STRINGSTRING
eno eno ADH61952.1 ADH61952.1 ADH61964.1 ADH61964.1 dxs dxs ilvE ilvE ADH61998.1 ADH61998.1 ADH62016.1 ADH62016.1 hisG hisG apgM apgM ADH62061.1 ADH62061.1 aroA aroA ndk ndk ADH62113.1 ADH62113.1 pfkA pfkA accD accD accA accA ADH62236.1 ADH62236.1 ADH62240.1 ADH62240.1 ADH62250.1 ADH62250.1 lysA lysA ADH62263.1 ADH62263.1 trpD trpD ADH62282.1 ADH62282.1 trpE trpE lysJ lysJ ADH62294.1 ADH62294.1 ADH62297.1 ADH62297.1 ADH62372.1 ADH62372.1 ADH62373.1 ADH62373.1 lysZ lysZ lysY lysY leuD leuD leuC leuC ADH62385.1 ADH62385.1 ADH62386.1 ADH62386.1 ADH62395.1 ADH62395.1 ispG ispG pgi pgi pckG pckG ctaB ctaB menG menG ADH62579.1 ADH62579.1 ADH62585.1 ADH62585.1 ADH62608.1 ADH62608.1 ADH62612.1 ADH62612.1 ADH62627.1 ADH62627.1 ADH62658.1 ADH62658.1 hisZ hisZ ADH62672.1 ADH62672.1 ADH62677.1 ADH62677.1 ADH62678.1 ADH62678.1 ADH62690.1 ADH62690.1 glgC glgC glgA glgA ADH62748.1 ADH62748.1 ubiX ubiX ispD ispD ispE ispE ADH62831.1 ADH62831.1 thrB thrB glyA glyA ADH62877.1 ADH62877.1 ADH62885.1 ADH62885.1 ADH62891.1 ADH62891.1 ADH62902.1 ADH62902.1 ADH62905.1 ADH62905.1 ADH62907.1 ADH62907.1 ADH62916.1 ADH62916.1 ispH ispH purF purF purL purL purQ purQ purS purS purC purC ADH62963.1 ADH62963.1 surE surE ispF ispF ADH62992.1 ADH62992.1 ADH62998.1 ADH62998.1 ADH63007.1 ADH63007.1 ADH63008.1 ADH63008.1 guaB guaB ADH63034.1 ADH63034.1 ADH63036.1 ADH63036.1 ADH63038.1 ADH63038.1 ADH63039.1 ADH63039.1 ADH63040.1 ADH63040.1 ADH63066.1 ADH63066.1 trpF trpF mqnB mqnB ADH63164.1 ADH63164.1 purK purK purE purE ADH63189.1 ADH63189.1 ADH63196.1 ADH63196.1 ADH63212.1 ADH63212.1 ADH63222.1 ADH63222.1 aroK aroK aroC aroC ADH63230.1 ADH63230.1 ADH63253.1 ADH63253.1 ADH63254.1 ADH63254.1 ADH63306.1 ADH63306.1 ADH63307.1 ADH63307.1 ADH63318.1 ADH63318.1 ADH63320.1 ADH63320.1 ADH63321.1 ADH63321.1 ADH63322.1 ADH63322.1 ADH63326.1 ADH63326.1 ADH63328.1 ADH63328.1 ADH63329.1 ADH63329.1 ADH63330.1 ADH63330.1 ADH63331.1 ADH63331.1 ADH63334.1 ADH63334.1 ADH63360.1 ADH63360.1 ADH63377.1 ADH63377.1 ADH63379.1 ADH63379.1 ADH63380.1 ADH63380.1 ADH63383.1 ADH63383.1 fni fni ADH63394.1 ADH63394.1 gltX gltX mqnA mqnA mqnE mqnE ADH63417.1 ADH63417.1 purN purN purD purD ADH63424.1 ADH63424.1 ADH63474.1 ADH63474.1 acsA acsA ilvD ilvD leuB leuB ADH63489.1 ADH63489.1 leuC-2 leuC-2 ADH63497.1 ADH63497.1 ADH63499.1 ADH63499.1 ADH63500.1 ADH63500.1 ADH63507.1 ADH63507.1 ADH63535.1 ADH63535.1 ADH63567.1 ADH63567.1 ADH63586.1 ADH63586.1 ADH63592.1 ADH63592.1 ADH63594.1 ADH63594.1 mdh mdh ADH63681.1 ADH63681.1 proC proC rpiA rpiA ADH63699.1 ADH63699.1 ADH63702.1 ADH63702.1 ADH63703.1 ADH63703.1 menC menC ADH63709.1 ADH63709.1 trpB trpB trpA trpA ADH63728.1 ADH63728.1 pdhA pdhA ADH63818.1 ADH63818.1 ADH63819.1 ADH63819.1 ADH63820.1 ADH63820.1 ADH63822.1 ADH63822.1 mqnC mqnC dxr dxr ADH63837.1 ADH63837.1 ADH63860.1 ADH63860.1 metXA metXA gcvPB gcvPB gcvPA gcvPA gcvH gcvH gcvT gcvT ADH63886.1 ADH63886.1 ADH63895.1 ADH63895.1 ADH63899.1 ADH63899.1 ADH63900.1 ADH63900.1 tal tal ADH63930.1 ADH63930.1 pgk pgk tpiA tpiA ADH63944.1 ADH63944.1 ADH63947.1 ADH63947.1 ADH63963.1 ADH63963.1 ADH63988.1 ADH63988.1 ADH63998.1 ADH63998.1 ADH64004.1 ADH64004.1 ADH64011.1 ADH64011.1 leuA leuA ilvC ilvC ADH64015.1 ADH64015.1 ADH64016.1 ADH64016.1 fumC fumC ADH64026.1 ADH64026.1 hisF hisF hisI hisI ADH64035.1 ADH64035.1 asd asd sucC sucC sucD sucD ADH64050.1 ADH64050.1 purH purH miaA miaA aroE aroE ADH64100.1 ADH64100.1 ADH64126.1 ADH64126.1 ADH64130.1 ADH64130.1 ADH64154.1 ADH64154.1 dapA dapA ADH64180.1 ADH64180.1 ADH64216.1 ADH64216.1 argH argH argG argG hisD hisD ADH64242.1 ADH64242.1 ADH64244.1 ADH64244.1 ADH64266.1 ADH64266.1 ADH64316.1 ADH64316.1 aroQ aroQ ADH64331.1 ADH64331.1 zwf zwf pgl pgl ADH64340.1 ADH64340.1 ADH64374.1 ADH64374.1 ADH64386.1 ADH64386.1 hisA hisA ADH64407.1 ADH64407.1 ADH64411.1 ADH64411.1 ADH64412.1 ADH64412.1 ADH64413.1 ADH64413.1 acpP acpP ADH64417.1 ADH64417.1 hisH hisH hisB hisB hisC hisC ADH64503.1 ADH64503.1 proB proB proA proA gpsA gpsA ADH64581.1 ADH64581.1 ADH64596.1 ADH64596.1 ADH64597.1 ADH64597.1 ADH64598.1 ADH64598.1 ADH64599.1 ADH64599.1 ADH64600.1 ADH64600.1 purM purM ADH64639.1 ADH64639.1 argJ argJ argC argC ADH64654.1 ADH64654.1 plsY-2 plsY-2 ADH64663.1 ADH64663.1 mqnD mqnD argB argB adk adk ADH64771.1 ADH64771.1 ADH64812.1 ADH64812.1 hemL hemL hemA hemA ADH64822.1 ADH64822.1 ADH64823.1 ADH64823.1 ADH64824.1 ADH64824.1 hemE hemE hemH hemH ADH64830.1 ADH64830.1 ADH64842.1 ADH64842.1 ADH64844.1 ADH64844.1 ADH64856.1 ADH64856.1 plsX plsX ADH64865.1 ADH64865.1 pfkA-2 pfkA-2 ADH64944.1 ADH64944.1 ADH64945.1 ADH64945.1 metK metK ADH64955.1 ADH64955.1 zwf-2 zwf-2 ADH64994.1 ADH64994.1 ADH65009.1 ADH65009.1
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enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
ADH61952.1COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR011037:IPR015793:IPR 015794:IPR001697:IPR018209; KEGG: ttj:TTHA0003 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: C1XVA7 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
ADH61964.1Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR008949:IPR000092; KEGG: ttj:TTHA0013 geranylgeranyl diphosphate synthetase; PFAM: Polyprenyl synthetase; SPTR: C1XS62 Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (332 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (621 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (319 aa)
ADH61998.1InterPro IPR005079; KEGG: chl:Chy400_2318 peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; PFAM: peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; SPTR: C1XS26 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; PFAM: Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase. (354 aa)
ADH62016.1COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR002912:IPR005789; KEGG: cag:Cagg_0043 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: C1XS07 L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. (410 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (206 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (409 aa)
ADH62061.1Zinc-binding alcohol dehydrogenase family protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR016040:IPR011032:IPR013154:IPR014187; KEGG: tro:trd_0582 NAD-dependent alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; SPTR: C1XRV7 Zinc-binding alcohol dehydrogenase family protein; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES-like domain; TIGRFAM: zinc-binding alcohol dehydrogenase family protein. (327 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (425 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa)
