STRINGSTRING
ADH63279.1 ADH63279.1 eno eno ADH62016.1 ADH62016.1 nth nth dacA dacA ADH62152.1 ADH62152.1 ADH62159.1 ADH62159.1 mltG mltG ADH62200.1 ADH62200.1 ADH62252.1 ADH62252.1 lysA lysA ADH62263.1 ADH62263.1 trpE trpE ADH62297.1 ADH62297.1 ADH62301.1 ADH62301.1 thiC thiC leuD leuD leuC leuC pckG pckG ADH62595.1 ADH62595.1 ADH62641.1 ADH62641.1 ADH62672.1 ADH62672.1 luxS luxS psuG psuG ADH62736.1 ADH62736.1 fabZ fabZ ubiX ubiX ADH62813.1 ADH62813.1 moaC moaC nnrD nnrD ADH62916.1 ADH62916.1 ADH62918.1 ADH62918.1 ADH62919.1 ADH62919.1 ADH62927.1 ADH62927.1 ADH62963.1 ADH62963.1 ispF ispF ADH62992.1 ADH62992.1 ADH63008.1 ADH63008.1 mgsA mgsA ADH63144.1 ADH63144.1 ADH63164.1 ADH63164.1 ADH63183.1 ADH63183.1 purK purK ADH63222.1 ADH63222.1 aroC aroC ADH63253.1 ADH63253.1 ADH63327.1 ADH63327.1 mutM mutM ADH63380.1 ADH63380.1 mqnA mqnA ilvD ilvD ADH63489.1 ADH63489.1 leuC-2 leuC-2 hutU hutU hutH hutH ppc ppc ADH63590.1 ADH63590.1 ADH63592.1 ADH63592.1 ADH63658.1 ADH63658.1 menC menC ADH63709.1 ADH63709.1 trpB trpB trpA trpA ADH63736.1 ADH63736.1 ADH63750.1 ADH63750.1 ADH63762.1 ADH63762.1 ADH63817.1 ADH63817.1 ADH63862.1 ADH63862.1 rlpA rlpA tal tal pdxS pdxS pdxT pdxT ADH63943.1 ADH63943.1 ADH63963.1 ADH63963.1 ADH63998.1 ADH63998.1 fumC fumC ADH64026.1 ADH64026.1 hisF hisF ADH64104.1 ADH64104.1 ADH64133.1 ADH64133.1 dapA dapA ADH64168.1 ADH64168.1 ADH64211.1 ADH64211.1 argH argH ADH64283.1 ADH64283.1 ADH64316.1 ADH64316.1 aroQ aroQ ADH64395.1 ADH64395.1 ADH64440.1 ADH64440.1 deoC deoC hisH hisH hisB hisB pyrF pyrF ADH64596.1 ADH64596.1 ADH64658.1 ADH64658.1 mqnD mqnD deoC-2 deoC-2 ADH64823.1 ADH64823.1 ADH64824.1 ADH64824.1 hemE hemE hemH hemH ADH64909.1 ADH64909.1 speA speA ADH64980.1 ADH64980.1 ADH65009.1 ADH65009.1
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ADH63279.1COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR006050:IPR005101:IPR002081:IPR014729; KEGG: tth:TT_P0058 deoxyribodipyrimidine photolyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; PRIAM: Deoxyribodipyrimidine photo-lyase; SPTR: C1XW14 Deoxyribodipyrimidine photo-lyase type I; PFAM: FAD binding domain of DNA photolyase; DNA photolyase. (435 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
ADH62016.1COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR002912:IPR005789; KEGG: cag:Cagg_0043 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: C1XS07 L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. (410 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (237 aa)
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (239 aa)
ADH62152.1Tetratricopeptide TPR_4; COGs: COG3899 ATPase; InterPro IPR011990:IPR019734:IPR011717:IPR013026; KEGG: ddr:Deide_1p00540 hypothetical protein; PFAM: Tetratricopeptide TPR_4; SPTR: C1XRK8 Putative uncharacterized protein; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type. (1042 aa)
ADH62159.1Transcriptional activator domain protein; COGs: COG3899 ATPase; InterProIPR003593:IPR019734:IPR013026:IPR005158:IPR 001440:IPR011717:IPR011990; KEGG: ddr:Deide_15610 putative transcriptional regulator, AfsR/DnrI/RedD family; PFAM: transcriptional activator domain; TPR repeat-containing protein; Tetratricopeptide TPR_4; SMART: AAA ATPase; Tetratricopeptide repeat; SPTR: C1XRK1 Putative transcriptional regulator; PFAM: Archaeal ATPase; Bacterial transcriptional activator domain. (1163 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (322 aa)
ADH62200.1TPR repeat-containing protein; COGs: COG3899 ATPase; InterProIPR001054:IPR019734:IPR013026:IPR001440:IPR 011990; KEGG: hau:Haur_1458 adenylate/guanylate cyclase; PFAM: TPR repeat-containing protein; SPTR: C1XRG0 Predicted ATPase, COG3899; PFAM: Adenylate and Guanylate cyclase catalytic domain. (1298 aa)
ADH62252.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (394 aa)
ADH62263.1COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; InterPro IPR017443:IPR000685; KEGG: rpe:RPE_3678 rubisco-like protein Rlp1; PFAM: ribulose bisphosphate carboxylase large chain; SPTR: C1XR93 Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain. (363 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (469 aa)
ADH62297.1UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: ttj:TTHA0373 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; PFAM: Carboxylyase-related protein; SPTR: C1XR59 3-octaprenyl-4hydroxybenzoate decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. (606 aa)
ADH62301.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (436 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (166 aa)
leuC3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (423 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (632 aa)
