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mfd | Transcription factor CarD; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (988 aa) | ||||
ADH64109.1 | COGs: COG0782 Transcription elongation factor; InterPro IPR018151:IPR001437; KEGG: ttj:TTHA1042 anti-cleavage anti-GreA transcription factor Gfh1; PFAM: transcription elongation factor GreA/GreB domain protein; SPTR: C1XQ55 Transcription elongation factor; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; Belongs to the GreA/GreB family. (158 aa) | ||||
greA | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (159 aa) |