(35 nodes) Mixed, incl. L27 domain, and TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106511184	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family. (592 aa)
	LOC106511261	Uncharacterized protein LOC106511261. (554 aa)
	arhgef18	Rho guanine nucleotide exchange factor 18 isoform X1. (1628 aa)
	mpp4	MAGUK p55 subfamily member 4 isoform X1; Belongs to the MAGUK family. (642 aa)
	mpdz	Multiple PDZ domain protein. (2090 aa)
	LOC106515202	Multiple PDZ domain protein-like. (1883 aa)
	LOC106515848	Partitioning defective 6 homolog gamma-like. (461 aa)
	prkci	Protein kinase C iota type; Belongs to the protein kinase superfamily. (402 aa)
	LOC106516857	Rho guanine nucleotide exchange factor 18-like. (960 aa)
	LOC106517273	MAGUK p55 subfamily member 4-like; Belongs to the MAGUK family. (609 aa)
	LOC106521070	MAGUK p55 subfamily member 7-like. (311 aa)
	LOC106521063	Partitioning defective 3 homolog. (504 aa)
	LOC106521234	MAGUK p55 subfamily member 5-A-like; Belongs to the MAGUK family. (670 aa)
	LOC106522197	Protein crumbs homolog 1-like. (1025 aa)
	mpp5	MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (647 aa)
	epb41l4b	Band 4.1-like protein 4B isoform X1. (790 aa)
	LOC106523998	Partitioning defective 6 homolog alpha-like isoform X1. (425 aa)
	lnx1	E3 ubiquitin-protein ligase LNX isoform X1. (765 aa)
	LOC106524667	Partitioning defective 3 homolog B-like isoform X1. (1281 aa)
	LOC106524841	MAGUK p55 subfamily member 7-like; Belongs to the MAGUK family. (457 aa)
	LOC106525923	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (608 aa)
	LOC106526992	Partitioning defective 3 homolog B-like. (727 aa)
	LOC106526993	Partitioning defective 3 homolog B-like isoform X1. (444 aa)
	LOC106527433	MAGUK p55 subfamily member 3-like. (424 aa)
	LOC106528062	inaD-like protein. (307 aa)
	LOC106529583	Protein crumbs homolog 1-like isoform X1. (1462 aa)
	LOC106532169	inaD-like protein. (1128 aa)
	LOC106532170	inaD-like protein. (704 aa)
	pard6b	Partitioning defective 6 homolog beta. (393 aa)
	LOC106533834	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (598 aa)
	LOC106534497	DNA-binding protein Ikaros-like. (570 aa)
	LOC106534559	MAGUK p55 subfamily member 5-A-like; Belongs to the MAGUK family. (672 aa)
	crb3	Protein crumbs homolog 3. (127 aa)
	LOC106536983	Partitioning defective 3 homolog. (445 aa)
	LOC106537048	Protein crumbs homolog 2-like. (974 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511184	LOC106515202	A0A2I4AIS9	A0A2I4AXU4	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Multiple PDZ domain protein-like.	0.414
LOC106511184	LOC106515848	A0A2I4AIS9	A0A2I4B0R9	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Partitioning defective 6 homolog gamma-like.	0.413
LOC106511184	LOC106521063	A0A2I4AIS9	A0A2I4BMG6	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Partitioning defective 3 homolog.	0.404
LOC106511184	LOC106523998	A0A2I4AIS9	A0A2I4BZ94	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Partitioning defective 6 homolog alpha-like isoform X1.	0.413
LOC106511184	LOC106528062	A0A2I4AIS9	A0A2I4CF15	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	inaD-like protein.	0.414
LOC106511184	LOC106529583	A0A2I4AIS9	A0A2I4CKJ3	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Protein crumbs homolog 1-like isoform X1.	0.644
LOC106511184	LOC106532169	A0A2I4AIS9	A0A2I4CUH1	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	inaD-like protein.	0.414
LOC106511184	LOC106532170	A0A2I4AIS9	A0A2I4CUH4	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	inaD-like protein.	0.414
LOC106511184	LOC106536983	A0A2I4AIS9	A0A2I4DC36	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Partitioning defective 3 homolog.	0.404
LOC106511184	lnx1	A0A2I4AIS9	A0A2I4BZS5	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	E3 ubiquitin-protein ligase LNX isoform X1.	0.414
LOC106511184	mpdz	A0A2I4AIS9	A0A2I4AWA4	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Multiple PDZ domain protein.	0.414
LOC106511184	pard6b	A0A2I4AIS9	A0A2I4CUJ5	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	Partitioning defective 6 homolog beta.	0.413
LOC106511261	LOC106517273	A0A2I4AIY8	A0A2I4B6W6	Uncharacterized protein LOC106511261.	MAGUK p55 subfamily member 4-like; Belongs to the MAGUK family.	0.900
LOC106511261	LOC106521234	A0A2I4AIY8	A0A2I4BN38	Uncharacterized protein LOC106511261.	MAGUK p55 subfamily member 5-A-like; Belongs to the MAGUK family.	0.909
LOC106511261	LOC106534559	A0A2I4AIY8	A0A2I4D380	Uncharacterized protein LOC106511261.	MAGUK p55 subfamily member 5-A-like; Belongs to the MAGUK family.	0.909
LOC106511261	mpp4	A0A2I4AIY8	A0A2I4AMC1	Uncharacterized protein LOC106511261.	MAGUK p55 subfamily member 4 isoform X1; Belongs to the MAGUK family.	0.900
LOC106511261	mpp5	A0A2I4AIY8	A0A2I4BT96	Uncharacterized protein LOC106511261.	MAGUK p55 subfamily member 5; Belongs to the MAGUK family.	0.909
LOC106515202	LOC106511184	A0A2I4AXU4	A0A2I4AIS9	Multiple PDZ domain protein-like.	MAGUK p55 subfamily member 3-like; Belongs to the MAGUK family.	0.414
LOC106515202	LOC106515848	A0A2I4AXU4	A0A2I4B0R9	Multiple PDZ domain protein-like.	Partitioning defective 6 homolog gamma-like.	0.453
LOC106515202	LOC106521070	A0A2I4AXU4	A0A2I4BMF8	Multiple PDZ domain protein-like.	MAGUK p55 subfamily member 7-like.	0.414