ADH62113.1Flavodoxin/nitric oxide synthase; COGs: COG4635 Flavodoxin; InterPro IPR008254; KEGG: mem:Memar_1824 flavodoxin; PFAM: flavodoxin/nitric oxide synthase; SPTR: C1XRQ1 Flavodoxin; PFAM: Flavodoxin. (174 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (293 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa)
ADH62236.1Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR016066:IPR005845:IPR005844:IPR005852:IPR 016055:IPR005846:IPR005843; KEGG: dge:Dgeo_1875 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: C1XRC3 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: [...] (548 aa)
ADH62240.1COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR013786:IPR006091:IPR006089:IPR009100:IPR 006090:IPR013764:IPR006092:IPR009075; KEGG: ttj:TTHA1144 acetyl-coenzyme A dehydrogenase, medium chain; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: C1XRB9 Acyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (381 aa)
ADH62250.1Short-chain dehydrogenase/reductase SDR; COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR016040:IPR002198:IPR002347; KEGG: ttj:TTHA0304 enoyl-[acyl carrier protein] reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XRA7 Enoyl-(Acyl-carrier-protein) reductase (NADH); PFAM: short chain dehydrogenase. (263 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (394 aa)
ADH62263.1COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; InterPro IPR017443:IPR000685; KEGG: rpe:RPE_3678 rubisco-like protein Rlp1; PFAM: ribulose bisphosphate carboxylase large chain; SPTR: C1XR93 Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain. (363 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (346 aa)
ADH62282.1Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR001317:IPR017926:IPR011702:IPR006220:IPR 000991:IPR006221; KEGG: ttj:TTHA1843 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: C1XR74 Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (229 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (469 aa)
lysJAcetylornithine and succinylornithine aminotransferase; Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (395 aa)
ADH62294.1Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (294 aa)
ADH62297.1UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: ttj:TTHA0373 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; PFAM: Carboxylyase-related protein; SPTR: C1XR59 3-octaprenyl-4hydroxybenzoate decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. (606 aa)
ADH62372.1COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123:IPR004552; KEGG: tth:TTC0983 putative acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: C1XQY0 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (212 aa)
ADH62373.1Glycoside hydrolase family 57; COGs: COG1543 conserved hypothetical protein; InterPro IPR011330:IPR015293:IPR004300; KEGG: tth:TTC1540 hypothetical protein; PFAM: glycoside hydrolase family 57; Domain of unknown function DUF1957; SPTR: C1XQX9 Uncharacterized conserved protein; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57. (514 aa)
lysZAcetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily. (269 aa)
lysYN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (344 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (166 aa)
leuC3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (423 aa)
ADH62385.1Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR002034:IPR013785; KEGG: hypothetical protein; PFAM: pyruvate carboxyltransferase; SPTR: C1XQW7 Isopropylmalate/homocitrate/citramalate synthase; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. (413 aa)
ADH62386.1Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (278 aa)
ADH62395.1Glycoside hydrolase family 3 domain protein; InterPro IPR002772:IPR017853; KEGG: mpd:MCP_1311 beta-glucosidase; PFAM: glycoside hydrolase family 3 domain protein; SPTR: C1XY88 Beta-glucosidase-like glycosyl hydrolase; PFAM: Glycosyl hydrolase family 3 C terminal domain. (497 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (407 aa)
pgiPhosphoglucose isomerase (PGI); COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR018189:IPR001672; KEGG: ttj:TTHA0277 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: C1XWJ1 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (445 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (632 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (624 aa)
menGUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (237 aa)
ADH62579.1Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: phe:Phep_2045 aminotransferase class IV; PFAM: aminotransferase class IV; SPTR: C1XWE0 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; PFAM: Aminotransferase class IV. (280 aa)
ADH62585.1Conserved hypothetical protein; COGs: COG3408 Glycogen debranching protein; InterPro IPR008928; KEGG: tth:TTC0614 hypothetical protein; SPTR: C1XWD4 Putative uncharacterized protein; PFAM: Trehalase. (423 aa)
ADH62608.1Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR019800:IPR001764:IPR002772:IPR017853; KEGG: hor:Hore_19810 beta-glucosidase; PFAM: glycoside hydrolase family 3 domain protein; SPTR: C1XWA6 Beta-glucosidase-like glycosyl hydrolase; PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain. (736 aa)
ADH62612.1Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183:IPR011013:IPR014718; KEGG: dge:Dgeo_2023 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: C1XWA2 Galactose mutarotase-like enzyme; PFAM: Aldose 1-epimerase. (306 aa)
ADH62627.1Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839:IPR015421:IPR015424; KEGG: dra:DR_1030 aminotransferase, putative; PFAM: aminotransferase class I and II; SPTR: C1XW84 Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Aminotransferase class I and II. (375 aa)
ADH62658.1Agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR005925:IPR006035:IPR020855; KEGG: aba:Acid345_2118 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: C1XZA9 Agmatinase; TIGRFAM: agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family. (270 aa)
hisZHistidine--tRNA ligase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (386 aa)
ADH62672.1Fructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289:IPR013785; KEGG: ttj:TTHA1773 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: C1XSQ7 Fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. (305 aa)
ADH62677.1Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946:IPR000842; KEGG: ttj:TTHA1549 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: C1XSR2 Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. (361 aa)
ADH62678.1MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (226 aa)