ADH62595.1VanZ family protein; InterPro IPR006976; KEGG: ttj:TTHA0393 hypothetical protein; PFAM: VanZ family protein; SPTR: C1XWC1 Predicted integral membrane protein, COG5652; PFAM: VanZ like family. (109 aa)
ADH62641.1Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (324 aa)
ADH62672.1Fructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289:IPR013785; KEGG: ttj:TTHA1773 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: C1XSQ7 Fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. (305 aa)
luxSQuorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (158 aa)
psuGIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (305 aa)
ADH62736.1Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: ttj:TTHA1811 fuculose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: C1XS79 Ribulose-5-phosphate 4-epimerase-like epimerase or aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain. (196 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (142 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (192 aa)
ADH62813.1Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: tth:TTC0412 L-ribulose-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; SPTR: C1XIU5 Ribulose-5-phosphate 4-epimerase-like epimerase or aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain. (357 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)
nnrDCarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (479 aa)
ADH62916.1COGs: COG2224 Isocitrate lyase; InterPro IPR006254:IPR018523:IPR000918:IPR015813; KEGG: ttj:TTHA1836 isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; SPTR: C1XZ89 Isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase. (429 aa)
ADH62918.1SAF domain protein; InterPro IPR013974; KEGG: tac:Ta1392 hypothetical protein; PFAM: SAF domain protein; SPTR: C1XXK2 Altronate dehydratase; PFAM: SAF domain. (107 aa)
ADH62919.1D-galactarate dehydratase/Altronate hydrolase domain protein; COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: rxy:Rxyl_2590 D-galactarate dehydratase/altronate hydrolase-like protein; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SPTR: C1XXK1 Altronate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus. (390 aa)
ADH62927.1COGs: COG3684 Tagatose-1 6-bisphosphate aldolase; InterPro IPR013785:IPR002915; KEGG: bja:bll6350 tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Tagatose-bisphosphate aldolase; SPTR: C1XXJ3 Tagatose-1,6-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase. (329 aa)
ADH62963.1COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR003031:IPR008948:IPR020557:IPR 019468:IPR004769; KEGG: tth:TTC1149 putative adenylosuccinate lyase protein; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: C1XXF2 Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (436 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (167 aa)
ADH62992.1COGs: COG0031 Cysteine synthase; InterProIPR005856:IPR001926:IPR000634:IPR001216:IPR 005859; KEGG: tth:TTC1636 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: C1XXC3 Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa)
ADH63008.1Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR018225:IPR013785; KEGG: amr:AM1_1655 transaldolase, putative; PFAM: Transaldolase; SPTR: C1XXA6 Transaldolase; PFAM: Transaldolase; TIGRFAM: transaldolase, putative, TalC family. (217 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (128 aa)
ADH63144.1COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376:IPR001753; KEGG: tth:TTC0182 enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C1XXV0 Enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
ADH63164.1Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterProIPR010954:IPR020822:IPR006268:IPR006218:IPR 013785:IPR002701; KEGG: ttj:TTHA0388 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SMART: Chorismate mutase; SPTR: C1XXT0 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; chorismate mutase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; chorismate mutase; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: cho [...] (358 aa)
ADH63183.1COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015422:IPR015421; KEGG: tro:trd_A0675 methionine gamma-lyase (L-methioninase); PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cystathionine gamma-lyase; SPTR: C1XXR0 Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (388 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa)
ADH63222.1COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658:IPR016303; KEGG: tth:TTC1020 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: C1XXL8 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase. (351 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (383 aa)
