(13 nodes) Telomeric DNA binding network (Verticillium alfalfae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VDBG_01541	TRF domain-containing protein. (874 aa)
	VDBG_00038	Telo_bind domain-containing protein. (696 aa)
	VDBG_01811	EST1_DNA_bind domain-containing protein. (734 aa)
	VDBG_04487	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (333 aa)
	VDBG_04702	Telomere_reg-2 domain-containing protein. (805 aa)
	VDBG_06882	Uncharacterized protein. (881 aa)
	VDBG_07227	DNA repair protein RAD50. (1195 aa)
	VDBG_08037	OB-fold nucleic acid binding domain-containing protein. (246 aa)
	VDBG_08268	Ku70. (645 aa)
	VDBG_08803	Elicitor protein. (324 aa)
	VDBG_08864	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (722 aa)
	VDBG_00356	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (609 aa)
	VDBG_00631	Translin. (256 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VDBG_00038	VDBG_00356	C9S8C1	C9S5M3	Telo_bind domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.615
VDBG_00038	VDBG_04487	C9S8C1	C9SHF5	Telo_bind domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.967
VDBG_00038	VDBG_07227	C9S8C1	C9SQJ2	Telo_bind domain-containing protein.	DNA repair protein RAD50.	0.505
VDBG_00356	VDBG_00038	C9S5M3	C9S8C1	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Telo_bind domain-containing protein.	0.615
VDBG_00356	VDBG_04487	C9S5M3	C9SHF5	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.884
VDBG_00356	VDBG_07227	C9S5M3	C9SQJ2	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA repair protein RAD50.	0.855
VDBG_00356	VDBG_08268	C9S5M3	C9STJ7	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Ku70.	0.855
VDBG_00356	VDBG_08864	C9S5M3	C9SVD9	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.530
VDBG_01811	VDBG_04487	C9SBG8	C9SHF5	EST1_DNA_bind domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.833
VDBG_01811	VDBG_06882	C9SBG8	C9SPQ7	EST1_DNA_bind domain-containing protein.	Uncharacterized protein.	0.617
VDBG_01811	VDBG_08268	C9SBG8	C9STJ7	EST1_DNA_bind domain-containing protein.	Ku70.	0.493
VDBG_01811	VDBG_08864	C9SBG8	C9SVD9	EST1_DNA_bind domain-containing protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.587
VDBG_04487	VDBG_00038	C9SHF5	C9S8C1	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Telo_bind domain-containing protein.	0.967
VDBG_04487	VDBG_00356	C9SHF5	C9S5M3	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.884
VDBG_04487	VDBG_01811	C9SHF5	C9SBG8	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	EST1_DNA_bind domain-containing protein.	0.833
VDBG_04487	VDBG_06882	C9SHF5	C9SPQ7	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.936
VDBG_04487	VDBG_07227	C9SHF5	C9SQJ2	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	DNA repair protein RAD50.	0.664
VDBG_04487	VDBG_08268	C9SHF5	C9STJ7	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Ku70.	0.876
VDBG_04487	VDBG_08864	C9SHF5	C9SVD9	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.883
VDBG_06882	VDBG_01811	C9SPQ7	C9SBG8	Uncharacterized protein.	EST1_DNA_bind domain-containing protein.	0.617