STRINGSTRING
ADH64464.1 ADH64464.1 ADH64487.1 ADH64487.1 proB proB ADH64550.1 ADH64550.1 ADH64561.1 ADH64561.1 ADH64581.1 ADH64581.1 ADH64691.1 ADH64691.1 ADH64700.1 ADH64700.1 ADH64708.1 ADH64708.1 argB argB adk adk ADH64812.1 ADH64812.1 ADH64819.1 ADH64819.1 ADH64825.1 ADH64825.1 ADH64833.1 ADH64833.1 ADH64866.1 ADH64866.1 ADH64887.1 ADH64887.1 xylB-2 xylB-2 xylB-3 xylB-3 pfkA-2 pfkA-2 ADH64940.1 ADH64940.1 ADH64956.1 ADH64956.1 ADH64970.1 ADH64970.1 ADH64972.1 ADH64972.1 ADH61952.1 ADH61952.1 ADH62011.1 ADH62011.1 cmk cmk ndk ndk ADH62073.1 ADH62073.1 ADH62086.1 ADH62086.1 pfkA pfkA rbsK rbsK ADH62180.1 ADH62180.1 ADH62234.1 ADH62234.1 ADH62290.1 ADH62290.1 coaX coaX ADH62307.1 ADH62307.1 ADH62312.1 ADH62312.1 ADH62318.1 ADH62318.1 lysZ lysZ ADH62415.1 ADH62415.1 ADH62534.1 ADH62534.1 ADH62610.1 ADH62610.1 xylB xylB ADH62651.1 ADH62651.1 ADH62677.1 ADH62677.1 ADH62688.1 ADH62688.1 ADH62731.1 ADH62731.1 ADH62753.1 ADH62753.1 ispE ispE ADH62840.1 ADH62840.1 ADH62843.1 ADH62843.1 thrB thrB ADH62875.1 ADH62875.1 ADH62891.1 ADH62891.1 ADH62905.1 ADH62905.1 ADH62906.1 ADH62906.1 ADH62926.1 ADH62926.1 glpK glpK ADH62955.1 ADH62955.1 ADH62972.1 ADH62972.1 ADH62998.1 ADH62998.1 ADH63003.1 ADH63003.1 ADH63007.1 ADH63007.1 ADH63032.1 ADH63032.1 ADH63139.1 ADH63139.1 ADH63184.1 ADH63184.1 ADH63205.1 ADH63205.1 gmk gmk aroK aroK ADH63246.1 ADH63246.1 ADH63268.1 ADH63268.1 ADH63276.1 ADH63276.1 ADH63282.1 ADH63282.1 ADH63291.1 ADH63291.1 ADH63318.1 ADH63318.1 ADH63335.1 ADH63335.1 ADH63535.1 ADH63535.1 ADH63540.1 ADH63540.1 ADH63594.1 ADH63594.1 ADH63698.1 ADH63698.1 ADH63719.1 ADH63719.1 pyrH pyrH ADH63843.1 ADH63843.1 ackA ackA ADH63875.1 ADH63875.1 pgk pgk ADH63987.1 ADH63987.1 udk udk tdk tdk coaE coaE ADH64100.1 ADH64100.1 ADH64229.1 ADH64229.1 ADH64253.1 ADH64253.1 ADH64306.1 ADH64306.1 ADH64307.1 ADH64307.1 tmk tmk anmK anmK ADH64447.1 ADH64447.1 ADH64475.1 ADH64475.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADH64464.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002139:IPR002173; KEGG: ttj:TTHA0431 sugar kinase; PFAM: PfkB domain protein; SPTR: C1XP25 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (305 aa)
ADH64487.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: tth:TTC1139 two-component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XP02 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (475 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (383 aa)
ADH64550.1COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358:IPR011712; KEGG: ttj:TTHA1181 sensor histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; SPTR: C1XU56 Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (552 aa)
ADH64561.1Lipopolysaccharide biosynthesis protein; InterPro IPR003856; KEGG: tth:TTC0274 hypothetical protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: C1XU43 Chain length determinant protein; PFAM: Chain length determinant protein. (341 aa)
ADH64581.1Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: ttj:TTHA1637 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: C1XU23 Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. (308 aa)
ADH64691.1COGs: COG4585 Signal transduction histidine kinase; InterProIPR000014:IPR003018:IPR003594:IPR013767:IPR 011712:IPR005467; KEGG: rca:Rcas_4226 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; PAS fold domain protein; PRIAM: Histidine kinase; SMART: GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein; SPTR: C1XTQ5 PAS domain S-box protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase; GAF domain; Histidi [...] (682 aa)
ADH64700.1Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: ddr:Deide_3p01560 putative rhamnulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: C1XTP6 Pentulose/hexulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: rhamnulokinase. (516 aa)
ADH64708.1COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR017442:IPR017441:IPR 008271:IPR011009:IPR000719; KEGG: dra:DR_A0332 protein kinase, putative; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: C1XTM2 Serine/threonine protein kinase; PFAM: Protein kinase domain. (615 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (276 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (183 aa)
ADH64812.1ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ttj:TTHA0299 glucokinase; PFAM: ROK family protein; SPTR: C1XV45 Glucokinase; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (300 aa)
ADH64819.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR000700:IPR009082:IPR001610:IPR003594:IPR 003661:IPR005467:IPR013655:IPR004358; KEGG: rca:Rcas_3032 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: C1XV38 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; T [...] (384 aa)