ADH63253.1COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: rmr:Rmar_1263 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: C1XW42 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (428 aa)
ADH63327.1S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine. (146 aa)
mutMformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (274 aa)
ADH63380.1Protein of unknown function DUF422; COGs: COG2324 membrane protein; InterPro IPR007354; KEGG: ddr:Deide_2p01210 hypothetical protein; putative membrane protein; PFAM: protein of unknown function DUF422; SPTR: C1XVQ9 Predicted membrane protein, COG2324; PFAM: Protein of unknown function (DUF422). (397 aa)
mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (271 aa)
ilvDCOGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR020558:IPR004404; KEGG: ttj:TTHA1234 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C1XUG4 Dihydroxyacid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (554 aa)
ADH63489.13-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuC-23-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (547 aa)
hutHCOGs: COG2986 Histidine ammonia-lyase; InterPro IPR008948:IPR001106:IPR005921; KEGG: dge:Dgeo_2730 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: C1XUC3 Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase. (506 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (892 aa)
ADH63590.1COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753:IPR018376; KEGG: tth:TTC1697 enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C1XYW4 Short chain enoyl-CoA hydratase; Enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
ADH63592.1COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376:IPR001753; KEGG: ara:Arad_0598 enoyl-CoA hydratase protein; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C1XYW2 Short chain enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
ADH63658.1OHCU decarboxylase; COGs: COG3195 conserved hypothetical protein; InterPro IPR017580:IPR018020; KEGG: sus:Acid_0358 hypothetical protein; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: C1XTH4 OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; PFAM: OHCU decarboxylase; TIGRFAM: OHCU decarboxylase. (167 aa)
menCO-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (372 aa)
ADH63709.1COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (475 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (417 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)
ADH63736.1S-adenosylmethionine decarboxylase related protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine. (144 aa)
ADH63750.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (217 aa)
ADH63762.1Protein of unknown function DUF2006; COGs: COG5621 secreted hydrolase; InterPro IPR018549; KEGG: ttj:TTHA0993 hypothetical protein; PFAM: Protein of unknown function DUF2006; SPTR: C1XTG0 Predicted secreted hydrolase; PFAM: Hydroxyneurosporene synthase (CrtC). (341 aa)
ADH63817.1Transcriptional coactivator/pterin dehydratase; COGs: COG2154 Pterin-4a-carbinolamine dehydratase; InterPro IPR001533; KEGG: scl:sce1698 putative pterin-4-alpha-carbinolamine dehydratase; PFAM: transcriptional coactivator/pterin dehydratase; SPTR: C1XT58 Pterin-4a-carbinolamine dehydratase; PFAM: Pterin 4 alpha carbinolamine dehydratase. (98 aa)
ADH63862.1COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterProIPR015422:IPR015424:IPR000277:IPR006235:IPR 015421; KEGG: ttj:TTHA0760 O-acetyl-L-homoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: O-acetylhomoserine aminocarboxypropyltransferase; SPTR: C1XSW2 O-acetylhomoserine sulfhydrolase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (434 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (168 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (219 aa)
pdxSPyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (303 aa)
pdxTSNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (190 aa)
ADH63943.1COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376:IPR001753; KEGG: ttj:TTHA1434 3-hydroxybutyryl-CoA dehydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C1XQN1 Short chain enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa)
ADH63963.1Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. (280 aa)
ADH63998.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
ADH64026.1COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR013785:IPR011060:IPR001468; KEGG: ttj:TTHA1164 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: C1XQE2 Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
ADH64104.1COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR020625:IPR013785; KEGG: ttj:TTHA0737 putative dihidrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: C1XQ60 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family. (287 aa)
