(40 nodes) Formation of the Early Elongation Complex, and Transcription factor TFIIA complex network (Austrofundulus limnaeus)

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Your Input:
	gtf2h5	General transcription factor IIH subunit 5. (71 aa)
	LOC106512772	DNA-directed RNA polymerase II subunit RPB4-like. (139 aa)
	ercc3	TFIIH basal transcription factor complex helicase XPB subunit. (783 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
	polr2g	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	polr2k	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
	LOC106519707	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (253 aa)
	polr2f	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
	gtf2h1	General transcription factor IIH subunit 1. (550 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	ercc2	TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (782 aa)
	gtf2e1	General transcription factor IIE subunit 1. (445 aa)
	gtf2h3	General transcription factor IIH subunit 3 isoform X1. (300 aa)
	LOC106523888	Flocculation protein FLO11-like. (327 aa)
	ercc6	DNA excision repair protein ERCC-6. (1438 aa)
	tcea1	Transcription elongation factor A protein 1 isoform X1. (311 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1910 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (530 aa)
	gtf2a1	Transcription initiation factor IIA subunit 1. (389 aa)
	supt4h1	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
	LOC106528505	Transcription elongation factor A protein 2-like. (305 aa)
	LOC106530021	Uncharacterized protein LOC106530021. (259 aa)
	gtf2b	Transcription initiation factor IIB. (318 aa)
	polr2l	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)
	ctdp1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (977 aa)
	polr2j	DNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
	LOC106531760	General transcription factor IIH subunit. (392 aa)
	LOC106532059	DNA-directed RNA polymerase II subunit RPB2-like. (367 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	polr2e	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
	LOC106532634	DNA-directed RNA polymerase II subunit RPB4. (143 aa)
	LOC106533313	DNA-directed RNA polymerase II subunit RPB1-like. (290 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	supt5h	Transcription elongation factor SPT5. (1080 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	polr2c	DNA-directed RNA polymerase II subunit RPB3. (275 aa)
	LOC106536878	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	ccnh	cyclin-H; Belongs to the cyclin family. (319 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106512772	LOC106519707	A0A2I4AMM8	A0A2I4BGQ9	DNA-directed RNA polymerase II subunit RPB4-like.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.897
LOC106512772	LOC106523888	A0A2I4AMM8	A0A2I4BYU4	DNA-directed RNA polymerase II subunit RPB4-like.	Flocculation protein FLO11-like.	0.862
LOC106512772	LOC106528505	A0A2I4AMM8	A0A2I4CGM5	DNA-directed RNA polymerase II subunit RPB4-like.	Transcription elongation factor A protein 2-like.	0.831
LOC106512772	LOC106530021	A0A2I4AMM8	A0A2I4CM08	DNA-directed RNA polymerase II subunit RPB4-like.	Uncharacterized protein LOC106530021.	0.812
LOC106512772	LOC106531760	A0A2I4AMM8	A0A2I4CT17	DNA-directed RNA polymerase II subunit RPB4-like.	General transcription factor IIH subunit.	0.942
LOC106512772	LOC106532059	A0A2I4AMM8	A0A2I4CU40	DNA-directed RNA polymerase II subunit RPB4-like.	DNA-directed RNA polymerase II subunit RPB2-like.	0.917
LOC106512772	LOC106532634	A0A2I4AMM8	A0A2I4CW42	DNA-directed RNA polymerase II subunit RPB4-like.	DNA-directed RNA polymerase II subunit RPB4.	0.900
LOC106512772	LOC106533313	A0A2I4AMM8	A0A2I4CYI1	DNA-directed RNA polymerase II subunit RPB4-like.	DNA-directed RNA polymerase II subunit RPB1-like.	0.862
LOC106512772	LOC106536878	A0A2I4AMM8	A0A2I4DBR0	DNA-directed RNA polymerase II subunit RPB4-like.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.928
LOC106512772	ccnh	A0A2I4AMM8	A0A2I4DC97	DNA-directed RNA polymerase II subunit RPB4-like.	cyclin-H; Belongs to the cyclin family.	0.875
LOC106512772	cdk7	A0A2I4AMM8	A0A2I4D2I3	DNA-directed RNA polymerase II subunit RPB4-like.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.765
LOC106512772	ctdp1	A0A2I4AMM8	A0A2I4CR83	DNA-directed RNA polymerase II subunit RPB4-like.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.903
LOC106512772	ercc2	A0A2I4AMM8	A0A2I4BUF5	DNA-directed RNA polymerase II subunit RPB4-like.	TFIIH basal transcription factor complex helicase XPD subunit isoform X1.	0.944
LOC106512772	ercc3	A0A2I4AMM8	A0A2I4ASK7	DNA-directed RNA polymerase II subunit RPB4-like.	TFIIH basal transcription factor complex helicase XPB subunit.	0.944
LOC106512772	ercc6	A0A2I4AMM8	A0A2I4C065	DNA-directed RNA polymerase II subunit RPB4-like.	DNA excision repair protein ERCC-6.	0.950
LOC106512772	gtf2a1	A0A2I4AMM8	A0A2I4C8Q1	DNA-directed RNA polymerase II subunit RPB4-like.	Transcription initiation factor IIA subunit 1.	0.812
LOC106512772	gtf2b	A0A2I4AMM8	A0A2I4CN27	DNA-directed RNA polymerase II subunit RPB4-like.	Transcription initiation factor IIB.	0.970
LOC106512772	gtf2e1	A0A2I4AMM8	A0A2I4BW06	DNA-directed RNA polymerase II subunit RPB4-like.	General transcription factor IIE subunit 1.	0.949
LOC106512772	gtf2e2	A0A2I4AMM8	A0A2I4AXW2	DNA-directed RNA polymerase II subunit RPB4-like.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.940
LOC106512772	gtf2f1	A0A2I4AMM8	A0A2I4C8M4	DNA-directed RNA polymerase II subunit RPB4-like.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.963