ADH62690.1Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047:IPR013781:IPR017853; KEGG: tth:TTC0107 alpha-glucosidase/glycosyl hydrolase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: C1XSS5 Glycosidase; PFAM: Alpha amylase, catalytic domain. (532 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (413 aa)
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (448 aa)
ADH62748.1Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR013781:IPR006589:IPR017853; KEGG: lbf:LBF_3272 glycosidase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: C1XS91 Glycosidase; PFAM: Alpha amylase, catalytic domain; Domain of unknown function (DUF3459); TIGRFAM: trehalose synthase. (549 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (192 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (209 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (275 aa)
ADH62831.1COGs: COG1482 Phosphomannose isomerase; InterPro IPR011051:IPR014628:IPR001250:IPR014710; KEGG: cag:Cagg_1723 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: C1XSH7 Phosphomannose isomerase; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I. (321 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (290 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (410 aa)
ADH62877.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR016040:IPR002198:IPR002347; KEGG: pfu:PF0149 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XSM6 Putative uncharacterized protein; PFAM: short chain dehydrogenase. (261 aa)
ADH62885.1COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR015421:IPR015424:IPR020578:IPR000192; KEGG: ttj:TTHA0173 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: C1XSN5 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. (379 aa)
ADH62891.1Carbohydrate kinase, thermoresistant glucokinase family; COGs: COG3265 Gluconate kinase; InterPro IPR006001:IPR000623; KEGG: mxa:MXAN_0616 thermosensitive gluconokinase; PFAM: shikimate kinase; SPTR: C1XSP1 Gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family. (165 aa)
ADH62902.1Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR016040:IPR000683:IPR004104; KEGG: kol:Kole_0987 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: C1XZA4 Predicted dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (326 aa)
ADH62905.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (787 aa)
ADH62907.1COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR002937:IPR014105; KEGG: rca:Rcas_3488 zeta-phytoene desaturase; PFAM: amine oxidase; SPTR: C1XZ99 Phytoene desaturase; TIGRFAM: phytoene desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase. (549 aa)
ADH62916.1COGs: COG2224 Isocitrate lyase; InterPro IPR006254:IPR018523:IPR000918:IPR015813; KEGG: ttj:TTHA1836 isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; SPTR: C1XZ89 Isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase. (429 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (343 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (491 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (743 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (228 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (86 aa)
purCCOGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR013816:IPR001636:IPR018236; KEGG: tth:TTC1151 phosphoribosylamidoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: C1XXF3 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (235 aa)
ADH62963.1COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR003031:IPR008948:IPR020557:IPR 019468:IPR004769; KEGG: tth:TTC1149 putative adenylosuccinate lyase protein; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: C1XXF2 Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (436 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (265 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (167 aa)
ADH62992.1COGs: COG0031 Cysteine synthase; InterProIPR005856:IPR001926:IPR000634:IPR001216:IPR 005859; KEGG: tth:TTC1636 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: C1XXC3 Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa)
ADH62998.1COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: ttj:TTHA0634 magnesium chelatase related protein; SPTR: C1XXB7 Mg-chelatase subunit ChlI. (473 aa)
ADH63007.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: dth:DICTH_0637 ribokinase:carbohydrate kinase, PfkB; PFAM: PfkB domain protein; SPTR: C1XXA7 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (306 aa)
ADH63008.1Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR018225:IPR013785; KEGG: amr:AM1_1655 transaldolase, putative; PFAM: Transaldolase; SPTR: C1XXA6 Transaldolase; PFAM: Transaldolase; TIGRFAM: transaldolase, putative, TalC family. (217 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (503 aa)
ADH63034.1COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140:IPR016195:IPR004013; KEGG: tth:TTC1652 histidinol-phosphatase; PFAM: PHP domain protein; SPTR: C1XX78 Histidinol-phosphate phosphatase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; Belongs to the PHP hydrolase family. HisK subfamily. (262 aa)
ADH63036.1COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR012999:IPR013027:IPR006258:IPR004099:IPR 000815:IPR001327:IPR016156; KEGG: ttj:TTHA0233 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1XX76 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, di [...] (464 aa)
ADH63038.1Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR004167:IPR001078:IPR000089:IPR003016:IPR 011053; KEGG: ttj:TTHA0232 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1XX74 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogen [...] (476 aa)
ADH63039.1Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR015941:IPR009014:IPR005475:IPR005476; KEGG: ttj:TTHA0230 2-oxoisovalerate dehydrogenase, E1 component beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SPTR: C1XX73 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (324 aa)
ADH63040.13-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: tth:TTC1757 2-oxoisovalerate dehydrogenase alpha subunit; PFAM: dehydrogenase E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: C1XX72 Branched-chain alpha-keto acid dehydrogenase E1 component; PFAM: Dehydrogenase E1 component. (368 aa)
ADH63066.1Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR013781:IPR017853:IPR006047:IPR006589; KEGG: tth:TTC1283 maltodextrin glucosidase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: C1XYP4 Glycosidase; PFAM: Alpha amylase, catalytic domain. (576 aa)
trpFCOGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR013785:IPR011060:IPR001240; KEGG: tth:TTC1929 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: C1XXV7 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (206 aa)
mqnBFutalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (223 aa)
