransferase class IV; KEGG: dar:Daro_3294 branched-chain amino acid aminotransferase. (312 aa)
ACZ07640.13-carboxymuconate cyclase-like protein; KEGG: sde:Sde_1446 hypothetical protein. (338 aa)
ACZ07665.1TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_2748 putative trifunctional 2- polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein. (761 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (335 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (297 aa)
ACZ07891.1TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dat:HRM2_35960 HemD. (493 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gur:Gura_4245 glutamate-1-semialdehyde aminotransferase. (434 aa)
ACZ07895.1Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: ppd:Ppro_0442 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (325 aa)
ACZ07971.1PFAM: ROK family protein; KEGG: fph:Fphi_0224 ROK family protein. (316 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (513 aa)
ACZ08047.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (150 aa)
ACZ08329.1PFAM: Transketolase domain protein; KEGG: gur:Gura_0491 transketolase domain-containing protein. (273 aa)
ACZ08330.1PFAM: Transketolase central region; Transketolase domain protein; KEGG: gur:Gura_0492 transketolase, central region. (314 aa)
ACZ08377.1PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: sfr:Sfri_1898 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (863 aa)
ACZ08406.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (659 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
asnAKEGG: aspartate--ammonia ligase; K01914 aspartate--ammonia ligase; TIGRFAM: aspartate/ammonia ligase; PFAM: aspartate--ammonia ligase. (336 aa)
ACZ08486.1PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sat:SYN_02446 glycerol-3-phosphate dehydrogenase. (478 aa)
ACZ08500.1KEGG: mxa:MXAN_2888 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB. (443 aa)
ACZ08504.1TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: abu:Abu_2153 phosphoglycolate phosphatase. (217 aa)
ACZ08508.1PFAM: ketose-bisphosphate aldolase class-II; KEGG: cko:CKO_03797 hypothetical protein. (289 aa)
ACZ08567.1TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (289 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
ACZ08574.1Pyruvate kinase; KEGG: vha:VIBHAR_00829 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (469 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa)
ACZ08607.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
ACZ08641.1Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)
ACZ08651.1TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: asa:ASA_3652 purine nucleoside phosphorylase. (232 aa)
ACZ08663.1PFAM: Nucleotidyl transferase; KEGG: sat:SYN_01031 mannose-1-phosphate guanylyltransferase. (357 aa)
ACZ08664.1KEGG: esa:ESA_01679 hypothetical protein; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I. (319 aa)
ACZ08711.1PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (257 aa)
ACZ08725.1PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: apj:APJL_2030 ubiquinone/menaquinone biosynthesis methyltransferase. (186 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa)
argJArginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (291 aa)
argDKEGG: sat:SYN_02155 acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (387 aa)
ACZ08765.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (331 aa)
ACZ08801.1PFAM: diacylglycerol kinase; phosphoesterase PA- phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: gme:Gmet_2369 phosphoesterase, PA-phosphatase related. (262 aa)
ACZ08803.1PFAM: hydroxymethylglutaryl-coenzyme A reductase; KEGG: vsa:VSAL_II0253 putative 3-hydroxy-3- methylglutaryl coenzyme a reductase. (424 aa)
ACZ08804.1PFAM: UbiA prenyltransferase; KEGG: plu:plu4506 prenyltransferase. (300 aa)
ACZ08810.1KEGG: wsu:WS1766 fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (280 aa)
ACZ08811.1TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: nis:NIS_0837 fumarate/tartrate hydratase, beta subunit. (181 aa)
ACZ08820.1TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: stm:STM3254 putative fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (306 aa)
ACZ08824.1TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: tdn:Suden_1866 histidinol phosphate phosphatase, HisJ; Belongs to the PHP hydrolase family. HisK subfamily. (268 aa)
ACZ08838.1Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (836 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (207 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: dal:Dalk_0486 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (334 aa)
fbpPFAM: fructose-16-bisphosphatase; KEGG: dat:HRM2_08610 Fbp1. (648 aa)
ACZ08888.1Fructose-1,6-bisphosphate aldolase, class II; KEGG: pca:Pcar_2253 fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (325 aa)
ACZ08898.1Ribulose-phosphate 3-epimerase; KEGG: gme:Gmet_0067 ribulose-5-phosphate 3- epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'- phosphate decarboxylase; Belongs to the ribulose-phosphate 3-epimerase family. (211 aa)
ACZ08901.1KEGG: spe:Spro_3998 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (184 aa)
ACZ08925.1PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: dde:Dde_3034 L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (403 aa)
ACZ08960.1KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. (1244 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa)
purCKEGG: dno:DNO_1112 phosphoribosylaminoimidazole- succinocarboxamidesynthase; TIGRFAM: phosphoribosylaminoimidazole- succinocarboxamide synthase; PFAM: SAICAR synthetase. (235 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (475 aa)
purMKEGG: dno:DNO_1113 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo- ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (331 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (189 aa)
purHKEGG: har:HEAR0255 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region. (500 aa)
purDPhosphoribosylamine/glycine ligase; KEGG: dno:DNO_0940 phosphoribosylglycinamide synthetase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (416 aa)