ADH64825.1Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003661:IPR003594:IPR004358:IPR009082:IPR 005467; KEGG: gem:GM21_2941 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C1XV32 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (410 aa)
ADH64833.1DAK2 domain fusion protein YloV; COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR004007:IPR019986; KEGG: ttj:TTHA0214 kinase; PFAM: Dak phosphatase; SPTR: C1XV24 Predicted kinase, dihydroxyacetone kinase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV. (533 aa)
ADH64866.1Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR005218:IPR001206; KEGG: tth:TTC1957 protein BmrU; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: C1XUZ0 Putative uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: conserved protein of unknown function cotranscribed with Bmr (bmrU). (292 aa)
ADH64887.1Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR018485:IPR018484; KEGG: dge:Dgeo_2863 carbohydrate kinase, FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: C1XUW7 Pentulose/hexulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; Belongs to the FGGY kinase family. (505 aa)
xylB-2Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR006000:IPR018485:IPR018484; KEGG: rxy:Rxyl_0402 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: C1XUW6 Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase. (511 aa)
xylB-3Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR006000:IPR018485:IPR018484; KEGG: rxy:Rxyl_2898 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: C1XUV4 D-xylulose kinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase. (472 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (322 aa)
ADH64940.1LAO/AO transport system ATPase; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: ttj:TTHA0136 LAO/AO transport system kinase; PFAM: ArgK protein; SPTR: C1XYH1 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase. (304 aa)
ADH64956.1COGs: COG3603 conserved hypothetical protein; InterPro IPR016540; KEGG: atc:AGR_C_1340 hypothetical protein; SPTR: C1XYF4 Uncharacterized conserved protein. (134 aa)
ADH64970.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR004358:IPR009082:IPR003660:IPR 003661:IPR005467; KEGG: dge:Dgeo_2750 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XYD2 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) [...] (436 aa)
ADH64972.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: fal:FRAAL3820 putative transmembrane sensory transduction histidine kinase for metal resistance; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XYD0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His K [...] (439 aa)
ADH61952.1COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR011037:IPR015793:IPR 015794:IPR001697:IPR018209; KEGG: ttj:TTHA0003 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: C1XVA7 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
ADH62011.1COGs: COG4585 Signal transduction histidine kinase; InterProIPR003594:IPR003018:IPR011712:IPR005467:IPR 004358; KEGG: bcl:ABC3141 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: C1XS12 Histidine kinase with GAF domain; PFAM: Histidine kinase; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (396 aa)
cmkCOGs: COG0283 Cytidylate kinase; InterPro IPR011994:IPR003136; KEGG: ttj:TTHA0458 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: C1XRU9 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. (222 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa)
ADH62073.1COGs: COG0515 Serine/threonine protein kinase; InterProIPR011009:IPR011047:IPR020635:IPR002290:IPR 018391:IPR000719:IPR017442:IPR002372:IPR017441:IPR008266; KEGG: ttj:TTHA0138 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; Pyrrolo-quinoline quinone; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; Pyrrolo-quinoline quinone beta-propeller repeat; SPTR: C1XRU4 Serine/threonine protein kinase; PFAM: Protein kinase domain; PQQ enzyme repeat. (611 aa)
ADH62086.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: ttj:TTHA1723 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XRT0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (365 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa)
ADH62180.1COGs: COG2605 kinase related to galactokinase and mevalonate kinase; InterProIPR020568:IPR006204:IPR013750:IPR014721:IPR 014606:IPR001174; KEGG: cac:CAC3055 sugar kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: C1XRI1 Predicted kinase, galactokinase/mevalonate kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain. (350 aa)
ADH62234.1ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: sth:STH292 hypothetical protein; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: C1XRC5 Predicted N-acetylglucosamine kinase; PFAM: BadF/BadG/BcrA/BcrD ATPase family. (335 aa)