ADH63164.1Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterProIPR010954:IPR020822:IPR006268:IPR006218:IPR 013785:IPR002701; KEGG: ttj:TTHA0388 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SMART: Chorismate mutase; SPTR: C1XXT0 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; chorismate mutase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; chorismate mutase; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: cho [...] (358 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (171 aa)
ADH63189.1COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR014273:IPR019818:IPR001804; KEGG: gwc:GWCH70_0444 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: C1XXQ4 Isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (480 aa)
ADH63196.1Alpha amylase catalytic region; COGs: COG0296 1 4-alpha-glucan branching enzyme; InterProIPR017853:IPR006047:IPR006048:IPR006589:IPR 013781; KEGG: gvi:gll1431 alpha-glucanotransferase; PFAM: alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; SPTR: C1XXP6 1,4-alpha-glucan branching enzyme; PFAM: Alpha amylase, C-terminal all-beta domain; Alpha amylase, catalytic domain. (541 aa)
ADH63212.1Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047:IPR013781:IPR017853; KEGG: ttj:TTHA1563 (neo)pullulanase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: C1XXM9 Glycosidase; PFAM: Alpha amylase, catalytic domain. (486 aa)
ADH63222.1COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658:IPR016303; KEGG: tth:TTC1020 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: C1XXL8 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase. (351 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (219 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (383 aa)
ADH63230.1COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR019818:IPR001804; KEGG: ttj:TTHA1378 homoisocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: C1XXL0 Homoisocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; isopropylmalate/isohomocitrate dehydrogenases. (334 aa)
ADH63253.1COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: rmr:Rmar_1263 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: C1XW42 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (428 aa)
ADH63254.1COGs: COG0460 Homoserine dehydrogenase; InterProIPR018488:IPR019811:IPR016040:IPR005106:IPR 001342; KEGG: ttj:TTHA0489 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: C1XW41 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain. (339 aa)
ADH63306.1Alpha-1,6-glucosidase, pullulanase-type; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterProIPR005323:IPR014756:IPR011839:IPR004193:IPR 006047:IPR013781:IPR017853; KEGG: ddr:Deide_15110 putative pullulanase precursor (alpha-dextrin endo-1,6-alpha-glucosidase)(pullulan 6-glucanohydrolase); PFAM: pullanase-associated protein; glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SPTR: C1XVY8 Alpha-1,6-glucosidase, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: Domain of unknown function (DUF3372); A [...] (1117 aa)
ADH63307.1Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterProIPR006589:IPR006048:IPR006047:IPR013781:IPR 017853; KEGG: tga:TGAM_1752 pullulan hydrolase type III (pulhA); PFAM: alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; SPTR: C1XVY7 Glycosidase; PFAM: Alpha amylase, C-terminal all-beta domain; Alpha amylase, catalytic domain. (703 aa)
ADH63318.1Hydroxypyruvate reductase; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: dge:Dgeo_2615 hydroxypyruvate reductase; PFAM: MOFRL domain protein; PRIAM: Hydroxypyruvate reductase; SPTR: C1XVX6 Glycerate 2-kinase; PFAM: MOFRL family. (424 aa)
ADH63320.1Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR017896:IPR001450:IPR012285:IPR017900:IPR 004017:IPR012257:IPR009051; KEGG: dra:DR_1730 glycolate oxidase, iron-sulfur subunit; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C1XVX4 Fe-S oxidoreductase; PFAM: Cysteine-rich domain. (420 aa)
ADH63321.1FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166:IPR006094:IPR016168; KEGG: tth:TTC0128 (S)-2-hydroxy-acid oxidase subunit GlcE; PFAM: FAD linked oxidase domain protein; SPTR: C1XVX3 FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain. (362 aa)
ADH63322.1FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166:IPR016164:IPR016167:IPR006094:IPR 004113; KEGG: ttj:TTHA0505 glycolate oxidase subunit; PFAM: FAD linked oxidase domain protein; SPTR: C1XVX2 FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (487 aa)
ADH63326.1COGs: COG2225 Malate synthase; InterPro IPR019830:IPR011076:IPR006252; KEGG: rmr:Rmar_2163 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: C1XVW8 Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (521 aa)
ADH63328.1InterPro IPR014314:IPR000701; KEGG: ttj:TTHA1456 succinate dehydrogenase, cytochrome subunit; PFAM: succinate dehydrogenase cytochrome b subunit; SPTR: C1XVW6 Succinate dehydrogenase subunit C; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit. (123 aa)
ADH63329.1KEGG: ttj:TTHA1455 succinate dehydrogenase, membrane subunit (SdhD); SPTR: C1XVW5 Succinate dehydrogenase subunit D; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit. (130 aa)
ADH63330.1COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterProIPR003952:IPR004112:IPR013027:IPR003953:IPR 014006:IPR015939:IPR011281; KEGG: ttj:TTHA1454 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: C1XVW4 Succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgr [...] (577 aa)
ADH63331.1COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041:IPR017896:IPR012675:IPR012285:IPR 009051:IPR017900:IPR004489; KEGG: tth:TTC1089 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: C1XVW3 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (232 aa)
ADH63334.1COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: tth:TTC0919 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1XVW0 Acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. (642 aa)
ADH63360.1COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385:IPR013781:IPR017853; KEGG: ttj:TTHA1261 4-alpha-glucanotransferase (amylomaltase) (disproportionating enzyme) (D-enzyme); PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: C1XVT1 Amylomaltase or 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase. (500 aa)
ADH63377.1COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR008949:IPR002060; KEGG: ttj:TTHB101 phytoene synthase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: C1XVR2 Phytoene synthase; PFAM: Squalene/phytoene synthase. (280 aa)
