(41 nodes) Regulation of mRNA catabolic process network (Verticillium alfalfae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	VDBG_09698	RNP domain-containing protein. (572 aa)
	VDBG_00489	CCR4-NOT transcription complex subunit 3. (650 aa)
	VDBG_01246	DCS2. (241 aa)
	VDBG_00700	Exosome complex exonuclease RRP40. (245 aa)
	VDBG_02100	RNA binding protein. (450 aa)
	VDBG_02195	Exosome complex exonuclease RRP43. (340 aa)
	VDBG_01918	NTP_transf_9 domain-containing protein. (165 aa)
	VDBG_01956	PAB-dependent poly(A)-specific ribonuclease subunit PAN3. (438 aa)
	VDBG_03477	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1048 aa)
	VDBG_03481	Topoisomerase II. (759 aa)
	VDBG_03613	3'-5' exonuclease domain-containing protein. (894 aa)
	VDBG_03680	RNase_PH domain-containing protein. (373 aa)
	VDBG_04852	DNA-directed RNA polymerase II subunit RPB7. (177 aa)
	VDBG_04945	Uncharacterized protein. (301 aa)
	VDBG_05130	RPOL4c domain-containing protein. (160 aa)
	VDBG_05223	Meiotic coiled-coil protein. (763 aa)
	VDBG_05326	Pumilio domain-containing protein. (1157 aa)
	VDBG_05689	Uncharacterized protein. (650 aa)
	VDBG_05847	RNase_PH domain-containing protein. (249 aa)
	VDBG_06093	RRM domain-containing protein. (37 aa)
	VDBG_06302	Uncharacterized protein. (288 aa)
	VDBG_06740	Exosome complex exonuclease RRP45. (271 aa)
	VDBG_06774	Pumilio domain-containing protein. (1004 aa)
	VDBG_06775	Predicted protein. (128 aa)
	VDBG_06846	Pumilio domain-containing protein. (852 aa)
	VDBG_07046	G-protein beta subunit. (316 aa)
	VDBG_07160	Uncharacterized protein. (221 aa)
	VDBG_06992	Uncharacterized protein. (286 aa)
	VDBG_06994	mRNA-decapping enzyme. (169 aa)
	VDBG_07764	GTP-binding protein. (590 aa)
	VDBG_08318	Caffeine-induced death protein. (1079 aa)
	VDBG_08625	VTS1. (214 aa)
	VDBG_08626	VTS1. (329 aa)
	VDBG_08730	CCR4-NOT transcription complex subunit 8. (525 aa)
	VDBG_08903	Predicted protein. (447 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1118 aa)
	VDBG_09288	Eukaryotic peptide chain release factor GTP-binding subunit. (659 aa)
	VDBG_09319	Uncharacterized protein. (1684 aa)
	VDBG_09459	Glucose-repressible alcohol dehydrogenase transcriptional effector. (703 aa)
	VDBG_09512	Uncharacterized protein. (276 aa)
	VDBG_00262	Exosome complex exonuclease RRP4. (353 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAN2	VDBG_01956	C9SWJ6	C9SBW3	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	PAB-dependent poly(A)-specific ribonuclease subunit PAN3.	0.999
PAN2	VDBG_07160	C9SWJ6	C9SQC5	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.437
PAN2	VDBG_08730	C9SWJ6	C9SV05	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	CCR4-NOT transcription complex subunit 8.	0.624
PAN2	VDBG_08903	C9SWJ6	C9SVH8	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Predicted protein.	0.513
PAN2	VDBG_09319	C9SWJ6	C9SWP4	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.537
PAN2	VDBG_09459	C9SWJ6	C9SXF9	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Glucose-repressible alcohol dehydrogenase transcriptional effector.	0.742
VDBG_00262	VDBG_00700	C9S555	C9S6Y1	Exosome complex exonuclease RRP4.	Exosome complex exonuclease RRP40.	0.999
VDBG_00262	VDBG_01918	C9S555	C9SBS5	Exosome complex exonuclease RRP4.	NTP_transf_9 domain-containing protein.	0.602
VDBG_00262	VDBG_02195	C9S555	C9S9M3	Exosome complex exonuclease RRP4.	Exosome complex exonuclease RRP43.	0.999
VDBG_00262	VDBG_03613	C9S555	C9SGG4	Exosome complex exonuclease RRP4.	3'-5' exonuclease domain-containing protein.	0.412
VDBG_00262	VDBG_03680	C9S555	C9SGU9	Exosome complex exonuclease RRP4.	RNase_PH domain-containing protein.	0.999
VDBG_00262	VDBG_05847	C9S555	C9SLS3	Exosome complex exonuclease RRP4.	RNase_PH domain-containing protein.	0.999
VDBG_00262	VDBG_06302	C9S555	C9SN27	Exosome complex exonuclease RRP4.	Uncharacterized protein.	0.602
VDBG_00262	VDBG_06740	C9S555	C9SPB5	Exosome complex exonuclease RRP4.	Exosome complex exonuclease RRP45.	0.999
VDBG_00262	VDBG_06992	C9S555	C9SR80	Exosome complex exonuclease RRP4.	Uncharacterized protein.	0.602
VDBG_00262	VDBG_06994	C9S555	C9SR82	Exosome complex exonuclease RRP4.	mRNA-decapping enzyme.	0.602
VDBG_00262	VDBG_08903	C9S555	C9SVH8	Exosome complex exonuclease RRP4.	Predicted protein.	0.536
VDBG_00262	VDBG_09512	C9S555	C9SXL2	Exosome complex exonuclease RRP4.	Uncharacterized protein.	0.869
VDBG_00489	VDBG_03481	C9S643	C9SFW8	CCR4-NOT transcription complex subunit 3.	Topoisomerase II.	0.977
VDBG_00489	VDBG_08730	C9S643	C9SV05	CCR4-NOT transcription complex subunit 3.	CCR4-NOT transcription complex subunit 8.	0.995