ADH62290.1COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: ttj:TTHA1749 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (FolK); PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: C1XR66 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydro [...] (175 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
ADH62307.1Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004399; KEGG: ttj:TTHA0680 phosphomethylpyrimidine kinase (ThiD); PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: C1XR49 Hydroxymethylpyrimidine kinase; phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (266 aa)
ADH62312.1PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ttj:TTHA0371 serine/threonine-protein kinase; PFAM: PASTA domain containing protein; SMART: PASTA domain containing protein; SPTR: C1XR44 Uncharacterized conserved protein; PFAM: PASTA domain. (530 aa)
ADH62318.1(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (738 aa)
lysZAcetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily. (269 aa)
ADH62415.1KEGG: tth:TTC1474 putative cytoplasmic protein; SPTR: C1XY64 Putative uncharacterized protein. (240 aa)
ADH62534.1Fumble domain protein; COGs: COG5146 Pantothenate kinase acetyl-CoA regulated; InterPro IPR008040:IPR011602; KEGG: gau:GAU_3146 hypothetical protein; PFAM: Fumble domain protein; Hydantoinaseoxoprolinase domain protein; SPTR: C1XWJ5 Pantothenate kinase, acetyl-CoA regulated; PFAM: Fumble; TIGRFAM: pantothenate kinase, eukaryotic/staphyloccocal type. (278 aa)
ADH62610.1ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600:IPR000835; KEGG: ttr:Tter_2656 ROK family protein; PFAM: ROK family protein; regulatory protein MarR; SPTR: C1XWA4 Transcriptional regulator, MarR family; PFAM: ROK family; MarR family. (382 aa)
xylBXylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR006000:IPR018485:IPR018484; KEGG: dge:Dgeo_2691 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: C1XWA1 Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase. (499 aa)
ADH62651.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR009082:IPR 004358:IPR005467; KEGG: rpf:Rpic12D_4320 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XXE3 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (408 aa)
ADH62677.1Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946:IPR000842; KEGG: ttj:TTHA1549 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: C1XSR2 Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. (361 aa)
ADH62688.1Fructosamine/Ketosamine-3-kinase; COGs: COG3001 conserved hypothetical protein; InterPro IPR016477:IPR011009; KEGG: tth:TTC0815 phosphatidylserine decarboxylase; PFAM: Fructosamine/Ketosamine-3-kinase; SPTR: C1XSS3 Fructosamine-3-kinase; PFAM: Fructosamine kinase. (266 aa)
ADH62731.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: dra:DR_1606 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XS74 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (413 aa)
ADH62753.1COGs: COG5002 Signal transduction histidine kinase; InterProIPR009082:IPR000014:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: ttj:TTHA0144 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C1XS96 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (345 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (275 aa)
ADH62840.1COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371:IPR006282; KEGG: bbk:BARBAKC583_0128 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; SPTR: C1XSI6 Thiamine pyrophosphokinase; TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase. (211 aa)
ADH62843.1COGs: COG5002 Signal transduction histidine kinase; InterProIPR009082:IPR013656:IPR000014:IPR003594:IPR 003661:IPR005467:IPR003018:IPR004358; KEGG: tth:TTC0778 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; GAF domain protein; SPTR: C1XSI9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hi [...] (827 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (290 aa)
ADH62875.1COGs: COG3231 Aminoglycoside phosphotransferase; InterPro IPR011009:IPR002575; KEGG: ret:RHE_CH02947 putative aminoglycoside 3'-phosphotransferase protein; PFAM: aminoglycoside phosphotransferase; SPTR: C1XSM4 Aminoglycoside phosphotransferase; PFAM: Phosphotransferase enzyme family; Belongs to the aminoglycoside phosphotransferase family. (270 aa)
ADH62891.1Carbohydrate kinase, thermoresistant glucokinase family; COGs: COG3265 Gluconate kinase; InterPro IPR006001:IPR000623; KEGG: mxa:MXAN_0616 thermosensitive gluconokinase; PFAM: shikimate kinase; SPTR: C1XSP1 Gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family. (165 aa)