glgCNucleotidyl transferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (418 aa)
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (473 aa)
ACZ09002.1KEGG: vfm:VFMJ11_2290 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa)
ACZ09004.1TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ADL; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa)
ACZ09007.1TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: dal:Dalk_3952 aconitate hydratase. (644 aa)
ACZ09008.1PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: aha:AHA_1152 isocitrate dehydrogenase. (333 aa)
ACZ09009.1PFAM: Citrate synthase; KEGG: noc:Noc_2628 methylcitrate synthase. (441 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (289 aa)
ACZ09027.1PFAM: tRNA synthetase class II (G H P and S); KEGG: gbm:Gbem_0553 histidyl-tRNA synthetase. (375 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (205 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmw:Mmwyl1_1133 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa)
hisBPFAM: imidazoleglycerol-phosphate dehydratase; KEGG: azc:AZC_4502 imidazoleglycerol-phosphate dehydratase. (196 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa)
hisAKEGG: cco:CCC13826_0444 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. (237 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisITIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: nis:NIS_1544 histidine biosynthesis bifunctional protein HisI; In the N-terminal section; belongs to the PRA-CH family. (217 aa)
ACZ09036.1TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: abu:Abu_1904 histidinol-phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (279 aa)
ACZ09043.1TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: gsu:GSU1487 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (314 aa)
ACZ09063.1Sugar-phosphate isomerase, RpiB/LacA/LacB family; KEGG: ribose 5-phosphate isomerase B family protein; K01808 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (143 aa)
ACZ09092.1PFAM: aminotransferase class I and II; KEGG: ftn:FTN_0410 aspartate aminotransferase. (396 aa)
ACZ09122.1KEGG: nis:NIS_1040 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (497 aa)
argHTIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pca:Pcar_2418 argininosuccinate lyase. (461 aa)
argGKEGG: argininosuccinate synthase; K01940 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
ACZ09154.1KEGG: dol:Dole_3236 siroheme synthase. (145 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
ACZ09193.1TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mca:MCA2040 glutamate synthase subunit beta. (482 aa)
ACZ09194.1PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: glo:Glov_3016 glutamate synthase (ferredoxin). (1483 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa)
aroEShikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa)
ACZ09228.1Chorismate mutase; KEGG: vsp:VS_0556 P-protein [includes: chorismate mutase,Prephenatedehydratase]; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase. (378 aa)
ACZ09239.1KEGG: bba:Bd1150 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; Belongs to the PEP-utilizing enzyme family. (880 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
ACZ09253.1TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: glo:Glov_0507 UTP-glucose-1-phosphate uridylyltransferase. (296 aa)
ACZ09254.1TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: pca:Pcar_2593 dTDP-glucose 4,6-dehydratase. (398 aa)
ACZ09255.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (286 aa)
ACZ09256.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (189 aa)
ACZ09264.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (290 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (354 aa)
ACZ09279.1PFAM: Prephenate dehydrogenase; KEGG: maq:Maqu_1025 3-phosphoshikimate 1- carboxyvinyltransferase. (282 aa)
ACZ09280.1Phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: gme:Gmet_0346 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. (340 aa)
ACZ09292.1PFAM: Polyprenyl synthetase; KEGG: spl:Spea_2990 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (290 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (73 aa)
ACZ09317.1TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: pca:Pcar_1437 malonyl CoA-acyl carrier protein transacylase. (301 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (318 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (255 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (300 aa)
ACZ09544.1KEGG: sat:SYN_00123 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein. (528 aa)
fabVTrans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa)
ACZ09594.1Ketose-bisphosphate aldolase; KEGG: eca:ECA0338 hypothetical protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (287 aa)
ACZ09595.1KEGG: eca:ECA0339 sugar-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (293 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)
ACZ09622.1PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hiq:CGSHiGG_00235 putative NAD(P)H oxidoreductase. (184 aa)
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (400 aa)
ACZ09624.1KEGG: apa:APP7_0407 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. (211 aa)
ACZ09625.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (363 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (155 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa)
ACZ09652.1PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: alpha-amylase. (481 aa)
ACZ09655.1KEGG: geo:Geob_1889 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77. (496 aa)
ACZ09800.1Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: dal:Dalk_2294 glyoxylate reductase. (320 aa)
ACZ09812.1PFAM: aminotransferase class I and II; KEGG: ypg:YpAngola_A2760 aminotransferase, classes I and II. (386 aa)
ACZ09814.1KEGG: dol:Dole_0983 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (247 aa)
ACZ09819.1Tetrahydrodipicolinate succinyltransferase domain protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (231 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (241 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (332 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (285 aa)