ADH63379.1InterPro IPR008671; KEGG: chl:Chy400_1967 lycopene beta and epsilon cyclase; PFAM: Lycopene beta and epsilon cyclase; SPTR: C1XVR0 FAD dependent oxidoreductase; PFAM: Lycopene cyclase protein; TIGRFAM: lycopene cyclase family protein. (388 aa)
ADH63380.1Protein of unknown function DUF422; COGs: COG2324 membrane protein; InterPro IPR007354; KEGG: ddr:Deide_2p01210 hypothetical protein; putative membrane protein; PFAM: protein of unknown function DUF422; SPTR: C1XVQ9 Predicted membrane protein, COG2324; PFAM: Protein of unknown function (DUF422). (397 aa)
ADH63383.1FAD dependent oxidoreductase; COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR006076; KEGG: dra:DR_2250 methoxyneurosporene dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: C1XVQ6 Phytoene dehydrogenase-like oxidoreductase; PFAM: FAD dependent oxidoreductase; TIGRFAM: phytoene desaturase. (447 aa)
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (338 aa)
ADH63394.1Dimethylallyltranstransferase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092:IPR008949; KEGG: tth:TTC1291 octaprenyl-diphosphate synthase; PFAM: Polyprenyl synthetase; PRIAM: Dimethylallyltranstransferase; SPTR: C1XUR7 Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (319 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (476 aa)
mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (271 aa)
mqnERadical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (396 aa)
ADH63417.1Protein of unknown function DUF205; COGs: COG0344 membrane protein; InterPro IPR003811; KEGG: ttj:TTHA0808 hypothetical protein; PFAM: protein of unknown function DUF205; SPTR: C1XUN9 Predicted membrane protein, COG0344; PFAM: Domain of unknown function (DUF205); TIGRFAM: conserved hypothetical integral membrane protein TIGR00023; Belongs to the PlsY family. (182 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (197 aa)
purDCOGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR020559:IPR000115:IPR016185:IPR011054:IPR 020562:IPR020561:IPR020560:IPR013817:IPR013815:IPR013816:I PR011761; KEGG: tth:TTC0460 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: C1XUN4 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribo [...] (423 aa)
ADH63424.1Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR020550:IPR020583:IPR000760; KEGG: tth:TTC1928 myo-inositol-1(or 4)-monophosphatase; PFAM: inositol monophosphatase; SPTR: C1XUN2 Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; PFAM: Inositol monophosphatase family. (258 aa)
ADH63474.1Transcriptional regulator, IclR family; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873:IPR014757:IPR005471; KEGG: tth:TTC0886 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; Transcriptional regulator IclR; regulatory protein IclR; SPTR: C1XUH6 Acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); IclR helix-turn-helix domain; Bacterial transcriptional regulator; AMP-binding enzyme. (835 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
ilvDCOGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR020558:IPR004404; KEGG: ttj:TTHA1234 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C1XUG4 Dihydroxyacid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (554 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa)
ADH63489.13-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuC-23-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
ADH63497.1COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: tth:TTC0191 acetyl-CoA acetyltransferase; SPTR: C1XUF1 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ADH63499.1COGs: COG0287 Prephenate dehydrogenase; InterPro IPR016040:IPR003099:IPR002912; KEGG: ttj:TTHA0799 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydrogenase; SPTR: C1XUE9 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; ACT domain. (360 aa)
ADH63500.1Thioesterase superfamily protein; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR003736:IPR006683; KEGG: ttj:TTHA1546 thioesterase family protein; PFAM: thioesterase superfamily protein; SPTR: C1XUE8 Uncharacterized conserved protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1. (136 aa)
ADH63507.12-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterPro IPR002020:IPR016141:IPR011278:IPR016142; KEGG: tth:TTC0978 citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: C1XUE1 Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. (379 aa)
ADH63535.1Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR004821:IPR015864:IPR002606; KEGG: ttj:TTHA0527 riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; SMART: Riboflavin kinase; SPTR: C1XUB0 FMN adenylyltransferase; riboflavin kinase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. (296 aa)
ADH63567.1Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR004439:IPR019818; KEGG: rmr:Rmar_1401 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; SPTR: C1XU73 Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (425 aa)
ADH63586.1COGs: COG0069 Glutamate synthase domain 2; InterProIPR006982:IPR002489:IPR002932:IPR017932:IPR 000583; KEGG: ttj:TTHA1468 glutamate synthase, large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: C1XYW8 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1518 aa)
ADH63592.1COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376:IPR001753; KEGG: ara:Arad_0598 enoyl-CoA hydratase protein; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C1XYW2 Short chain enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
ADH63594.1COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR018042:IPR002912:IPR 005260; KEGG: ttj:TTHA0534 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; PRIAM: Aspartate kinase; SPTR: C1XYW0 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (406 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
ADH63681.1COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038:IPR002155; KEGG: ttj:TTHA0891 acetyl-CoA acetyltransferase; SPTR: C1XT95 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (260 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa)
ADH63699.1COGs: COG4401 Chorismate mutase; InterPro IPR008243:IPR013813; KEGG: ttj:TTHA0868 chorismate mutase; PFAM: Chorismate mutase of the AroH class; SPTR: C1XT74 Chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1. (122 aa)
ADH63702.1Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: tth:TTC0517 chlorohydrolase; PFAM: amidohydrolase; SPTR: C1XT71 Cytosine deaminase-like metal-dependent hydrolase; PFAM: Amidohydrolase family. (368 aa)
ADH63703.1COGs: COG3375 conserved hypothetical protein; InterPro IPR000182:IPR016181; KEGG: ttj:TTHA0873 hypothetical protein; SPTR: C1XT70 Uncharacterized conserved protein. (262 aa)
menCO-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (372 aa)
