(105 nodes) WD40 repeat network (Verticillium alfalfae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VDBG_05983	WD repeat-containing protein. (716 aa)
	VDBG_10030	Cell division control protein. (638 aa)
	VDBG_10017	WD repeat-containing protein. (904 aa)
	VDBG_09866	WD repeat-containing protein. (1145 aa)
	VDBG_09806	WD repeat-containing protein. (565 aa)
	VDBG_09412	Transcription initiation factor TFIID subunit 5. (759 aa)
	VDBG_09345	WD repeat-containing protein srw1. (587 aa)
	VDBG_08951	Nuclear distribution protein nudF. (391 aa)
	VDBG_08891	Coronin; Belongs to the WD repeat coronin family. (616 aa)
	VDBG_08886	WD repeat-containing protein. (564 aa)
	VDBG_08787	Polyadenylation factor subunit 2. (518 aa)
	VDBG_08695	F-box/WD repeat-containing protein. (673 aa)
	VDBG_08650	Transcriptional repressor rco-1. (103 aa)
	VDBG_08247	U3 small nucleolar RNA-associated protein. (979 aa)
	asa1	ASTRA-associated protein 1; Component of the ASTRA complex involved in chromatin remodeling. (404 aa)
	VDBG_08219	Transport protein sec-13; Belongs to the WD repeat SEC13 family. (337 aa)
	VDBG_07980	Catabolite repression protein creC. (389 aa)
	VDBG_07971	WD repeat-containing protein. (634 aa)
	VDBG_07851	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1054 aa)
	VDBG_07823	Guanine nucleotide-binding protein subunit beta. (324 aa)
	VDBG_07798	Cell cycle control protein cwf8. (538 aa)
	VDBG_07795	Ribosome assembly protein RRB1. (492 aa)
	VDBG_07791	WD repeat-containing protein. (930 aa)
	VDBG_07458	Coatomer subunit alpha. (1052 aa)
	VDBG_06998	WD repeat-containing protein. (384 aa)
	VDBG_07405	Set1 complex component swd1. (435 aa)
	VDBG_07382	WD repeat-containing protein slp1. (600 aa)
	VDBG_07354	WD repeat-containing protein. (1378 aa)
	VDBG_07350	WD_REPEATS_REGION domain-containing protein. (840 aa)
	VDBG_07338	U3 small nucleolar RNA-associated protein. (911 aa)
	VDBG_07046	G-protein beta subunit. (316 aa)
	VDBG_07016	MAK11. (494 aa)
	VDBG_06695	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1525 aa)
	VDBG_06084	Periodic tryptophan protein. (308 aa)
	VDBG_06071	Cytoplasmic dynein 1 intermediate chain 1. (487 aa)
	VDBG_06021	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	VDBG_06018	Will die slowly. (236 aa)
	VDBG_01172	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (837 aa)
	VDBG_00496	U3 small nucleolar RNA-associated protein. (481 aa)
	VDBG_00552	DNA excision repair protein ERCC-8. (278 aa)
	VDBG_00674	WD repeat-containing protein pop3. (318 aa)
	VDBG_00805	WD_REPEATS_REGION domain-containing protein. (399 aa)
	VDBG_00929	Phosphoinositide 3-kinase regulatory subunit 4. (1521 aa)
	VDBG_00944	Mitochondrial division protein. (659 aa)
	VDBG_01049	Peroxisomal targeting signal 2 receptor. (345 aa)
	VDBG_00145	Microtubule-associated protein ytm1. (330 aa)
	VDBG_00164	Elongator complex protein. (771 aa)
	VDBG_02189	WD repeat-containing protein. (417 aa)
	VDBG_02200	WD repeat and FYVE domain-containing protein. (2531 aa)
	VDBG_02255	WD_REPEATS_REGION domain-containing protein. (455 aa)
	VDBG_02288	WD repeat domain phosphoinositide-interacting protein. (318 aa)
	VDBG_02383	WD repeat-containing protein. (515 aa)
	VDBG_01621	Mitotic checkpoint protein BUB3. (353 aa)
	VDBG_01678	WD repeat-containing protein. (1492 aa)
	VDBG_01701	Poly(A)+ RNA export protein. (358 aa)
	VDBG_01748	WD repeat-containing protein mip1. (1430 aa)
	VDBG_01876	Ubiquitin homeostasis protein lub1. (771 aa)
	VDBG_01877	Serine-threonine kinase receptor-associated protein. (313 aa)
	VDBG_01878	Transcription factor SPT8. (571 aa)
	VDBG_01907	F-box domain-containing protein. (593 aa)
	VDBG_02032	LEC14B protein. (497 aa)
	VDBG_02862	F-box/WD repeat-containing protein 1A. (1033 aa)
	VDBG_03032	WD repeat-containing protein. (1081 aa)
	VDBG_02521	Sulfur controller 2. (646 aa)
	VDBG_02549	F-box/WD repeat-containing protein 1A. (262 aa)
	CIA1	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (432 aa)
	VDBG_03419	WD repeat domain phosphoinositide-interacting protein. (340 aa)
	VDBG_03904	Pre-mRNA-processing factor 17. (514 aa)
	VDBG_03980	WD repeat-containing protein. (584 aa)
	VDBG_04006	Meiosis-specific APC/C activator protein AMA1. (608 aa)
	VDBG_04014	WD repeat-containing protein. (1004 aa)
	VDBG_04041	Type I inositol-1,4,5-trisphosphate 5-phosphatase CVP2. (890 aa)