ACZ09833.1TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: hhe:HH0618 aspartate kinase; Belongs to the aspartokinase family. (400 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (435 aa)
ACZ09847.1KEGG: spe:Spro_4277 glucose-6-phosphate isomerase- like protein. (258 aa)
ACZ09853.1PFAM: glucose-6-phosphate isomerase; KEGG: spe:Spro_4276 glucose-6-phosphate isomerase. (192 aa)
ACZ09856.1KEGG: sfu:Sfum_2173 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (406 aa)
ACZ09857.1PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: glo:Glov_1214 homoserine dehydrogenase. (398 aa)
ACZ09876.1PFAM: aspartate/glutamate/uridylate kinase; KEGG: vok:COSY_0382 glutamate 5-kinase. (248 aa)
ACZ09892.1PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein Ig domain protein region domain protein; SMART: alpha amylase catalytic sub domain; KEGG: vfi:VF_2049 maltodextrin glucosidase; Belongs to the glycosyl hydrolase 13 family. (797 aa)
ACZ09903.1TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: dat:HRM2_44240 Gph2. (216 aa)
ACZ09905.1TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gur:Gura_3907 cysteine synthase A. (304 aa)
ACZ09914.1TIGRFAM: glucokinase, ROK family; PFAM: ROK family protein; KEGG: rlt:Rleg2_5489 ROK family protein. (314 aa)
ACZ09923.1PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12- binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: gsu:GSU2921 5-methyltetrahydrofolate- homocysteine methyltransferase, truncation. (791 aa)
ACZ09959.1KEGG: bja:bll5145 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I. (314 aa)
ACZ10066.1PFAM: iron-containing alcohol dehydrogenase; KEGG: shw:Sputw3181_2860 iron-containing alcohol dehydrogenase. (382 aa)
ACZ10090.1PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: alpha-amylase. (480 aa)
ACZ10121.1TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gme:Gmet_2988 cysteine synthase. (302 aa)
ACZ10140.1Anthranilate synthase; PFAM: Chorismate binding-like; KEGG: ccv:CCV52592_1683 anthranilate synthase component 1 (anthranilate synthasecomponent I). (419 aa)
ACZ10141.1TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cff:CFF8240_0351 anthranilate synthase component II. (197 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)
ACZ10143.1PFAM: Indole-3-glycerol phosphate synthase; KEGG: abu:Abu_0850 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (244 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cco:CCC13826_0970 N- (5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (196 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (252 aa)
ACZ10150.1PFAM: FAD linked oxidase domain protein; KEGG: nam:NAMH_0817 glycolate oxidase subunit GlcD. (470 aa)
ACZ10160.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (357 aa)
ACZ10161.1PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: scl:sce4837 putative phosphoglucomutase/phosphomannomutase. (573 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (504 aa)
ACZ10203.1PFAM: Transketolase domain protein; Transketolase central region; KEGG: cko:CKO_00493 hypothetical protein. (317 aa)
ACZ10204.1PFAM: Transketolase domain protein; KEGG: efe:EFER_0869 putative carbohydrate degradation enzyme. (277 aa)
ACZ10233.1Serine acetyltransferase-like protein; KEGG: cjd:JJD26997_1249 serine acetyltransferase. (180 aa)
ACZ10270.1KEGG: tau:Tola_1979 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (147 aa)
ACZ10279.1PFAM: short-chain dehydrogenase/reductase SDR; KEGG: oca:OCAR_5704 oxidoreductase, short chain dehydrogenase/reductase family. (264 aa)
ACZ10385.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: kpe:KPK_4469 D-isomer specific 2-hydroxyacid dehydrogenase family protein. (355 aa)
ACZ10436.1Glycerate kinase; KEGG: ccv:CCV52592_0612 glycerate kinase 1; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (381 aa)
ACZ10449.1TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase. (1178 aa)
ACZ10459.1TIGRFAM: acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hypothetical protein. (417 aa)
ACZ10470.1PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: shl:Shal_2747 short-chain dehydrogenase/reductase SDR. (236 aa)
ACZ10472.1TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit. (286 aa)
ACZ10473.1PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dps:DP2103 2-oxoacid ferredoxin oxidoreductase, alpha subunit. (551 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (223 aa)
ACZ10492.1Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (487 aa)
ACZ10599.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (659 aa)
ACZ10612.1KEGG: dal:Dalk_2955 histidinol phosphate phosphatase HisJ family; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa)
ACZ10615.1PFAM: iron-containing alcohol dehydrogenase; KEGG: vfm:VFMJ11_1266 1,3-propanediol dehydrogenase. (384 aa)
ACZ10671.1PFAM: ribulose-phosphate 3-epimerase; KEGG: dde:Dde_2632 ribulose-5-phosphate 3-epimerase. (234 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (210 aa)
ACZ10840.1PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; Oxidoreductase domain; KEGG: bph:Bphy_1594 oxidoreductase domain- containing protein. (337 aa)
ACZ10846.1PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: hso:HS_1576 dehydrogenase. (337 aa)
ACZ10851.1KEGG: hsm:HSM_0819 ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (283 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
ACZ10917.1Coproporphyrinogen dehydrogenase; KEGG: bas:BUsg532 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (468 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (291 aa)
ACZ10958.1PFAM: ribulose-phosphate 3-epimerase; KEGG: cla:Cla_1028 D-ribulose-5-phosphate 3- epimerase. (220 aa)
ACZ10960.1PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: vfm:VFMJ11_2152 neopullulanase; Belongs to the glycosyl hydrolase 13 family. (1012 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: afw:Anae109_2086 glucose-6-phosphate isomerase; Belongs to the GPI family. (448 aa)
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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