ADH62905.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (787 aa)
ADH62906.1Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (273 aa)
ADH62926.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: rsp:RSP_4029 carbohydrate kinase, PfkB; PFAM: PfkB domain protein; SPTR: C1XXJ4 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (284 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (496 aa)
ADH62955.1COGs: COG4585 Signal transduction histidine kinase; InterProIPR003594:IPR017205:IPR011712:IPR005467:IPR 004358; KEGG: sti:Sthe_1551 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; SPTR: C1XXG1 Signal transduction histidine kinase, COG4585; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (490 aa)
ADH62972.1COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR009082:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: dge:Dgeo_1521 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: C1XXE3 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Ki [...] (425 aa)
ADH62998.1COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: ttj:TTHA0634 magnesium chelatase related protein; SPTR: C1XXB7 Mg-chelatase subunit ChlI. (473 aa)
ADH63003.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR003594:IPR003661:IPR 005467:IPR004358; KEGG: ttj:TTHA1363 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C1XXB2 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (442 aa)
ADH63007.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: dth:DICTH_0637 ribokinase:carbohydrate kinase, PfkB; PFAM: PfkB domain protein; SPTR: C1XXA7 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (306 aa)
ADH63032.1KEGG: ttj:TTHA0330 hypothetical protein; SPTR: C1XX80 Putative uncharacterized protein. (197 aa)
ADH63139.1COGs: COG0855 Polyphosphate kinase; InterPro IPR003414; KEGG: tth:TTC0637 polyphosphate kinase; PFAM: Polyphosphate kinase; PRIAM: Polyphosphate kinase; SPTR: C1XXV5 Polyphosphate kinase; PFAM: Polyphosphate kinase. (620 aa)
ADH63184.1Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: ddr:Deide_3p00052 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: C1XXQ9 Uncharacterized conserved protein; PFAM: Uncharacterised protein family (UPF0157). (375 aa)
ADH63205.1Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR005829:IPR001206; KEGG: ddr:Deide_04630 putative diacylglycerol kinase; PFAM: diacylglycerol kinase catalytic region; SPTR: C1XXN7 Sphingosine/diacylglycerol kinase-like enzyme; PFAM: Diacylglycerol kinase catalytic domain. (318 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (224 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (219 aa)
ADH63246.1ATP-cone domain protein; COGs: COG2074 2-phosphoglycerate kinase; InterPro IPR005144; KEGG: tth:TTC0121 2-phosphoglycerate kinase; PFAM: ATP-cone domain protein; SPTR: C1XW50 2-phosphoglycerate kinase; PFAM: ATP cone domain. (477 aa)
ADH63268.1KEGG: ttj:TTHA1604 hypothetical protein; SPTR: C1XW25 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3467). (89 aa)
ADH63276.1COGs: COG0515 Serine/threonine protein kinase; InterProIPR008271:IPR011009:IPR011042:IPR017442:IPR 000719:IPR017441:IPR013017:IPR001258; KEGG: ttj:TTHA1594 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; NHL repeat containing protein; SPTR: C1XW17 Serine/threonine protein kinase; PFAM: Protein kinase domain. (678 aa)
ADH63282.1KEGG: ttj:TTHB089 hypothetical protein; SPTR: C1XW11 Putative uncharacterized protein; PFAM: Alginate O-acetyl transferase AlgF. (232 aa)
ADH63291.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003594:IPR003661:IPR005467:IPR 004358; KEGG: ttj:TTHA1592 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C1XW02 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (457 aa)
ADH63318.1Hydroxypyruvate reductase; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: dge:Dgeo_2615 hydroxypyruvate reductase; PFAM: MOFRL domain protein; PRIAM: Hydroxypyruvate reductase; SPTR: C1XVX6 Glycerate 2-kinase; PFAM: MOFRL family. (424 aa)
ADH63335.1COGs: COG0515 Serine/threonine protein kinase; InterPro IPR011009:IPR017442:IPR000719:IPR017441; KEGG: tth:TTC0918 protein kinase-like protein; PFAM: Serine/threonine-protein kinase-like domain; SPTR: C1XVV9 Protein kinase family protein; PFAM: Protein kinase domain. (286 aa)
ADH63535.1Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR004821:IPR015864:IPR002606; KEGG: ttj:TTHA0527 riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; SMART: Riboflavin kinase; SPTR: C1XUB0 FMN adenylyltransferase; riboflavin kinase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. (296 aa)
ADH63540.1COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR000719:IPR017442:IPR 008271:IPR011009; KEGG: ttj:TTHA1370 serine/threonine-protein kinase-related protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: C1XUA5 Protein kinase family protein; PFAM: Protein kinase domain. (260 aa)
