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ADH62086.1 ADH62086.1 ADH62087.1 ADH62087.1 ADH62651.1 ADH62651.1 ADH62652.1 ADH62652.1 ADH62731.1 ADH62731.1 ADH62732.1 ADH62732.1 ADH62753.1 ADH62753.1 ADH62754.1 ADH62754.1 ADH62842.1 ADH62842.1 ADH62843.1 ADH62843.1 ADH62941.1 ADH62941.1 ADH62971.1 ADH62971.1 ADH62972.1 ADH62972.1 ADH63003.1 ADH63003.1 ADH63005.1 ADH63005.1 ADH63290.1 ADH63290.1 ADH63291.1 ADH63291.1 ADH63726.1 ADH63726.1 ADH63964.1 ADH63964.1 ADH64646.1 ADH64646.1 ADH64814.1 ADH64814.1 ADH64818.1 ADH64818.1 ADH64819.1 ADH64819.1 ADH64825.1 ADH64825.1 ADH64826.1 ADH64826.1 ADH64970.1 ADH64970.1 ADH64971.1 ADH64971.1 ADH64972.1 ADH64972.1 ADH64973.1 ADH64973.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADH62086.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: ttj:TTHA1723 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XRT0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (365 aa)
ADH62087.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867; KEGG: ttj:TTHA1722 putative response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C1XRS9 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (221 aa)
ADH62651.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR009082:IPR 004358:IPR005467; KEGG: rpf:Rpic12D_4320 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XXE3 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (408 aa)
ADH62652.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR011991:IPR011006:IPR 016032; KEGG: dge:Dgeo_1522 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C1XFS8 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (223 aa)
ADH62731.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: dra:DR_1606 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XS74 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (413 aa)
ADH62732.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011991:IPR011006; KEGG: ttj:TTHA1002 response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C1XS75 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (217 aa)
ADH62753.1COGs: COG5002 Signal transduction histidine kinase; InterProIPR009082:IPR000014:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: ttj:TTHA0144 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C1XS96 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (345 aa)
ADH62754.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR011991:IPR011006:IPR 016032; KEGG: ttj:TTHA0145 phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C1XS97 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (223 aa)
ADH62842.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: ava:Ava_3779 CheA signal transduction histidine kinases (STHK); PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: C1XSI8 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (125 aa)
ADH62843.1COGs: COG5002 Signal transduction histidine kinase; InterProIPR009082:IPR013656:IPR000014:IPR003594:IPR 003661:IPR005467:IPR003018:IPR004358; KEGG: tth:TTC0778 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; GAF domain protein; SPTR: C1XSI9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hi [...] (827 aa)
ADH62941.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: ttj:TTHA1002 response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1XXH5 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (227 aa)
ADH62971.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867; KEGG: dge:Dgeo_1522 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C1XXE4 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (222 aa)
ADH62972.1COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR009082:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: dge:Dgeo_1521 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: C1XXE3 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Ki [...] (425 aa)
ADH63003.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: ttj:TTHA1363 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XXB2 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (442 aa)
ADH63005.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR001789:IPR011991:IPR011006; KEGG: ttj:TTHA1362 response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1XXA9 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (224 aa)
ADH63290.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867; KEGG: tth:TTC1229 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C1XW03 Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (219 aa)
ADH63291.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003594:IPR003661:IPR005467:IPR 004358; KEGG: ttj:TTHA1592 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C1XW02 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (457 aa)
ADH63726.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR004942:IPR011006; KEGG: dra:DR_A0357 response regulator; PFAM: response regulator receiver; Roadblock/LC7 family protein; SMART: response regulator receiver; SPTR: C1XT05 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (263 aa)
ADH63964.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006:IPR013670; KEGG: ddr:Deide_08380 putative response regulator, CheY; PFAM: response regulator receiver; EcoEI R domain protein; SMART: response regulator receiver; SPTR: C1XQL0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; EcoEI R protein C-terminal. (298 aa)
ADH64646.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR001789:IPR011991:IPR011006; KEGG: ttj:TTHA1722 putative response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1XTV0 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (219 aa)
ADH64814.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: gym:GYMC10_5092 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: C1XV43 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (133 aa)
ADH64818.1COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006; KEGG: ddr:Deide_2p00600 putative response regulator, CheY; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: C1XV39 Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Response regulator receiver domain. (138 aa)
ADH64819.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR000700:IPR009082:IPR001610:IPR003594:IPR 003661:IPR005467:IPR013655:IPR004358; KEGG: rca:Rcas_3032 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: C1XV38 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; T [...] (384 aa)
ADH64825.1Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003661:IPR003594:IPR004358:IPR009082:IPR 005467; KEGG: gem:GM21_2941 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C1XV32 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (410 aa)
ADH64826.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR001789:IPR011006:IPR016032; KEGG: phe:Phep_3446 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1XV31 Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Response regulator receiver domain; Transcriptional reg [...] (256 aa)
ADH64970.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR004358:IPR009082:IPR003660:IPR 003661:IPR005467; KEGG: dge:Dgeo_2750 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XYD2 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) [...] (436 aa)
ADH64971.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR001789:IPR011991:IPR011006; KEGG: dge:Dgeo_2749 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1XYD1 Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Response regulator receiver domain; Transcr [...] (226 aa)
ADH64972.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: fal:FRAAL3820 putative transmembrane sensory transduction histidine kinase for metal resistance; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XYD0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His K [...] (439 aa)
ADH64973.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: azc:AZC_1953 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1XYC9 Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Response regulator receiver domain; Transcriptional regulatory pro [...] (218 aa)
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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