ADH63709.1COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (475 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (417 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)
ADH63728.1Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: ttj:TTHA0938 pyruvate dehydrogenase E1 component, beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1XT03 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (335 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (346 aa)
ADH63818.1COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603:IPR005475:IPR001017; KEGG: ttj:TTHA0289 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component; PRIAM: Oxoglutarate dehydrogenase (succinyl-transferring); SMART: Transketolase central region; SPTR: C1XT57 2-oxoglutarate dehydrogenase E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. (919 aa)
ADH63819.12-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (422 aa)
ADH63820.1COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR012999:IPR013027:IPR006258:IPR004099:IPR 000815:IPR001327:IPR016156; KEGG: tth:TTC1700 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1XT55 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide d [...] (459 aa)
ADH63822.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1223 aa)
mqnCRadical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (379 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (374 aa)
ADH63837.1Phosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: ttj:TTHA0857 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: C1XT37 Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. (275 aa)
ADH63860.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (463 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (388 aa)
gcvPBGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (484 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (433 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (350 aa)
ADH63886.1Trehalose synthase; COGs: COG0366 Glycosidase; InterProIPR006589:IPR012810:IPR006047:IPR013781:IPR 017853; KEGG: mxa:MXAN_3684 trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: C1XQT7 Trehalose synthase; TIGRFAM: trehalose synthase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase. (551 aa)
ADH63895.1Transketolase; COGs: COG0021 Transketolase; InterProIPR005478:IPR009014:IPR005474:IPR005475:IPR 005476:IPR015941; KEGG: ttj:TTHA0108 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: C1XQS8 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family. (655 aa)
ADH63899.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (173 aa)
ADH63900.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (219 aa)
ADH63930.1COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020830:IPR016040:IPR020828:IPR006424:IPR 020831:IPR020832:IPR020829; KEGG: tth:TTC0549 glyceraldehyde 3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: C1XQP3 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate [...] (330 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015901:IPR015911:IPR015824; KEGG: pzu:PHZ_p0042 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: C1XQP2 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
ADH63944.1COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845:IPR018016; KEGG: ttj:TTHA1435 purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: C1XQN0 Purine-nucleoside phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD). (240 aa)
ADH63947.1COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056:IPR011060:IPR013785; KEGG: ttj:TTHA0106 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: C1XQM7 Ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. (224 aa)
ADH63963.1Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. (280 aa)
ADH63988.1COGs: COG0058 Glucan phosphorylase; InterPro IPR000811:IPR011834; KEGG: tth:TTC0808 glycogen phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: C1XQI3 Phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases. (832 aa)
ADH63998.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa)
ADH64004.1FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166:IPR016164:IPR006094:IPR004113:IPR 016167; KEGG: dge:Dgeo_0624 FAD linked oxidase-like protein; PFAM: FAD linked oxidase domain protein; SPTR: C1XQG6 FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (457 aa)
ADH64011.12-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterProIPR005675:IPR013709:IPR000891:IPR013785:IPR 002034; KEGG: tth:TTC0847 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; SPTR: C1XQF9 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family prote [...] (528 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (519 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
ADH64015.1COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR004789:IPR019455; KEGG: ttj:TTHA1212 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: C1XQF5 Acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (170 aa)
ADH64016.1Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012846:IPR012001:IPR012000:IPR011766:IPR 000399; KEGG: tth:TTC0852 acetolactate synthase large subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C1XJ74 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-termi [...] (562 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
ADH64026.1COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR013785:IPR011060:IPR001468; KEGG: ttj:TTHA1164 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: C1XQE2 Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
hisIphosphoribosyl-ATP diphosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179:IPR002496; KEGG: ttj:TTHA1445 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; SPTR: C1XQD4 Phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; b [...] (215 aa)
ADH64035.1Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: ttj:TTHA1446 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: C1XQD3 Fructose-1,6-bisphosphatase, class II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II. (322 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
ADH64050.1Hydroxymethylglutaryl-CoA lyase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013785; KEGG: ttj:TTHA1526 hydroxymethylglutaryl-CoA lyase like protein; PFAM: pyruvate carboxyltransferase; PRIAM: Hydroxymethylglutaryl-CoA lyase; SPTR: C1XQB7 Hydroxymethylglutaryl-CoA lyase; PFAM: HMGL-like. (282 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982:IPR002695; KEGG: dge:Dgeo_0513 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SPTR: C1XQA7 IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase [...] (502 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa)