ADH64133.1Putative adenylate/guanylate cyclase; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: ttj:TTHA1259 adenylate cyclase related protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: C1XQ28 Family 3 adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. (703 aa)
dapA2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (313 aa)
ADH64168.14-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR011234:IPR002529:IPR012684; KEGG: dra:DR_A0226 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: C1XPY5 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG2 subunit; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isom [...] (264 aa)
ADH64211.1Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR000634:IPR001926; KEGG: ttj:TTHA0279 putative threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: C1XPU2 L-threonine ammonia-lyase; PFAM: Pyridoxal-phosphate dependent enzyme. (304 aa)
argHCOGs: COG0165 Argininosuccinate lyase; InterProIPR020557:IPR008948:IPR000362:IPR009049:IPR 003031; KEGG: ttj:TTHA0283 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C1XPT6 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (464 aa)
ADH64283.1COGs: COG3629 DNA-binding transcriptional activator of the SARP family; InterPro IPR005158:IPR001867; KEGG: reh:H16_B1607 tow domain-containing protein; PFAM: transcriptional activator domain; transcriptional regulator domain protein; SPTR: C1XPL4 DNA-binding transcriptional activator of the SARP family; PFAM: Bacterial transcriptional activator domain; NACHT domain. (494 aa)
ADH64316.1Fumarate lyase; COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362:IPR008948:IPR020557:IPR003031; KEGG: ddr:Deide_1p00670 putative argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C1XPI0 Argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (480 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
ADH64395.1Protein of unknown function DUF1486; COGs: COG5485 ester cyclase; InterPro IPR009959; KEGG: gvi:glr0227 hypothetical protein; PFAM: protein of unknown function DUF1486; SPTR: C1XP98 Predicted ester cyclase; PFAM: SnoaL-like polyketide cyclase. (139 aa)
ADH64440.1COGs: COG2103 sugar phosphate isomerase; InterPro IPR001347; KEGG: apt:APA01_04290 hypothetical protein; PFAM: sugar isomerase (SIS); SPTR: C1XP50 Predicted sugar phosphate isomerase, COG2103; PFAM: SIS domain; TIGRFAM: N-acetylmuramic acid 6-phosphate etherase. (290 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (219 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisBCOGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR020565:IPR020568:IPR000807; KEGG: tth:TTC0061 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: C1XP22 Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase. (194 aa)
pyrFCOGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterProIPR018089:IPR013785:IPR001754:IPR011995:IPR 011060; KEGG: tth:TTC1381 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: C1XU45 Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. (259 aa)
ADH64596.1dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR016040:IPR005888:IPR001509; KEGG: rca:Rcas_3431 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: C1XU06 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (331 aa)
ADH64658.1Hypothetical protein; KEGG: ter:Tery_2459 clostridial hydrophobic; SPTR: C1XTT8 Putative uncharacterized protein. (210 aa)
mqnDProtein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (280 aa)
deoC-2Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (260 aa)
ADH64823.1Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (234 aa)
ADH64824.1Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: C1XV33 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (348 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (356 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (318 aa)
ADH64909.1KEGG: fps:FP1462 hypothetical protein; SPTR: C1XUU2 Putative uncharacterized protein. (80 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (630 aa)
ADH64980.1O-acetylhomoserineaminocarboxypropyltransferase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR015421:IPR015422:IPR000277:IPR015424; KEGG: tth:TTC0792 QAH/OAS sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: O-acetylhomoserine aminocarboxypropyltransferase; SPTR: C1XYC1 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (418 aa)
ADH65009.1COGs: COG2008 Threonine aldolase; InterPro IPR015424:IPR015422:IPR001597:IPR015421; KEGG: tth:TTC0397 L-allo-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: C1XVC2 L-threonine aldolase; PFAM: Beta-eliminating lyase. (338 aa)
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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