(35 nodes) mRNA decay by 5 to 3 exoribonuclease, and TP53 Regulates Transcription of Cell Cycle Genes network (Verticillium alfalfae)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	VDBG_00489	CCR4-NOT transcription complex subunit 3. (650 aa)
	VDBG_01017	Pentatricopeptide repeat protein. (710 aa)
	VDBG_01041	Transcriptional regulator involved in cell cycle regulation. (387 aa)
	VDBG_01042	CUE domain-containing protein. (143 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (80 aa)
	VDBG_02322	YjeF-related protein. (78 aa)
	VDBG_01918	NTP_transf_9 domain-containing protein. (165 aa)
	VDBG_01955	RH73529p. (141 aa)
	VDBG_04151	ATP-dependent RNA helicase ded1; Belongs to the DEAD box helicase family. (676 aa)
	VDBG_04160	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1383 aa)
	VDBG_03481	Topoisomerase II. (759 aa)
	VDBG_03510	ATP-dependent RNA helicase dhh-1; Belongs to the DEAD box helicase family. (390 aa)
	VDBG_05019	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (367 aa)
	VDBG_05100	Uncharacterized protein. (321 aa)
	VDBG_05223	Meiotic coiled-coil protein. (763 aa)
	VDBG_05326	Pumilio domain-containing protein. (1157 aa)
	VDBG_05588	Lsm14a protein. (108 aa)
	VDBG_06107	LSM domain-containing protein. (105 aa)
	VDBG_06302	Uncharacterized protein. (288 aa)
	VDBG_07053	Uncharacterized protein. (1025 aa)
	VDBG_07160	Uncharacterized protein. (221 aa)
	VDBG_06992	Uncharacterized protein. (286 aa)
	VDBG_06994	mRNA-decapping enzyme. (169 aa)
	VDBG_07624	Uncharacterized protein. (167 aa)
	VDBG_07902	General negative regulator of transcription subunit 4. (1569 aa)
	VDBG_08214	Cell differentiation protein rcd1. (305 aa)
	VDBG_08236	Thiamine pyrophosphokinase. (331 aa)
	VDBG_08730	CCR4-NOT transcription complex subunit 8. (525 aa)
	VDBG_08834	ATP-dependent RNA helicase mrh-4. (609 aa)
	VDBG_09319	Uncharacterized protein. (1684 aa)
	VDBG_09631	Uncharacterized protein. (352 aa)
	VDBG_09459	Glucose-repressible alcohol dehydrogenase transcriptional effector. (703 aa)
	VDBG_09512	Uncharacterized protein. (276 aa)
	VDBG_09950	Nudix hydrolase domain-containing protein. (363 aa)
	VDBG_10216	YjeF_N domain-containing protein. (736 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM5	VDBG_01017	C9S8V5	C9S8C9	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Pentatricopeptide repeat protein.	0.999
LSM5	VDBG_01918	C9S8V5	C9SBS5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	NTP_transf_9 domain-containing protein.	0.590
LSM5	VDBG_01955	C9S8V5	C9SBW2	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	RH73529p.	0.999
LSM5	VDBG_02322	C9S8V5	C9SA00	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	YjeF-related protein.	0.589
LSM5	VDBG_03481	C9S8V5	C9SFW8	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Topoisomerase II.	0.999
LSM5	VDBG_03510	C9S8V5	C9SFZ7	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	ATP-dependent RNA helicase dhh-1; Belongs to the DEAD box helicase family.	0.798
LSM5	VDBG_04160	C9S8V5	C9SFV6	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.782
LSM5	VDBG_05100	C9S8V5	C9SJX3	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Uncharacterized protein.	0.999
LSM5	VDBG_06107	C9S8V5	C9SMI3	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	LSM domain-containing protein.	0.999
LSM5	VDBG_06302	C9S8V5	C9SN27	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Uncharacterized protein.	0.590
LSM5	VDBG_06992	C9S8V5	C9SR80	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Uncharacterized protein.	0.590
LSM5	VDBG_06994	C9S8V5	C9SR82	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	mRNA-decapping enzyme.	0.590
LSM5	VDBG_07053	C9S8V5	C9SQ18	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Uncharacterized protein.	0.993
LSM5	VDBG_07160	C9S8V5	C9SQC5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Uncharacterized protein.	0.999
LSM5	VDBG_09512	C9S8V5	C9SXL2	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	Uncharacterized protein.	0.861
LSM5	VDBG_10216	C9S8V5	C9SZ91	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	YjeF_N domain-containing protein.	0.782
VDBG_00489	VDBG_01041	C9S643	C9S8P0	CCR4-NOT transcription complex subunit 3.	Transcriptional regulator involved in cell cycle regulation.	0.976
VDBG_00489	VDBG_01042	C9S643	C9S8P1	CCR4-NOT transcription complex subunit 3.	CUE domain-containing protein.	0.964
VDBG_00489	VDBG_03481	C9S643	C9SFW8	CCR4-NOT transcription complex subunit 3.	Topoisomerase II.	0.977
VDBG_00489	VDBG_03510	C9S643	C9SFZ7	CCR4-NOT transcription complex subunit 3.	ATP-dependent RNA helicase dhh-1; Belongs to the DEAD box helicase family.	0.946