ADH64100.1COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: ttj:TTHA1044 diacylglycerol kinase; PFAM: diacylglycerol kinase; SPTR: C1XJH3 Diacylglycerol kinase; PFAM: Prokaryotic diacylglycerol kinase. (131 aa)
ADH64126.1HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR006402:IPR006439; KEGG: saz:Sama_0499 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C1XQ37 Haloacid dehalogenase superfamily enzyme, subfamily IA; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase supe [...] (191 aa)
ADH64130.1Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (275 aa)
ADH64154.1COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR013786:IPR006091:IPR006090:IPR009100:IPR 013764:IPR006092:IPR009075; KEGG: rmr:Rmar_2207 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain protein; PRIAM: Butyryl-CoA dehydrogenase; SPTR: C1XQ04 Acyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (398 aa)
dapA2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (313 aa)
ADH64180.1COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038:IPR002155; KEGG: tth:TTC0623 beta-ketoadipyl CoA thiolase; SPTR: C1XPX3 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ADH64216.1GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182:IPR016181; KEGG: ttj:TTHA0282 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: C1XPT7 N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family; Belongs to the acetyltransferase family. (180 aa)
argHCOGs: COG0165 Argininosuccinate lyase; InterProIPR020557:IPR008948:IPR000362:IPR009049:IPR 003031; KEGG: ttj:TTHA0283 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C1XPT6 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (464 aa)
argGCOGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518:IPR014729; KEGG: ttj:TTHA0284 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: C1XPT4 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (397 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (422 aa)
ADH64242.1COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterProIPR016040:IPR006140:IPR002912:IPR006236:IPR 006139; KEGG: tth:TTC0586 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: C1XPQ7 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic do [...] (521 aa)
ADH64244.1COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: tth:TTC0240 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XPQ5 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. (283 aa)
ADH64266.1Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: nca:Noca_3921 aminotransferase; PFAM: aminotransferase class-III; SPTR: C1XPN3 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
ADH64316.1Fumarate lyase; COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362:IPR008948:IPR020557:IPR003031; KEGG: ddr:Deide_1p00670 putative argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C1XPI0 Argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (480 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
ADH64331.16-phosphogluconate dehydrogenase, decarboxylating; COGs: COG1023 6-phosphogluconate dehydrogenase; InterProIPR004849:IPR016040:IPR002204:IPR006115:IPR 013328:IPR008927:IPR006114:IPR006183; KEGG: mei:Msip34_1094 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: C1XPG5 6-phosphogluconate dehydrogenase (Decarboxylating); TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-termin [...] (303 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (457 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (218 aa)
ADH64340.15'-Nucleotidase domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006146:IPR004843:IPR008334:IPR006179; KEGG: tth:TTC0964 5'-nucleotidase; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; SPTR: C1XPF6 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; TIGRFAM: NAD pyrophosphatase/5'-nucleotidase NadN; Belongs to the 5'-nucleotidase family. (558 aa)
ADH64374.1COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR013786:IPR006091:IPR006089:IPR009100:IPR 006090:IPR013764:IPR009075:IPR006092; KEGG: ttj:TTHA0789 putative glutaryl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: C1XPC2 Acyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (386 aa)
ADH64386.1Glyoxylate reductase; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR016040:IPR006140:IPR006139; KEGG: tth:TTC0431 glycerate dehydrogenase/glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; PRIAM: Glyoxylate reductase; SPTR: C1XPA7 Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (318 aa)
hisACOGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR013785:IPR011060:IPR006063:IPR006062; KEGG: ttj:TTHA1165 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: C1XP87 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: His [...] (233 aa)
ADH64407.1Arginase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005924:IPR014033; KEGG: ttj:TTHA1496 arginase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: C1XP86 Arginase; TIGRFAM: arginase; PFAM: Arginase family; TIGRFAM: arginase; Belongs to the arginase family. (298 aa)
ADH64411.1COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterProIPR016035:IPR014043:IPR004410:IPR016036:IPR 001227; KEGG: ttj:TTHA0416 malonyl CoA-[acyl carrier protein] transacylase; PFAM: Acyl transferase; SPTR: C1XP82 (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (304 aa)
ADH64412.13-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
ADH64413.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR016040:IPR002347; KEGG: ter:Tery_4543 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XP79 Putative uncharacterized protein; PFAM: short chain dehydrogenase. (249 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
ADH64417.1Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR015424:IPR004839:IPR015422:IPR015421; KEGG: dge:Dgeo_2084 aminotransferase, class I and II; PFAM: aminotransferase class I and II; SPTR: C1XP75 Valine-pyruvate aminotransferase; PFAM: Aminotransferase class I and II. (397 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisBCOGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR020565:IPR020568:IPR000807; KEGG: tth:TTC0061 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: C1XP22 Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase. (194 aa)
hisCCOGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR015421:IPR001917:IPR015424:IPR005861:IPR 004839; KEGG: ttj:TTHA0428 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XP21 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (352 aa)
