(52 nodes) Cortical actin cytoskeleton network (Verticillium alfalfae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VDBG_01965	Uncharacterized protein. (685 aa)
	VDBG_01984	SLA2. (1032 aa)
	VDBG_02010	Beta-chimaerin. (721 aa)
	VDBG_02826	Alpha-actinin-1. (717 aa)
	VDBG_04041	Type I inositol-1,4,5-trisphosphate 5-phosphatase CVP2. (890 aa)
	VDBG_04042	Uncharacterized protein. (93 aa)
	VDBG_04054	Vacuolar protein sorting-associated protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (811 aa)
	VDBG_03485	DH domain-containing protein. (1502 aa)
	VDBG_04196	Actin lateral binding protein. (161 aa)
	VDBG_03567	SNI2. (784 aa)
	VDBG_04294	WD repeat-containing protein. (610 aa)
	VDBG_03734	Zn(2)-C6 fungal-type domain-containing protein. (841 aa)
	VDBG_03758	Uncharacterized protein. (289 aa)
	VDBG_03792	SpaA. (870 aa)
	VDBG_04861	AbpA. (817 aa)
	VDBG_05048	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1655 aa)
	VDBG_04328	Adenylyl cyclase-associated protein; Belongs to the CAP family. (334 aa)
	VDBG_05095	Cytoskeleton assembly control protein SLA1. (1132 aa)
	VDBG_05564	Actin-2; Belongs to the actin family. (439 aa)
	VDBG_05701	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (193 aa)
	VDBG_05839	LIM domain-containing protein. (580 aa)
	VDBG_05999	Tyrosine-protein phosphatase CDC14. (642 aa)
	VDBG_06021	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	VDBG_06672	Calponin. (721 aa)
	VDBG_06873	Uncharacterized protein. (281 aa)
	VDBG_06874	PAN1. (544 aa)
	VDBG_06875	Uncharacterized protein. (211 aa)
	VDBG_07039	Plastin-2. (571 aa)
	VDBG_07170	Myosin-5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1207 aa)
	VDBG_07945	VHS domain-containing protein. (429 aa)
	VDBG_07962	SH3 domain-containing protein. (369 aa)
	VDBG_08012	Uncharacterized protein. (631 aa)
	VDBG_08256	SH3 domain-containing protein. (551 aa)
	VDBG_09716	LDB17. (489 aa)
	VDBG_09513	BAR domain-containing protein. (271 aa)
	VDBG_09318	Septation protein imp2. (562 aa)
	VDBG_08891	Coronin; Belongs to the WD repeat coronin family. (616 aa)
	VDBG_08257	SH3 domain-containing protein. (273 aa)
	VDBG_08665	CRIB domain-containing protein. (787 aa)
	VDBG_00285	Dual specificity protein kinase pom1. (1340 aa)
	VDBG_00338	BAR domain-containing protein. (442 aa)
	VDBG_00464	E3 ubiquitin-protein ligase. (791 aa)
	VDBG_00497	C2 domain-containing protein. (768 aa)
	VDBG_00535	BZZ1. (696 aa)
	VDBG_01314	Myosin regulatory light chain cdc4. (145 aa)
	VDBG_00884	END3. (359 aa)
	VDBG_00150	Cytokinesis protein Cyk3. (1246 aa)
	VDBG_02133	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (389 aa)
	VDBG_01496	UBA/TS-N domain-containing protein. (1262 aa)
	VDBG_01652	Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2368 aa)
	VDBG_01763	WH1 domain-containing protein. (78 aa)
	VDBG_01964	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VDBG_00150	VDBG_00497	C9S8W6	C9S651	Cytokinesis protein Cyk3.	C2 domain-containing protein.	0.414
VDBG_00150	VDBG_09318	C9S8W6	C9SWP3	Cytokinesis protein Cyk3.	Septation protein imp2.	0.948
VDBG_00338	VDBG_00464	C9S5I4	C9S618	BAR domain-containing protein.	E3 ubiquitin-protein ligase.	0.563
VDBG_00338	VDBG_00535	C9S5I4	C9S6B5	BAR domain-containing protein.	BZZ1.	0.645
VDBG_00338	VDBG_00884	C9S5I4	C9S7L4	BAR domain-containing protein.	END3.	0.470
VDBG_00338	VDBG_01763	C9S5I4	C9SBC0	BAR domain-containing protein.	WH1 domain-containing protein.	0.982
VDBG_00338	VDBG_01984	C9S5I4	C9SBZ1	BAR domain-containing protein.	SLA2.	0.527
VDBG_00338	VDBG_02133	C9S5I4	C9S9G1	BAR domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.524
VDBG_00338	VDBG_04054	C9S5I4	C9SFF9	BAR domain-containing protein.	Vacuolar protein sorting-associated protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.593
VDBG_00338	VDBG_04861	C9S5I4	C9SIH9	BAR domain-containing protein.	AbpA.	0.972
VDBG_00338	VDBG_05048	C9S5I4	C9SJ16	BAR domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.785
VDBG_00338	VDBG_05095	C9S5I4	C9SJW8	BAR domain-containing protein.	Cytoskeleton assembly control protein SLA1.	0.710
VDBG_00338	VDBG_07039	C9S5I4	C9SQ04	BAR domain-containing protein.	Plastin-2.	0.612
VDBG_00338	VDBG_07170	C9S5I4	C9SQD5	BAR domain-containing protein.	Myosin-5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.655
VDBG_00338	VDBG_08256	C9S5I4	C9SUN6	BAR domain-containing protein.	SH3 domain-containing protein.	0.603
VDBG_00338	VDBG_09318	C9S5I4	C9SWP3	BAR domain-containing protein.	Septation protein imp2.	0.614
VDBG_00338	VDBG_09513	C9S5I4	C9SXL3	BAR domain-containing protein.	BAR domain-containing protein.	0.979
VDBG_00464	VDBG_00338	C9S618	C9S5I4	E3 ubiquitin-protein ligase.	BAR domain-containing protein.	0.563
VDBG_00464	VDBG_05048	C9S618	C9SJ16	E3 ubiquitin-protein ligase.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.526
VDBG_00497	VDBG_00150	C9S651	C9S8W6	C2 domain-containing protein.	Cytokinesis protein Cyk3.	0.414