STRINGSTRING
ADH64295.1 ADH64295.1 ADH62039.1 ADH62039.1 ADH63179.1 ADH63179.1 ADH63334.1 ADH63334.1 ADH63433.1 ADH63433.1 ADH63474.1 ADH63474.1 acsA acsA ADH63480.1 ADH63480.1 ADH64181.1 ADH64181.1 ADH64186.1 ADH64186.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADH64295.1AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: tth:TTC0217 putative ABC transporter component; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XPK1 AMP-forming long-chain acyl-CoA synthetase; PFAM: AMP-binding enzyme. (636 aa)
ADH62039.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: rxy:Rxyl_2358 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XRY0 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme. (544 aa)
ADH63179.1AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: ttj:TTHA0511 phenylaceate-CoA ligase/coenzyme F390 synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XXR5 Coenzyme F390 synthetase; PFAM: AMP-binding enzyme. (383 aa)
ADH63334.1COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: tth:TTC0919 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XVW0 Acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. (642 aa)
ADH63433.1AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR000873; KEGG: tth:TTC0079 long-chain-fatty-acid-CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XUM0 AMP-forming long-chain acyl-CoA synthetase; PFAM: AMP-binding enzyme. (651 aa)
ADH63474.1Transcriptional regulator, IclR family; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873:IPR014757:IPR005471; KEGG: tth:TTC0886 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; Transcriptional regulator IclR; regulatory protein IclR; SPTR: C1XUH6 Acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); IclR helix-turn-helix domain; Bacterial transcriptional regulator; AMP-binding enzyme. (835 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
ADH63480.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: ttj:TTHA1463 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XUH0 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme. (559 aa)
ADH64181.1Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (449 aa)
ADH64186.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: tth:TTC0342 acyl-CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XPW7 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme. (496 aa)
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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