(53 nodes) Winged helix-like DNA-binding domain superfamily network (Verticillium alfalfae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	VDBG_09966	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (390 aa)
	VDBG_01126	RNA-binding La domain-containing protein. (368 aa)
	VDBG_01138	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (527 aa)
	VDBG_01165	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (444 aa)
	VDBG_00448	40S ribosomal protein S19. (152 aa)
	VDBG_01071	Developmental regulator flbA. (417 aa)
	VDBG_01085	Vacuolar membrane-associated protein iml-1. (1992 aa)
	VDBG_02265	26S proteasome regulatory subunit RPN5. (492 aa)
	VDBG_01503	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (665 aa)
	VDBG_01627	zf-RING-like domain-containing protein. (333 aa)
	VDBG_01669	Rho1 guanine nucleotide exchange factor 1. (1178 aa)
	VDBG_01708	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (442 aa)
	VDBG_01904	SWIRM domain-containing protein. (387 aa)
	VDBG_03076	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (231 aa)
	VDBG_03345	Transcription factor prr1. (479 aa)
	VDBG_03851	COP9 signalosome complex subunit 12. (435 aa)
	VDBG_03495	Vacuolar protein-sorting-associated protein. (541 aa)
	VDBG_03528	H15 domain-containing protein. (208 aa)
	VDBG_04171	Sak1. (589 aa)
	VDBG_04189	Rho-GTPase-activating protein. (899 aa)
	VDBG_04268	Forkhead domain-containing protein. (1136 aa)
	VDBG_03651	Pex14_N domain-containing protein. (275 aa)
	VDBG_04647	Pre-mRNA-splicing helicase BRR2. (2194 aa)
	VDBG_04764	ATP-dependent helicase SGS1. (1714 aa)
	VDBG_04809	COP9 signalosome complex subunit 4. (298 aa)
	VDBG_04858	Cell division control protein; Belongs to the CDC6/cdc18 family. (605 aa)
	VDBG_04936	Lysine-specific histone demethylase. (989 aa)
	VDBG_05035	Cullin-3; Belongs to the cullin family. (815 aa)
	VDBG_04330	Transcription regulatory protein SWI3. (644 aa)
	VDBG_04356	Uncharacterized protein. (107 aa)
	VDBG_04362	Cullin-1. (112 aa)
	VDBG_04463	Anaphase-promoting complex subunit 2; Belongs to the cullin family. (357 aa)
	VDBG_05120	RNA-binding protein. (748 aa)
	VDBG_05306	RING-2. (183 aa)
	VDBG_05375	Heat shock factor protein. (751 aa)
	VDBG_05547	Flocculation suppression protein. (529 aa)
	VDBG_05582	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (330 aa)
	VDBG_05852	Transcription initiation factor iif. (368 aa)
	VDBG_06033	Crossover junction endonuclease MUS81. (591 aa)
	VDBG_06626	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (262 aa)
	VDBG_06779	Curved DNA-binding protein. (388 aa)
	VDBG_06832	Cullin-4B; Belongs to the cullin family. (777 aa)
	VDBG_06876	Meiosis-specific transcription factor mei4. (747 aa)
	NIP1	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (872 aa)
	VDBG_09975	Forkhead domain-containing protein. (570 aa)
	VDBG_06974	FKH1. (379 aa)
	VDBG_07441	Lactamase_B domain-containing protein. (308 aa)
	VDBG_07674	ATP-dependent DNA helicase recQ. (677 aa)
	VDBG_08046	Vacuolar protein-sorting-associated protein. (161 aa)
	VDBG_08292	Replication factor-A protein. (181 aa)
	VDBG_08294	Serine/threonine-protein kinase RIO2. (416 aa)
	VDBG_08333	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (506 aa)
	VDBG_09796	Methyltransf_2 domain-containing protein. (471 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIP1	VDBG_00448	C9SPT7	C9S602	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	40S ribosomal protein S19.	0.988
NIP1	VDBG_03076	C9SPT7	C9SD02	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
NIP1	VDBG_06779	C9SPT7	C9SPF4	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Curved DNA-binding protein.	0.504
VDBG_00448	NIP1	C9S602	C9SPT7	40S ribosomal protein S19.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.988
VDBG_00448	VDBG_01165	C9S602	C9S5H9	40S ribosomal protein S19.	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.505
VDBG_00448	VDBG_01708	C9S602	C9SB49	40S ribosomal protein S19.	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.	0.505
VDBG_00448	VDBG_03076	C9S602	C9SD02	40S ribosomal protein S19.	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.968
VDBG_00448	VDBG_06779	C9S602	C9SPF4	40S ribosomal protein S19.	Curved DNA-binding protein.	0.868
VDBG_00448	VDBG_08294	C9S602	C9STM3	40S ribosomal protein S19.	Serine/threonine-protein kinase RIO2.	0.977
VDBG_01165	VDBG_00448	C9S5H9	C9S602	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	40S ribosomal protein S19.	0.505
VDBG_01503	VDBG_09966	C9SAB7	C9SYJ1	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.999
VDBG_01627	VDBG_08292	C9SAU4	C9STM1	zf-RING-like domain-containing protein.	Replication factor-A protein.	0.404
VDBG_01708	VDBG_00448	C9SB49	C9S602	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.	40S ribosomal protein S19.	0.505
VDBG_02265	VDBG_04362	C9S9U3	C9SJ91	26S proteasome regulatory subunit RPN5.	Cullin-1.	0.585
VDBG_02265	VDBG_04463	C9S9U3	C9SJJ2	26S proteasome regulatory subunit RPN5.	Anaphase-promoting complex subunit 2; Belongs to the cullin family.	0.638
VDBG_02265	VDBG_04809	C9S9U3	C9SIC7	26S proteasome regulatory subunit RPN5.	COP9 signalosome complex subunit 4.	0.588
VDBG_02265	VDBG_04858	C9S9U3	C9SIH6	26S proteasome regulatory subunit RPN5.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.811
VDBG_02265	VDBG_05035	C9S9U3	C9SJ03	26S proteasome regulatory subunit RPN5.	Cullin-3; Belongs to the cullin family.	0.585
VDBG_03076	NIP1	C9SD02	C9SPT7	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
VDBG_03076	VDBG_00448	C9SD02	C9S602	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	40S ribosomal protein S19.	0.968