(12 nodes) Replisome network (Verticillium alfalfae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VDBG_04644	NPL4. (342 aa)
	VDBG_09397	DNA primase large subunit. (413 aa)
	VDBG_08326	Uncharacterized protein. (129 aa)
	VDBG_08292	Replication factor-A protein. (181 aa)
	VDBG_07512	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (593 aa)
	VDBG_07009	DNA polymerase. (1231 aa)
	VDBG_00356	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (609 aa)
	VDBG_00052	DNA polymerase. (1055 aa)
	VDBG_03346	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (495 aa)
	VDBG_03362	DNA polymerase subunit delta-2. (497 aa)
	VDBG_04642	NPL4. (250 aa)
	VDBG_05197	Ubiquitin fusion degradation protein. (374 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VDBG_00052	VDBG_00356	C9S8I4	C9S5M3	DNA polymerase.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.909
VDBG_00052	VDBG_03346	C9S8I4	C9SDZ0	DNA polymerase.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.979
VDBG_00052	VDBG_03362	C9S8I4	C9SE06	DNA polymerase.	DNA polymerase subunit delta-2.	0.999
VDBG_00052	VDBG_07009	C9S8I4	C9SPX4	DNA polymerase.	DNA polymerase.	0.846
VDBG_00052	VDBG_07512	C9S8I4	C9SRI7	DNA polymerase.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.983
VDBG_00052	VDBG_08292	C9S8I4	C9STM1	DNA polymerase.	Replication factor-A protein.	0.841
VDBG_00052	VDBG_08326	C9S8I4	C9STQ5	DNA polymerase.	Uncharacterized protein.	0.980
VDBG_00052	VDBG_09397	C9S8I4	C9SX97	DNA polymerase.	DNA primase large subunit.	0.983
VDBG_00356	VDBG_00052	C9S5M3	C9S8I4	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA polymerase.	0.909
VDBG_00356	VDBG_03346	C9S5M3	C9SDZ0	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.842
VDBG_00356	VDBG_03362	C9S5M3	C9SE06	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA polymerase subunit delta-2.	0.689
VDBG_00356	VDBG_05197	C9S5M3	C9SK70	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Ubiquitin fusion degradation protein.	0.596
VDBG_00356	VDBG_07009	C9S5M3	C9SPX4	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA polymerase.	0.719
VDBG_00356	VDBG_07512	C9S5M3	C9SRI7	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.701
VDBG_00356	VDBG_08292	C9S5M3	C9STM1	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Replication factor-A protein.	0.999
VDBG_00356	VDBG_08326	C9S5M3	C9STQ5	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Uncharacterized protein.	0.482
VDBG_00356	VDBG_09397	C9S5M3	C9SX97	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA primase large subunit.	0.837
VDBG_03346	VDBG_00052	C9SDZ0	C9S8I4	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	DNA polymerase.	0.979
VDBG_03346	VDBG_00356	C9SDZ0	C9S5M3	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.842
VDBG_03346	VDBG_03362	C9SDZ0	C9SE06	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	DNA polymerase subunit delta-2.	0.943