ADH63594.1COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR018042:IPR002912:IPR 005260; KEGG: ttj:TTHA0534 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; PRIAM: Aspartate kinase; SPTR: C1XYW0 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (406 aa)
ADH63698.1Putative serine protein kinase, PrkA; COGs: COG2766 Putative Ser protein kinase; InterPro IPR013153:IPR010650; KEGG: ttj:TTHA0843 serine protein kinase; PFAM: PrkA AAA domain protein; PrkA serine kinase; SMART: PrkA AAA domain protein; SPTR: C1XT75 Putative Ser protein kinase; PFAM: PrkA AAA domain; PrkA serine protein kinase C-terminal domain. (709 aa)
ADH63719.1COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: dra:DR_A0350 response regulator PilH, putative; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: C1XT12 Response regulator containing a CheY-like receiver domain and a GGDEF domain; PFAM: Response regulator receiver domain. (122 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa)
ADH63843.1Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: dra:DR_1363 hypothetical protein; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: C1XT30 Sphingosine/diacylglycerol kinase-like enzyme; PFAM: Diacylglycerol kinase catalytic domain. (334 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (336 aa)
ADH63875.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: dra:DR_2553 carbohydrate kinase, putative; PFAM: PfkB domain protein; SPTR: C1XQV0 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (321 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015901:IPR015911:IPR015824; KEGG: pzu:PHZ_p0042 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: C1XQP2 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
ADH63987.1InterPro IPR011009:IPR002575; KEGG: cce:Ccel_1212 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: C1XQI5 Putative homoserine kinase type II (Protein kinase fold); PFAM: Phosphotransferase enzyme family; TIGRFAM: Fibrobacter succinogenes paralogous family TIGR02172. (273 aa)
udkCOGs: COG0572 Uridine kinase; InterPro IPR017975:IPR006083:IPR000764:IPR003593; KEGG: ttj:TTHA0578 uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase; SPTR: C1XQ96 Uridine kinase; TIGRFAM: uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase. (223 aa)
tdkCOGs: COG1435 Thymidine kinase; InterPro IPR020633:IPR001267; KEGG: dge:Dgeo_0578 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: C1XQ88 Thymidine kinase; PFAM: Thymidine kinase. (203 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa)
ADH64100.1COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: ttj:TTHA1044 diacylglycerol kinase; PFAM: diacylglycerol kinase; SPTR: C1XJH3 Diacylglycerol kinase; PFAM: Prokaryotic diacylglycerol kinase. (131 aa)
ADH64229.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003594:IPR009082:IPR 003661:IPR004358; KEGG: tth:TTC0388 sensory transduction protein kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C1XPS0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (336 aa)
ADH64253.1Galactokinase; COGs: COG0153 Galactokinase; InterProIPR013750:IPR020568:IPR000705:IPR006204:IPR 006206:IPR014721:IPR019539:IPR006203; KEGG: tth:TTC0226 galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; Galactokinase galactose-binding domain; SPTR: C1XPP6 Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily. (349 aa)
ADH64306.1COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: dra:DR_0299 deoxyguanosine kinase/deoxyadenosine kinase subunit; PFAM: deoxynucleoside kinase; SPTR: C1XPJ0 Deoxynucleoside kinase; PFAM: Deoxynucleoside kinase. (205 aa)
ADH64307.1COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: dra:DR_0298 deoxyguanosine kinase/deoxyadenosine kinase subunit; PFAM: deoxynucleoside kinase; SPTR: C1XPI9 Deoxynucleoside kinase; PFAM: Deoxynucleoside kinase. (214 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (202 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (359 aa)
ADH64447.1ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: aha:AHA_3099 N-acetylglucosamine kinase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: C1XP43 Predicted N-acetylglucosamine kinase; PFAM: BadF/BadG/BcrA/BcrD ATPase family. (295 aa)
ADH64475.1Protein of unknown function DUF344; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660:IPR016898; KEGG: aba:Acid345_0575 polyphosphate:AMP phosphotransferase; PFAM: protein of unknown function DUF344; SPTR: C1XP14 Polyphosphate:AMP phosphotransferase; PFAM: Polyphosphate kinase 2 (PPK2). (268 aa)
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.