(34 nodes) Pyruvate metabolism network (Verticillium alfalfae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	VDBG_01384	Acetyl-CoA hydrolase. (526 aa)
	VDBG_02271	Fumarate hydratase. (375 aa)
	VDBG_02377	D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (361 aa)
	VDBG_01542	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	VDBG_01777	Malate synthase; Belongs to the malate synthase family. (440 aa)
	VDBG_01915	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (372 aa)
	VDBG_02072	D-lactate dehydrogenase. (582 aa)
	VDBG_02828	D-lactate dehydrogenase. (501 aa)
	VDBG_02594	Aldehyde dehydrogenase. (377 aa)
	VDBG_03953	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (504 aa)
	VDBG_03977	Pyruvate kinase; Belongs to the pyruvate kinase family. (528 aa)
	VDBG_04044	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (442 aa)
	VDBG_04204	Cytochrome b2. (569 aa)
	VDBG_03737	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	VDBG_05024	Pyruvate carboxylase. (1073 aa)
	VDBG_04354	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	VDBG_05141	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (495 aa)
	VDBG_05150	Cytochrome b2; Belongs to the cytochrome b5 family. (411 aa)
	VDBG_05406	Acetyl-coenzyme A synthetase. (636 aa)
	VDBG_06142	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (618 aa)
	VDBG_07230	D-lactate dehydrogenase. (1182 aa)
	VDBG_07402	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (379 aa)
	VDBG_08010	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (324 aa)
	VDBG_08499	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (444 aa)
	VDBG_08589	Malate dehydrogenase. (335 aa)
	VDBG_08654	Malate dehydrogenase. (330 aa)
	VDBG_08696	Pyruvate dehydrogenase E1 component subunit alpha. (417 aa)
	VDBG_08711	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa)
	VDBG_09035	D-lactate dehydrogenase. (545 aa)
	VDBG_09038	Lactoylglutathione lyase. (254 aa)
	VDBG_09108	Cytochrome b2; Belongs to the cytochrome b5 family. (486 aa)
	VDBG_09176	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa)
	VDBG_09693	Dihydrolipoyl dehydrogenase. (508 aa)
	VDBG_09981	Malic enzyme. (603 aa)

Your Current Organism:

Verticillium alfalfae

NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VDBG_01384	VDBG_01542	C9S7Y5	C9SAI5	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.919
VDBG_01384	VDBG_01777	C9S7Y5	C9SBD4	Acetyl-CoA hydrolase.	Malate synthase; Belongs to the malate synthase family.	0.931
VDBG_01384	VDBG_02594	C9S7Y5	C9SE76	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase.	0.919
VDBG_01384	VDBG_03737	C9S7Y5	C9SH34	Acetyl-CoA hydrolase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.922
VDBG_01384	VDBG_03953	C9S7Y5	C9SF58	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.919
VDBG_01384	VDBG_04044	C9S7Y5	C9SFE9	Acetyl-CoA hydrolase.	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.914
VDBG_01384	VDBG_04354	C9S7Y5	C9SJ83	Acetyl-CoA hydrolase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.922
VDBG_01384	VDBG_05141	C9S7Y5	C9SK14	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.919
VDBG_01384	VDBG_05406	C9S7Y5	C9SKS9	Acetyl-CoA hydrolase.	Acetyl-coenzyme A synthetase.	0.939
VDBG_01384	VDBG_06142	C9S7Y5	C9SML8	Acetyl-CoA hydrolase.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.914
VDBG_01384	VDBG_07402	C9S7Y5	C9SR17	Acetyl-CoA hydrolase.	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.914
VDBG_01384	VDBG_08010	C9S7Y5	C9SSY5	Acetyl-CoA hydrolase.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.539
VDBG_01384	VDBG_08499	C9S7Y5	C9SU78	Acetyl-CoA hydrolase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.913
VDBG_01384	VDBG_08711	C9S7Y5	C9SUY6	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.919
VDBG_01384	VDBG_09038	C9S7Y5	C9SVW3	Acetyl-CoA hydrolase.	Lactoylglutathione lyase.	0.539
VDBG_01384	VDBG_09176	C9S7Y5	C9SWA1	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.919
VDBG_01542	VDBG_01384	C9SAI5	C9S7Y5	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetyl-CoA hydrolase.	0.919
VDBG_01542	VDBG_05406	C9SAI5	C9SKS9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase.	0.943
VDBG_01777	VDBG_01384	C9SBD4	C9S7Y5	Malate synthase; Belongs to the malate synthase family.	Acetyl-CoA hydrolase.	0.931
VDBG_01777	VDBG_02271	C9SBD4	C9S9U9	Malate synthase; Belongs to the malate synthase family.	Fumarate hydratase.	0.967