	VDBG_04053	WD repeat-containing protein. (628 aa)
	VDBG_04107	U3 small nucleolar RNA-associated protein. (906 aa)
	VDBG_04153	Ribosomal RNA-processing protein. (529 aa)
	VDBG_04159	Histone acetyltransferase type B subunit 2. (436 aa)
	VDBG_04201	Uncharacterized protein. (1043 aa)
	VDBG_04208	WD repeat-containing protein. (707 aa)
	VDBG_03567	SNI2. (784 aa)
	VDBG_04244	Periodic tryptophan protein. (160 aa)
	TIF34	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (333 aa)
	VDBG_04294	WD repeat-containing protein. (610 aa)
	VDBG_04307	WD repeat-containing protein. (356 aa)
	VDBG_03731	WD repeat-containing protein. (318 aa)
	VDBG_03760	Sporulation protein. (968 aa)
	VDBG_03797	Chromatin assembly factor 1 subunit B. (693 aa)
	VDBG_04568	Eukaryotic ribosome biogenesis protein. (456 aa)
	VDBG_04581	Peptidyl-prolyl cis-trans isomerase cyp15. (496 aa)
	VDBG_04598	NACHT and WD domain-containing protein. (456 aa)
	VDBG_04609	U3 small nucleolar RNA-associated protein. (568 aa)
	VDBG_04722	DOM34-interacting protein. (977 aa)
	TRM82	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (549 aa)
	VDBG_04888	U4/U6 small nuclear ribonucleoprotein Prp4. (515 aa)
	VDBG_05085	Pre-mRNA-splicing factor prp46. (190 aa)
	VDBG_05086	Pre-mRNA-splicing factor prp46. (290 aa)
	VDBG_05099	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (460 aa)
	VDBG_05113	THO complex subunit 3. (273 aa)
	VDBG_05187	Transport protein SEC31. (1007 aa)
	VDBG_05300	WD repeat-containing protein. (1027 aa)
	VDBG_05386	SOF1. (448 aa)
	VDBG_05403	Uncharacterized protein. (640 aa)
	VDBG_05450	Striatin Pro11. (844 aa)
	VDBG_05543	Meiotic recombination protein rec14. (310 aa)
	VDBG_05545	WD repeat-containing protein. (403 aa)
	VDBG_05546	Minichromosome loss protein. (835 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIA1	VDBG_03904	C9SE56	C9SF09	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.	Pre-mRNA-processing factor 17.	0.415
CIA1	VDBG_08650	C9SE56	C9SUS5	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.	Transcriptional repressor rco-1.	0.400
TIF34	VDBG_01877	C9SGT8	C9SBN4	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Serine-threonine kinase receptor-associated protein.	0.464
TIF34	VDBG_03904	C9SGT8	C9SF09	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Pre-mRNA-processing factor 17.	0.440
TIF34	VDBG_04159	C9SGT8	C9SFV5	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Histone acetyltransferase type B subunit 2.	0.440
TIF34	VDBG_04244	C9SGT8	C9SGI5	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Periodic tryptophan protein.	0.549
TIF34	VDBG_04888	C9SGT8	C9SIK6	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	U4/U6 small nuclear ribonucleoprotein Prp4.	0.444
TIF34	VDBG_05086	C9SGT8	C9SJV9	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Pre-mRNA-splicing factor prp46.	0.400
TIF34	VDBG_06018	C9SGT8	C9SM94	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Will die slowly.	0.470
TIF34	VDBG_07046	C9SGT8	C9SQ11	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	G-protein beta subunit.	0.988
TIF34	VDBG_08219	C9SGT8	C9STJ4	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Transport protein sec-13; Belongs to the WD repeat SEC13 family.	0.475
TIF34	VDBG_08650	C9SGT8	C9SUS5	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Transcriptional repressor rco-1.	0.454
TIF34	VDBG_09412	C9SGT8	C9SXB2	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Transcription initiation factor TFIID subunit 5.	0.410
TRM82	VDBG_00145	C9SI71	C9S8W1	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	Microtubule-associated protein ytm1.	0.459
TRM82	VDBG_02189	C9SI71	C9S9L7	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	WD repeat-containing protein.	0.606
TRM82	VDBG_02383	C9SI71	C9SA61	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	WD repeat-containing protein.	0.438
TRM82	VDBG_04107	C9SI71	C9SFQ3	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	U3 small nucleolar RNA-associated protein.	0.474
TRM82	VDBG_04153	C9SI71	C9SFU9	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	Ribosomal RNA-processing protein.	0.595
TRM82	VDBG_04159	C9SI71	C9SFV5	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	Histone acetyltransferase type B subunit 2.	0.495
TRM82	VDBG_04244	C9SI71	C9SGI5	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	Periodic tryptophan protein.	0.671