ADH64503.1Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR016040:IPR000683:IPR004104; KEGG: ddr:Deide_3p01930 putative NADH-dependent dyhydrogenase, putative inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: C1XNY5 Predicted dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (325 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (383 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa)
gpsACOGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterProIPR016040:IPR006168:IPR011128:IPR013328:IPR 008927:IPR006109; KEGG: ttj:TTHA1740 glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); SPTR: C1XU48 Glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (316 aa)
ADH64581.1Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: ttj:TTHA1637 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: C1XU23 Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. (308 aa)
ADH64596.1dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR016040:IPR005888:IPR001509; KEGG: rca:Rcas_3431 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: C1XU06 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (331 aa)
ADH64597.1dTDP-4-dehydrorhamnose 35-epimerase related protein; COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR011051:IPR000888:IPR014710; KEGG: ddr:Deide_20315 putative dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; SPTR: C1XU05 dTDP-4-dehydrorhamnose 3,5-epimerase-like enzyme; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase. (176 aa)
ADH64598.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (240 aa)
ADH64599.1Glucose-1-phosphate thymidyltransferase; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR011004:IPR005908:IPR005835; KEGG: tth:TTC1762 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; SPTR: C1XU03 Glucose-1-phosphate thymidylylransferase, long form; TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form. (355 aa)
ADH64600.1Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterProIPR011051:IPR001538:IPR005835:IPR006375:IPR 014710; KEGG: afr:AFE_3293 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; SPTR: C1XU02 Mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransfe [...] (476 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918:IPR016188:IPR004733:IPR000728; KEGG: tth:TTC1619 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: C1XTX0 Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phospho [...] (335 aa)
ADH64639.1Glucose-1-phosphate thymidyltransferase; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR011004:IPR005908:IPR005835:IPR001451; KEGG: tth:TTC1762 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: C1XTW2 Glucose-1-phosphate thymidylylransferase, long form; TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form. (354 aa)
argJArginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (380 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (323 aa)
ADH64654.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (313 aa)
plsY-2Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (205 aa)
ADH64663.1FAD dependent oxidoreductase; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR000447:IPR006076; KEGG: gbm:Gbem_3375 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: C1XTT3 Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (531 aa)
mqnDProtein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (280 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (276 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (183 aa)
ADH64771.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR016040:IPR002347; KEGG: ttj:TTHA0461 dihydropteridine/dihydrofolate reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XV89 Dihydropteridine reductase; PFAM: short chain dehydrogenase. (235 aa)
ADH64812.1ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ttj:TTHA0299 glucokinase; PFAM: ROK family protein; SPTR: C1XV45 Glucokinase; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (300 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015424:IPR005814:IPR004639:IPR015421; KEGG: dra:DR_0555 glutamate-1-semialdehyde aminotransferase; PFAM: aminotransferase class-III; SPTR: C1XV37 Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (434 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (392 aa)
ADH64822.1Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (304 aa)
ADH64823.1Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (234 aa)
ADH64824.1Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: C1XV33 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (348 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (356 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (318 aa)
ADH64830.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (460 aa)
ADH64842.1COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: ttj:TTHA0220 hypoxanthine-guanine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: C1XV15 Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
ADH64844.1COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376:IPR001753; KEGG: sro:Sros_3993 enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C1XV13 Enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa)
ADH64856.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II. (383 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (330 aa)
ADH64865.1Putative glycolate oxidase subunit GlcE; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166; KEGG: ddr:Deide_14041 putative glycolate oxidase subunit GlcE; SPTR: C1XUZ1 Putative uncharacterized protein. (234 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (322 aa)
ADH64944.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa)
ADH64945.1Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR004167:IPR001078:IPR000089:IPR003016:IPR 011053; KEGG: ttj:TTHA0184 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1XYG5 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogen [...] (428 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (391 aa)
ADH64955.1COGs: COG0506 Proline dehydrogenase; InterPro IPR008219:IPR002872; KEGG: tth:TTC1214 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Proline dehydrogenase; SPTR: C1XYF5 L-proline dehydrogenase; PFAM: Proline dehydrogenase. (307 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (480 aa)
ADH64994.1Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR015424:IPR004839:IPR015421; KEGG: dra:DR_1452 aminotransferase, class I; PFAM: aminotransferase class I and II; SPTR: C1XVE0 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II. (390 aa)
ADH65009.1COGs: COG2008 Threonine aldolase; InterPro IPR015424:IPR015422:IPR001597:IPR015421; KEGG: tth:TTC0397 L-allo-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: C1XVC2 L-threonine aldolase; PFAM: Beta-eliminating lyase. (338 aa)
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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